Hakon Leffler focuses on Biochemistry, Galectin, Lectin, Galectin-3 and Cell biology. He does research in Galectin, focusing on Galectin-8 specifically. His Lectin research integrates issues from Protein subunit, Stereochemistry, Recombinant DNA and Glycoprotein.
His Galectin-3 research is multidisciplinary, incorporating elements of Fibrosis, Pulmonary fibrosis, Transforming growth factor and Idiopathic pulmonary fibrosis. His research in Cell biology intersects with topics in Apical membrane, Secretion and Regulation of gene expression. His Galectin-1 research is multidisciplinary, relying on both Substrate specificity, Computational biology and Animal Lectins.
Hakon Leffler mainly investigates Biochemistry, Galectin, Galectin-3, Stereochemistry and Glycolipid. His work on Biochemistry deals in particular with Lectin, Glycoprotein, Binding site, Glycan and Receptor. His Galectin research incorporates themes from Glycoconjugate, Galectin-1 and Galactose.
His research integrates issues of Cancer research and Idiopathic pulmonary fibrosis in his study of Galectin-3. His study in Stereochemistry is interdisciplinary in nature, drawing from both Residue, Triazole, Chemical synthesis and Carbohydrate. His research investigates the link between Glycolipid and topics such as Microbiology that cross with problems in Bacteria, Agglutination, Urinary system, Bacterial adhesin and Epithelium.
Galectin, Galectin-3, Biochemistry, Stereochemistry and Cell biology are his primary areas of study. He has included themes like Lectin, Galactose, Carbohydrate, Glycoprotein and Binding site in his Galectin study. His research investigates the connection between Binding site and topics such as Glycoconjugate that intersect with problems in ADME.
His biological study spans a wide range of topics, including Fibrosis, Galectin-1 and Idiopathic pulmonary fibrosis. Hakon Leffler interconnects Triazole and Ligand in the investigation of issues within Stereochemistry. His Cell biology research incorporates elements of Immunology, Receptor, Cell and Microglia.
Hakon Leffler mostly deals with Galectin-3, Galectin, Biochemistry, Cell biology and Binding site. Hakon Leffler combines subjects such as Cancer research, Extracellular, PD-L1 and Fibrosis, Pulmonary fibrosis with his study of Galectin-3. His studies deal with areas such as Angiogenesis, Galactose and Protein secondary structure as well as Galectin.
His Galactose study combines topics from a wide range of disciplines, such as Galectin-1, Fluorine and Stereochemistry. His research combines Cholera toxin and Biochemistry. His Cell biology research incorporates themes from Immunology, In vitro, Macrophage and Microglia.
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Galectins. Structure and function of a large family of animal lectins.
S. H. Barondes;D. N. W. Cooper;M. A. Gitt;H. Leffler.
Journal of Biological Chemistry (1994)
Galectins: a family of animal beta-galactoside-binding lectins.
Samuel H. Barondes;Vincent Castronovo;Douglas N W Cooper;Richard D. Cummings.
Cell (1994)
Introduction to galectins
Hakon Leffler;Susanne Carlsson;Maria Hedlund;Yuning Qian.
Glycoconjugate Journal (2002)
Chemical identification of a glycosphingolipid receptor for Escherichia coli attaching to human urinary tract epithelial cells and agglutinating human erythrocytes
H. Leffler;Catharina Svanborg Edén.
Fems Microbiology Letters (1980)
Regulation of Alternative Macrophage Activation by Galectin-3
Alison C. MacKinnon;Sarah L. Farnworth;Philip S. Hodkinson;Neil C. Henderson.
Journal of Immunology (2008)
Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens
Sean R. Stowell;Connie M. Arthur;Padmaja Mehta;Kristen A. Slanina.
Journal of Biological Chemistry (2008)
X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution.
J. Seetharaman;Amit Kanigsberg;Rita Slaaby;Hakon Leffler.
Journal of Biological Chemistry (1998)
Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin
Stefan Hemmerich;Hakon Leffler;Steven D. Rosen.
Journal of Biological Chemistry (1995)
Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides.
Hakon Leffler;Samuel H. Barondes.
Journal of Biological Chemistry (1986)
X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution.
Y D Lobsanov;M A Gitt;H Leffler;S H Barondes.
Journal of Biological Chemistry (1993)
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