D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 80 Citations 23,574 204 World Ranking 1738 National Ranking 28

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

Hakon Leffler focuses on Biochemistry, Galectin, Lectin, Galectin-3 and Cell biology. He does research in Galectin, focusing on Galectin-8 specifically. His Lectin research integrates issues from Protein subunit, Stereochemistry, Recombinant DNA and Glycoprotein.

His Galectin-3 research is multidisciplinary, incorporating elements of Fibrosis, Pulmonary fibrosis, Transforming growth factor and Idiopathic pulmonary fibrosis. His research in Cell biology intersects with topics in Apical membrane, Secretion and Regulation of gene expression. His Galectin-1 research is multidisciplinary, relying on both Substrate specificity, Computational biology and Animal Lectins.

His most cited work include:

  • Galectins. Structure and function of a large family of animal lectins. (1282 citations)
  • Galectins: a family of animal beta-galactoside-binding lectins. (986 citations)
  • Introduction to galectins (560 citations)

What are the main themes of his work throughout his whole career to date?

Hakon Leffler mainly investigates Biochemistry, Galectin, Galectin-3, Stereochemistry and Glycolipid. His work on Biochemistry deals in particular with Lectin, Glycoprotein, Binding site, Glycan and Receptor. His Galectin research incorporates themes from Glycoconjugate, Galectin-1 and Galactose.

His research integrates issues of Cancer research and Idiopathic pulmonary fibrosis in his study of Galectin-3. His study in Stereochemistry is interdisciplinary in nature, drawing from both Residue, Triazole, Chemical synthesis and Carbohydrate. His research investigates the link between Glycolipid and topics such as Microbiology that cross with problems in Bacteria, Agglutination, Urinary system, Bacterial adhesin and Epithelium.

He most often published in these fields:

  • Biochemistry (40.56%)
  • Galectin (34.27%)
  • Galectin-3 (17.83%)

What were the highlights of his more recent work (between 2011-2021)?

  • Galectin (34.27%)
  • Galectin-3 (17.83%)
  • Biochemistry (40.56%)

In recent papers he was focusing on the following fields of study:

Galectin, Galectin-3, Biochemistry, Stereochemistry and Cell biology are his primary areas of study. He has included themes like Lectin, Galactose, Carbohydrate, Glycoprotein and Binding site in his Galectin study. His research investigates the connection between Binding site and topics such as Glycoconjugate that intersect with problems in ADME.

His biological study spans a wide range of topics, including Fibrosis, Galectin-1 and Idiopathic pulmonary fibrosis. Hakon Leffler interconnects Triazole and Ligand in the investigation of issues within Stereochemistry. His Cell biology research incorporates elements of Immunology, Receptor, Cell and Microglia.

Between 2011 and 2021, his most popular works were:

  • Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3 (259 citations)
  • Galectins at a glance. (162 citations)
  • Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation (154 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

Hakon Leffler mostly deals with Galectin-3, Galectin, Biochemistry, Cell biology and Binding site. Hakon Leffler combines subjects such as Cancer research, Extracellular, PD-L1 and Fibrosis, Pulmonary fibrosis with his study of Galectin-3. His studies deal with areas such as Angiogenesis, Galactose and Protein secondary structure as well as Galectin.

His Galactose study combines topics from a wide range of disciplines, such as Galectin-1, Fluorine and Stereochemistry. His research combines Cholera toxin and Biochemistry. His Cell biology research incorporates themes from Immunology, In vitro, Macrophage and Microglia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Galectins. Structure and function of a large family of animal lectins.

S. H. Barondes;D. N. W. Cooper;M. A. Gitt;H. Leffler.
Journal of Biological Chemistry (1994)

2032 Citations

Galectins: a family of animal beta-galactoside-binding lectins.

Samuel H. Barondes;Vincent Castronovo;Douglas N W Cooper;Richard D. Cummings.
Cell (1994)

1449 Citations

Introduction to galectins

Hakon Leffler;Susanne Carlsson;Maria Hedlund;Yuning Qian.
Glycoconjugate Journal (2002)

859 Citations

Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary tract epithelial cells and agglutinating human erythrocytes

H. Leffler;Catharina Svanborg Edén.
Fems Microbiology Letters (1980)

631 Citations

Regulation of Alternative Macrophage Activation by Galectin-3

Alison C. MacKinnon;Sarah L. Farnworth;Philip S. Hodkinson;Neil C. Henderson.
Journal of Immunology (2008)

551 Citations

Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

Sean R. Stowell;Connie M. Arthur;Padmaja Mehta;Kristen A. Slanina.
Journal of Biological Chemistry (2008)

462 Citations

X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution.

J. Seetharaman;Amit Kanigsberg;Rita Slaaby;Hakon Leffler.
Journal of Biological Chemistry (1998)

457 Citations

Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin

Stefan Hemmerich;Hakon Leffler;Steven D. Rosen.
Journal of Biological Chemistry (1995)

400 Citations

Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides.

Hakon Leffler;Samuel H. Barondes.
Journal of Biological Chemistry (1986)

387 Citations

X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution.

Y D Lobsanov;M A Gitt;H Leffler;S H Barondes.
Journal of Biological Chemistry (1993)

372 Citations

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