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Karel Smetana

Karel Smetana

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9800
World Ranking
16684
National Ranking
20

Overview

Karel Smetana is affiliated with Charles University in the Czech Republic and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The scientist's work spans major subfields such as Molecular Biology, Oncology, Immunology, Rehabilitation, and Cancer Research.

The primary topics explored in this researcher's publications include:

  • Wound Healing and Treatments
  • Cancer Cells and Metastasis
  • Cytokine Signaling Pathways and Interactions
  • COVID-19 Clinical Research Studies
  • Immunotherapy and Immune Responses
  • Dermatologic Treatments and Research
  • Cancer Immunotherapy and Biomarkers

Smetana has published several papers of note, among them:

  • The Role of IL-6 in Cancer Cell Invasiveness and Metastasis-Overview and Therapeutic Opportunities (2022, Cells)
  • Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at All Wound Healing Stages (Inflammation, Proliferation and Maturation) (2021, International Journal of Molecular Sciences)
  • Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19 (2020, International Journal of Molecular Sciences)
  • IL-6 in the Ecosystem of Head and Neck Cancer: Possible Therapeutic Perspectives (2021, International Journal of Molecular Sciences)
  • Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality (2020, In Vivo)

The researcher's frequent co-authors include Lukáš Lacina, Michal Kolář, Barbora Dvořánková, Péter Gál, and Pavol Szabó, with collaboration counts ranging from 11 to 29 shared publications.

Publications by Smetana often appear in key journals such as:

  • International Journal of Molecular Sciences
  • Histochemistry and Cell Biology
  • Folia Biologica
  • Physiological Research
  • In Vivo

Best Publications

  • The Miniature Pig as an Animal Model in Biomedical Research

    Petr Vodička;Karel Smetana;Barbora Dvořánková;Teresa Emerick

  • Cell biology of hydrogels

    Karel Smetana

  • Proteins C23 and B23 are the major nucleolar silver staining proteins

    Michael A. Lischwe;Karel Smetana;Mark O.J. Olson;Harris Busch

  • Quantitative Aspects of Isolation of Nucleoli of the Walker Carcinosarcoma and Liver of the Rat

    Masami Muramatsu;Karel Smetana;Harris Busch

  • Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

    Ondřej Kodet;Lukáš Lacina;Lukáš Lacina;Eliška Krejčí;Barbora Dvořánková

  • The nucleolus of the cancer cell: a review.

    Harris Busch;Paul Byvoet;Karel Smetana

  • A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code

    Dolores Solís;Nicolai V. Bovin;Anthony P. Davis;Jesús Jiménez-Barbero

  • The influence of hydrogel functional groups on cell behavior.

    K. Smetana;J. Vacík;D. Součková;Z. Krčová

  • Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells.

    Dana Grebenová;Katerina Kuzelová;Karel Smetana;Michaela Pluskalová

  • Ageing as an Important Risk Factor for Cancer

    Karel Smetana;Lukáš Lacina;Pavol Szabo;Barbora Dvořánková

  • New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

    Tereza Purkrábková;Karel Smetana;Barbora Dvořánková;Zuzana Holíková

  • Evidence from studies on segregated nucleoli that nucleolar silver staining proteins C23 and B23 are in the fibrillar component

    Y. Daskal;K. Smetana;H. Busch

  • A nucleolar antigen found in a broad range of human malignant tumor specimens.

    Harris Busch;Ferenc Gyorkey;Rose K. Busch;Frances M. Davis

  • Silver staining of nucleolar granules in tumor cells.

    Harris Busch;Yerach Daskal;Ferenc Gyorkey;Karel Smetana

  • Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness.

    Njainday Pulo Jobe;Daniel Rösel;Barbora Dvořánková;Ondřej Kodet

  • Proliferating cell nuclear antigen (PCNA) and human malignant tumor nucleolar antigens (HMTNA) in nucleoli of human hematological malignancies.

    Karel Smetana;Ferenc Gyorkey;Pui-Kwong Chan;Eng Tan

  • Galectin-3 - an emerging prognostic indicator in advanced head and neck carcinoma.

    Jan Plzák;Jan Betka;Karel Smetana;Martin Chovanec

  • Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

    Karel Smetana;Sabine André;Herbert Kaltner;Jürgen Kopitz

  • Soft intracameral lens

    Jiri Sulc;Zuzana Krcova;Karel Smetana;Sarka Pitrova

  • Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses.

    Michal Kolář;Pavol Szabo;Pavol Szabo;Barbora Dvořánková;Barbora Dvořánková;Lukáš Lacina;Lukáš Lacina

Frequent Co-Authors

Hans-Joachim Gabius
Hans-Joachim Gabius Ludwig-Maximilians-Universität München
Harris Busch
Harris Busch Baylor College of Medicine
Sabine André
Sabine André Ludwig-Maximilians-Universität München
Herbert Kaltner
Herbert Kaltner Ludwig-Maximilians-Universität München
Fu-Tong Liu
Fu-Tong Liu Academia Sinica
Jan Trka
Jan Trka Charles University
Nicolai V. Bovin
Nicolai V. Bovin Russian Academy of Sciences
Marc Thiry
Marc Thiry University of Liège
Sem Saeland
Sem Saeland Schering-Plough
Anna Sediva
Anna Sediva University Hospital in Motol

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