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Rafael Fonseca

Rafael Fonseca

D-Index & Metrics

Medicine

D-Index
131
Citations
62246
World Ranking
2403
National Ranking
1359

Overview

Rafael Fonseca is affiliated with the Mayo Clinic in the United States and has an extensive publication record primarily in medicine, with contributions to biochemistry, genetics, and molecular biology. The scientist's work is particularly concentrated in hematology, molecular biology, oncology, genetics, and immunology.

Fonseca's research spans several core topics, including:

  • Multiple Myeloma Research and Treatments
  • Protein Degradation and Inhibitors
  • Peptidase Inhibition and Analysis
  • CAR-T Cell Therapy Research
  • Chronic Lymphocytic Leukemia Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cancer Treatment and Pharmacology

Several of Fonseca's recent papers reflect ongoing work in multiple myeloma and related hematological conditions:

  • "Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma," 2020, Nature Cancer
  • "Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group," 2021, The Lancet Oncology
  • "Cevostamab Monotherapy Continues to Show Clinically Meaningful Activity and Manageable Safety in Patients with Heavily Pre-Treated Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from an Ongoing Phase I Study," 2021, Blood
  • "Targeting TMPRSS2 in SARS-CoV-2 Infection," 2020, Mayo Clinic Proceedings
  • "Chromosome 1q21 abnormalities in multiple myeloma," 2021, Blood Cancer Journal

Fonseca frequently publishes in the following venues:

  • Blood (59 publications)
  • Clinical Lymphoma Myeloma & Leukemia (30 publications)
  • Blood Cancer Journal (23 publications)
  • Journal of Clinical Oncology (11 publications)
  • Mayo Clinic Proceedings (7 publications)

Key collaborators in Fonseca's research include Shaji Kumar, P. Leif Bergsagel, Prashant Kapoor, Taxiarchis Kourelis, and Sikander Ailawadhi, each with multiple joint publications.

In addition to journal articles, Rafael Fonseca has contributed to book publications, including a title published by Dialética eBooks in 2023 focusing on the prevalence of overweight/obesity and associated factors in basic education teachers.

Best Publications

  • Review of 1027 Patients With Newly Diagnosed Multiple Myeloma

    Robert A. Kyle;Morie A. Gertz;Thomas E. Witzig;John A. Lust

  • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group

    Robert A. Kyle;J. Anthony Child;Kenneth Anderson;Bart Barlogie

  • Initial genome sequencing and analysis of multiple myeloma

    Michael A. Chapman;Michael S. Lawrence;Jonathan J. Keats;Kristian Cibulskis

  • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial

    S Vincent Rajkumar;Susanna Jacobus;Natalie S Callander;Rafael Fonseca

  • Phase III Clinical Trial of Thalidomide Plus Dexamethasone Compared With Dexamethasone Alone in Newly Diagnosed Multiple Myeloma: A Clinical Trial Coordinated by the Eastern Cooperative Oncology Group

    S. Vincent Rajkumar;Emily Blood;David Vesole;Rafael Fonseca

  • Promiscuous Mutations Activate the Noncanonical NF-κB Pathway in Multiple Myeloma

    Jonathan J. Keats;Rafael Fonseca;Marta Chesi;Roelandt Schop

  • International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

    R Fonseca;P L Bergsagel;J Drach;J Shaughnessy

  • Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma.

    Robert A. Kyle;Ellen D. Remstein;Terry M. Therneau;Angela Dispenzieri

  • Clinicopathological definition of Waldenstrom's macroglobulinemia: Consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia

    Roger G. Owen;Steven P. Treon;Ayad Al-Katib;Rafael Fonseca

  • Serum Cardiac Troponins and N-Terminal Pro-Brain Natriuretic Peptide: A Staging System for Primary Systemic Amyloidosis

    Angela Dispenzieri;Morie A. Gertz;Robert A. Kyle;Martha Q. Lacy

  • POEMS syndrome: definitions and long-term outcome.

    Angela Dispenzieri;Robert A. Kyle;Martha Q. Lacy;S. Vincent Rajkumar

  • Genetics and Cytogenetics of Multiple Myeloma A Workshop Report

    Rafael Fonseca;Bart Barlogie;Regis Bataille;Christian Bastard

  • Clinical and biologic implications of recurrent genomic aberrations in myeloma

    Rafael Fonseca;Emily Blood;Montserrat Rue;David Harrington

  • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma.

    S. Vincent Rajkumar;Suzanne R. Hayman;Martha Q. Lacy;Angela Dispenzieri

  • Clonal competition with alternating dominance in multiple myeloma

    Jonathan J. Keats;Marta Chesi;Jan B. Egan;Victoria M. Garbitt

  • Combination Therapy With Thalidomide Plus Dexamethasone for Newly Diagnosed Myeloma

    S. Vincent Rajkumar;Suzanne Hayman;Morie A. Gertz;Angela Dispenzieri

  • IMWG consensus on risk stratification in multiple myeloma

    W J Chng;A Dispenzieri;C-S Chim;R Fonseca

  • Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

    Yuan Xiao Zhu;Esteban Braggio;Chang Xin Shi;Laura A. Bruins

  • Management of Newly Diagnosed Symptomatic Multiple Myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines

    Shaji K. Kumar;Joseph R. Mikhael;Francis K. Buadi;David Dingli

  • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Commentary

    Michele Cavo;S. Vincent Rajkumar;Suzanne R. Hayman;Martha Q. Lacy

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