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Hakon Leffler

Hakon Leffler

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Biology and Biochemistry 99 1604 1448 27 23 330 32069

Hakon Leffler publications per year

The chart shows the history of publications by Hakon Leffler between 1972 and 2026, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hakon Leffler published across 55 years, from 1972 to 2026, averaging 7 papers a year. Output peaked at 28 publications in 2023. 10 of the 384 publications appeared in the last two years.

No. of publications
5 10 15 20 25
Bar chart. Horizontal axis: year, 1972 to 2026. Vertical axis: number of publications, 0 to 28. Peak 28 publications in 2023. 1972: 1 publication 1973: 0 publications 1974: 1 publication 1975: 0 publications 1976: 0 publications 1977: 0 publications 1978: 1 publication 1979: 3 publications 1980: 6 publications 1981: 9 publications 1982: 11 publications 1983: 9 publications 1984: 8 publications 1985: 3 publications 1986: 3 publications 1987: 8 publications 1988: 2 publications 1989: 6 publications 1990: 4 publications 1991: 4 publications 1992: 3 publications 1993: 9 publications 1994: 5 publications 1995: 6 publications 1996: 3 publications 1997: 5 publications 1998: 6 publications 1999: 4 publications 2000: 1 publication 2001: 7 publications 2002: 14 publications 2003: 9 publications 2004: 4 publications 2005: 7 publications 2006: 6 publications 2007: 8 publications 2008: 12 publications 2009: 5 publications 2010: 14 publications 2011: 12 publications 2012: 13 publications 2013: 10 publications 2014: 11 publications 2015: 5 publications 2016: 14 publications 2017: 2 publications 2018: 14 publications 2019: 14 publications 2020: 7 publications 2021: 11 publications 2022: 11 publications 2023: 28 publications 2024: 15 publications 2025: 8 publications 2026: 2 publications
1972 2026

384 publications in total across all disciplines

View publications per year as a table
Hakon Leffler: publications per year, 1972 to 2026
Year Publications
1972 1
1973 0
1974 1
1975 0
1976 0
1977 0
1978 1
1979 3
1980 6
1981 9
1982 11
1983 9
1984 8
1985 3
1986 3
1987 8
1988 2
1989 6
1990 4
1991 4
1992 3
1993 9
1994 5
1995 6
1996 3
1997 5
1998 6
1999 4
2000 1
2001 7
2002 14
2003 9
2004 4
2005 7
2006 6
2007 8
2008 12
2009 5
2010 14
2011 12
2012 13
2013 10
2014 11
2015 5
2016 14
2017 2
2018 14
2019 14
2020 7
2021 11
2022 11
2023 28
2024 15
2025 8
2026 2
Total 384
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Hakon Leffler publications per year - data summary

  • Hakon Leffler, a Biology and Biochemistry scholar from Lund University, has 384 publications recorded across 55 years, from 1972 to 2026.
  • The oldest publication on record dates to 1972 and the most recent to 2026.
  • The most productive year is 2023, with 28 publications.
  • The least productive years with any output are 1972, 1974, 1978 and 2000, with 1 publication each.
  • 4 of the 55 years in the span carry no publications at all (1973, 1975, 1976 and 1977).
  • The rate of publication averages 7.0 papers per year over the whole span, or 7.5 per year counting only the 51 years with at least one publication.
  • The last 5 years on the chart (2022-2026) hold 64 publications, 17% of the career total.
  • Split into equal eras - 1972-1990: 75 publications (3.9 per year); 1991-2009: 118 publications (6.2 per year); 2010-2026: 191 publications (11.2 per year).
  • Comparing the opening and closing eras, the overall trend of publication is rising.

Hakon Leffler publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hakon Leffler sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 327–336 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 330 publications — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315
317–326 296
327–336 261 330
337–346 240
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
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Hakon Leffler publication distribution in Biology and Biochemistry in 2026 - data summary

  • The chart plots the publication count of all 19,587 Biology and Biochemistry scientists ranked by Research.com in 2026, grouped into 100 ranges running from 47–56 to 1,028+ publications.
  • Hakon Leffler, a Biology and Biochemistry scholar from Lund University, records 330 publications - the 83rd percentile of the discipline.
  • 83% of ranked Biology and Biochemistry scientists score the same or lower than Hakon Leffler, and about 17% score higher.
  • The median of the discipline falls in the 197–206 publications range, and Hakon Leffler ranks above the median.
  • The most crowded range is 127–136 publications, holding 980 scientists (5% of the field).
  • 77% of the field sits in the lowest quarter of the value range (up to 287–296 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 1,028 publications or more, 100 scientists in all (<1% of the field).

Hakon Leffler D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hakon Leffler sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 98–99 D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 99 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714
72–73 709
74–75 596
76–77 512
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157 99
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98
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Hakon Leffler D-index placement in Biology and Biochemistry in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 19,587 Biology and Biochemistry scientists ranked by Research.com in 2026, grouped into 65 ranges running from 40–41 to 167+ D-Index.
  • Hakon Leffler, a Biology and Biochemistry scholar from Lund University, records 99 D-Index - the 92nd percentile of the discipline.
  • 92% of ranked Biology and Biochemistry scientists score the same or lower than Hakon Leffler, and about 8% score higher.
  • The median of the discipline falls in the 64–65 D-Index range, and Hakon Leffler ranks above the median.
  • The most crowded range is 58–59 D-Index, holding 1,253 scientists (6% of the field).
  • 71% of the field sits in the lowest quarter of the value range (up to 72–73 D-Index), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 167 D-Index or more, 98 scientists in all (<1% of the field).

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Hakon Leffler is affiliated with Lund University in Sweden, specializing in research primarily within immunology and microbiology as well as biochemistry, genetics, and molecular biology. Their work extensively covers molecular mechanisms related to galectins, glycosylation, and signaling pathways in disease, with a focus on the biological and pathological roles of galectin-3.

Leffler's recent research publications include the following:

  • Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis, 2020, European Respiratory Journal
  • Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease, 2022, Journal of Medicinal Chemistry
  • Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C, 2021, JACS Au
  • Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression, 2021, Gastric Cancer
  • Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants, 2023, Cancer Chemotherapy and Pharmacology

Their frequent co-authors include:

  • Ulf J. Nilsson
  • Fredrik R. Zetterberg
  • Robert J. Slack
  • Barbro Kahl-Knutson
  • Kristoffer Peterson

Common publication venues for this scientist comprise:

  • Journal of Medicinal Chemistry
  • ChemMedChem
  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience
  • Frontiers in Pharmacology

The primary fields of study are:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these fields, the notable subfields of study include:

  • Immunology
  • Molecular Biology
  • Oncology
  • Cell Biology
  • Pulmonary and Respiratory Medicine

The main research topics addressed by Leffler involve:

  • Galectins and Cancer Biology
  • Glycosylation and Glycoproteins Research
  • Signaling Pathways in Disease
  • Toxin Mechanisms and Immunotoxins
  • Peptidase Inhibition and Analysis
  • Macrophage Migration Inhibitory Factor
  • Protein Tyrosine Phosphatases

Best Publications

  • Galectins. Structure and function of a large family of animal lectins.

    S. H Barondes;D. N. W Cooper;M. A Gitt;H Leffler

  • Galectins: a family of animal beta-galactoside-binding lectins.

    Samuel H. Barondes;Vincent Castronovo;Douglas N W Cooper;Richard D. Cummings

  • Introduction to galectins

    Hakon Leffler;Susanne Carlsson;Maria Hedlund;Yuning Qian

  • Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary tract epithelial cells and agglutinating human erythrocytes

    H. Leffler;Catharina Svanborg Edén

  • Regulation of Alternative Macrophage Activation by Galectin-3

    Alison C. MacKinnon;Sarah L. Farnworth;Philip S. Hodkinson;Neil C. Henderson

  • Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-3

    Alison C. Mackinnon;Michael A. Gibbons;Sarah L. Farnworth;Hakon Leffler

  • Galectins at a glance.

    Ludger Johannes;Ralf Jacob;Hakon Leffler

  • Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

    Sean R. Stowell;Connie M. Arthur;Padmaja Mehta;Kristen A. Slanina

  • X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution.

    J. Seetharaman;Amit Kanigsberg;Rita Slaaby;Hakon Leffler

  • Galectin-3, a marker for vacuole lysis by invasive pathogens.

    Irit Paz;Martin Sachse;Nicolas Dupont;Joelle Mounier

  • Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin

    Stefan Hemmerich;Hakon Leffler;Steven D. Rosen

  • Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides.

    Hakon Leffler;Samuel H. Barondes

  • Multiple soluble beta-galactoside-binding lectins from human lung.

    C P Sparrow;H Leffler;S H Barondes

  • X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution.

    Y D Lobsanov;M A Gitt;H Leffler;S H Barondes

  • Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids.

    K Bock;M E Breimer;A Brignole;G C Hansson

  • Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells

    B Andersson;J Dahmén;T Frejd;H Leffler

  • Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation

    Miguel Angel Burguillos;Miguel Angel Burguillos;Martina Svensson;Tim Schulte;Antonio Boza-Serrano

  • Phylogenetic Analysis of the Vertebrate Galectin Family

    Denis Houzelstein;Isabelle R. Gonçalves;Andrew J. Fadden;Sukhvinder S. Sidhu

  • L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity

    Stephen M. Massa;Douglas N. W. Cooper;Hakon Leffler;Samuel H. Barondes

  • Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils.

    Anna Karlsson;Per Follin;Hakon Leffler;Claes Dahlgren

Frequent Co-Authors

Ulf J. Nilsson
Ulf J. Nilsson Lund University
Gunnar C. Hansson
Gunnar C. Hansson University of Gothenburg
Karl-Anders Karlsson
Karl-Anders Karlsson University of Gothenburg
Samuel H. Barondes
Samuel H. Barondes University of California, San Francisco
Anna Karlsson
Anna Karlsson Skåne University Hospital
Susan J. Fisher
Susan J. Fisher University of California, San Francisco
Ulf Ryde
Ulf Ryde Lund University
Mikael Akke
Mikael Akke Lund University
Göran Larson
Göran Larson University of Gothenburg
Ulf Jodal
Ulf Jodal University of Gothenburg

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