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Biology and Biochemistry

D-Index
71
Citations
14997
World Ranking
6778
National Ranking
487

Overview

Herbert Kaltner is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on Immunology and Microbiology, as well as Biochemistry, Genetics and Molecular Biology. Within these fields, Kaltner's work extends across subfields including Immunology, Molecular Biology, Organic Chemistry, Radiology, Nuclear Medicine and Imaging, and Oncology.

The main research topics covered by Kaltner include:

  • Galectins and Cancer Biology
  • Glycosylation and Glycoproteins Research
  • Signaling Pathways in Disease
  • Toxin Mechanisms and Immunotoxins
  • Carbohydrate Chemistry and Synthesis
  • Monoclonal and Polyclonal Antibodies Research
  • Peptidase Inhibition and Analysis

Kaltner has contributed to numerous peer-reviewed publications. Notable recent papers include:

  • "Chemokines and galectins form heterodimers to modulate inflammation," 2020, EMBO Reports
  • "What is the Sugar Code?", 2021, ChemBioChem
  • "Influence of protein (human galectin-3) design on aspects of lectin activity," 2020, Histochemistry and Cell Biology
  • "Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes," 2020, iScience
  • "Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin," 2021, Biochemistry

Frequent coauthors collaborating with Kaltner include:

  • Hans-Joachim Gabius
  • Anna-Kristin Ludwig
  • Joachim C. Manning
  • Mare Čudić
  • Gabriel García Caballero

Kaltner publishes regularly in a set of key scientific venues, such as:

  • ChemBioChem
  • Histochemistry and Cell Biology
  • Methods in Molecular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomolecules

Best Publications

  • Galectin-3 Precipitates as a Pentamer with Synthetic Multivalent Carbohydrates and Forms Heterogeneous Cross-linked Complexes

    Nisar Ahmad;Hans J. Gabius;Sabine André;Herbert Kaltner

  • The sugar code: functional lectinomics.

    Hans-Joachim Gabius;Sabine André;Herbert Kaltner;Hans-Christian Siebert

  • Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

    Jürgen Kopitz;Carolina von Reitzenstein;Sabine André;Herbert Kaltner

  • Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants.

    Tarun K. Dam;Hans J. Gabius;Sabine André;Herbert Kaltner

  • Growth-Regulatory Human Galectin-1: Crystallographic Characterisation of the Structural Changes Induced by Single-Site Mutations and Their Impact on the Thermodynamics of Ligand Binding

    María F. López-Lucendo;Dolores Solís;Sabine André;Jun Hirabayashi

  • Human Galectin-2: Novel Inducer of T Cell Apoptosis with Distinct Profile of Caspase Activation

    Andreas Sturm;Martin Lensch;Sabine André;Herbert Kaltner

  • ANIMAL LECTINS AS CELL ADHESION MOLECULES

    H. Kaltner;B. Stierstorfer

  • Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures

    Harald Lahm;Sabine Andre;Andreas Hoeflich;Jiirgen R. Fischer

  • Wedgelike Glycodendrimers as Inhibitors of Binding of Mammalian Galectins to Glycoproteins, Lactose Maxiclusters, and Cell Surface Glycoconjugates

    Sabine André;Roland J. Pieters;Ioannis Vrasidas;Herbert Kaltner

  • Galectins-1 and -3 and their ligands in tumor biology. Non-uniform properties in cell-surface presentation and modulation of adhesion to matrix glycoproteins for various tumor cell lines, in biodistribution of free and liposome-bound galectins and in their expression by breast and colorectal carcinomas with/without metastatic propensity.

    Sabine André;Shuji Kojima;Noboru Yamazaki;Christian Fink

  • Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases.

    Isabelle Camby;Nathalie Belot;Florence Lefranc;Niloufar Sadeghi

  • Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration.

    Isabelle Camby;Nathalie Belot;Sandrine Rorive;Florence Lefranc

  • Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets.

    Sabine André;Herbert Kaltner;Tetsuya Furuike;Shin-Ichiro Nishimura

  • Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases

    Klaus Kayser;Stefan Zink;Thomas Schneider;Hendrik Dienemann

  • Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting

    Nathalie Nagy;Hugues Legendre;Olivier Engels;Sabine André

  • Tumor galectinology: insights into the complex network of a family of endogenous lectins.

    Harald Lahm;Sabine André;Andreas Hoeflich;Herbert Kaltner

  • Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a Glycoprotein and Cell‐Surface Glycoconjugates and Selectivity among Human Adhesion/Growth‐Regulatory Galectins

    Sabine André;Francesco Sansone;Herbert Kaltner;Alessandro Casnati

  • Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma.

    Sandrine Rorive;Nathalie Belot;Christine Decaestecker;Florence Lefranc

  • Galectin-1(L11A) Predicted from a Computed Galectin-1 Farnesyl-Binding Pocket Selectively Inhibits Ras-GTP

    Barak Rotblat;Hagit Niv;Sabine André;Herbert Kaltner

  • A toolbox of lectins for translating the sugar code: the galectin network in phylogenesis and tumors.

    Herbert Kaltner;Hans-Joachim Gabius

Frequent Co-Authors

Hans-Joachim Gabius
Hans-Joachim Gabius Ludwig-Maximilians-Universität München
Sabine André
Sabine André Ludwig-Maximilians-Universität München
Jürgen Kopitz
Jürgen Kopitz Heidelberg University
Nicolai V. Bovin
Nicolai V. Bovin Russian Academy of Sciences
Robert Kiss
Robert Kiss Université Libre de Bruxelles
Karel Smetana
Karel Smetana Charles University
Fred Sinowatz
Fred Sinowatz Ludwig-Maximilians-Universität München
Isabelle Salmon
Isabelle Salmon Université Libre de Bruxelles
Antonio A. Romero
Antonio A. Romero Spanish National Research Council
Yehiel Zick
Yehiel Zick Weizmann Institute of Science

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