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Medicine

D-Index
99
Citations
38769
World Ranking
8552
National Ranking
4403

Research.com Recognitions

  • 2019 - Fellow of the American Statistical Association (ASA)

Overview

John D. Shaughnessy is affiliated with the University of Arkansas for Medical Sciences in the United States. Their research focuses primarily on medicine with contributions to biochemistry, genetics, and molecular biology. They have substantial work in hematology, oncology, molecular biology, immunology, and pathology and forensic medicine.

The scientist's research has a strong emphasis on multiple myeloma, reflected in their extensive publication record. Key topics covered include:

  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis
  • Cancer Treatment and Pharmacology
  • CAR-T cell therapy research
  • Chemokine receptors and signaling
  • Ubiquitin and proteasome pathways

Prominent publication venues where John D. Shaughnessy has contributed include:

  • Blood
  • Blood Advances
  • Clinical Lymphoma Myeloma & Leukemia
  • Journal of Clinical Investigation
  • Cancers

Frequent co-authors collaborating with the scientist include:

  • Frits van Rhee
  • Maurizio Zangari
  • Carolina Schinke
  • Sharmilan Thanendrarajan
  • Samer Al Hadidi

Selected recent papers by John D. Shaughnessy demonstrate a focus on multiple myeloma biology, therapy, and disease progression:

  • Risks of infections associated with the use of bispecific antibodies in multiple myeloma: a pooled analysis, 2023, Blood Advances
  • TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies, 2021, Journal of Clinical Investigation
  • Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth, 2024, Nature Communications
  • Genetic analysis of multiple myeloma identifies cytogenetic alterations implicated in disease complexity and progression, 2021, Cancers
  • CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation, 2022, Journal of Clinical Investigation

John D. Shaughnessy has received recognition as a Fellow of the American Statistical Association (ASA) in 2019.

Best Publications

  • The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma

    Erming Tian;Fenghuang Zhan;Ronald Walker;Erik Rasmussen

  • The molecular classification of multiple myeloma

    Fenghuang Zhan;Yongsheng Huang;Yongsheng Huang;Simona Colla;Simona Colla;James P. Stewart;James P. Stewart

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

    R Fonseca;P L Bergsagel;J Drach;J Shaughnessy

  • Frequent Engagement of the Classical and Alternative NF-κB Pathways by Diverse Genetic Abnormalities in Multiple Myeloma

    Christina M. Annunziata;R. Eric Davis;Yulia Demchenko;William Bellamy

  • A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1

    John D. Shaughnessy;Fenghuang Zhan;Bart E. Burington;Yongsheng Huang

  • Genetics and Cytogenetics of Multiple Myeloma A Workshop Report

    Rafael Fonseca;Bart Barlogie;Regis Bataille;Christian Bastard

  • Absence epilepsy in tottering mutant mice is associated with calcium channel defects

    Colin F Fletcher;Cathleen M Lutz;T.Norene O'Sullivan;John D Shaughnessy

  • Thalidomide and hematopoietic-cell transplantation for multiple myeloma

    Bart Barlogie;Guido Tricot;Elias Anaissie;John Shaughnessy

  • Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

    P. Leif Bergsagel;W. Michael Kuehl;Fenghuang Zhan;Jeffrey Sawyer

  • Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

    Fenghuang Zhan;Johanna S. Hardin;Bob Kordsmeier;Klaus Bumm

  • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients.

    Bart Barlogie;Raman Desikan;Raman Desikan;Paul Eddlemon;Paul Eddlemon;Trey Spencer;Trey Spencer

  • Treatment of multiple myeloma

    Bart Barlogie;John D Shaughnessy;Guido Tricot;Joth Jacobson

  • CS1, a Potential New Therapeutic Antibody Target for the Treatment of Multiple Myeloma

    Eric D. Hsi;Roxanne Steinle;Balaji Balasa;Susann Szmania

  • Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

    Takuro Nakamura;David A. Largaespada;Maxwell P. Lee;Laura A. Johnson

  • Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation.

    Ichiro Hanamura;James P. Stewart;James P. Stewart;Yongsheng Huang;Yongsheng Huang;Fenghuang Zhan;Fenghuang Zhan

  • F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma

    Twyla B. Bartel;Jeff Haessler;Tracy L. Y. Brown;John D. Shaughnessy

  • High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.

    Daniel R. Carrasco;Giovanni Tonon;Yongsheng Huang;Yunyu Zhang

  • Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.

    Shmuel Yaccoby;Wen Ling;Fenghuang Zhan;Ronald Walker

  • The role of Dickkopf-1 in bone development, homeostasis, and disease

    Joseph J. Pinzone;Brett M. Hall;Nanda K. Thudi;Martin Vonau

Frequent Co-Authors

Bart Barlogie
Bart Barlogie Mount Sinai Hospital
Frits van Rhee
Frits van Rhee University of Arkansas for Medical Sciences
Joshua Epstein
Joshua Epstein University of Arkansas for Medical Sciences
John Crowley
John Crowley Washington University in St. Louis
Elias Anaissie
Elias Anaissie University of Cincinnati
Guido Tricot
Guido Tricot University of Iowa
Maurizio Zangari
Maurizio Zangari University of Arkansas for Medical Sciences
Saad Z. Usmani
Saad Z. Usmani Memorial Sloan Kettering Cancer Center
Thierry Rème
Thierry Rème Grenoble Alpes University
Madhav V. Dhodapkar
Madhav V. Dhodapkar Emory University

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