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Immunology

D-Index
44
Citations
8611
World Ranking
4766
National Ranking
5

Overview

Anna Sediva is affiliated with the University Hospital in Motol in the Czech Republic. Their research spans multiple fields in medicine, with a particular focus on immunology and microbiology. They have contributed extensively to the understanding of immune system disorders and infectious diseases.

The primary areas of study for Sediva include immunology, infectious diseases, genetics, molecular biology, and surgery. Their work covers a variety of key topics such as immunodeficiency and autoimmune disorders, COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, immune cell function and interaction, chronic lymphocytic leukemia research, T-cell and B-cell immunology, and blood disorders and treatments.

Anna Sediva has published in several scientific journals, often focusing on clinical and immunological research. Frequent publication venues include:

  • Journal of Clinical Immunology
  • Frontiers in Immunology
  • Journal of Allergy and Clinical Immunology
  • Clinical Immunology
  • Pediatric Allergy and Immunology

Among recent notable papers, the following are included:

  • Human genetic and immunological determinants of critical COVID-19 pneumonia, 2022, Nature
  • Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI), 2020, Allergy
  • Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations, 2021, Journal of Allergy and Clinical Immunology
  • SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?, 2021, The Journal of Experimental Medicine
  • Studying severe long COVID to understand post-infectious disorders beyond COVID-19, 2022, Nature Medicine

Collaboration is a significant aspect of Sediva's work. Frequent co-authors include:

  • Adam Klocperk
  • Markéta Bloomfield
  • Zuzana Paračková
  • Tomáš Milota
  • Filomeen Haerynck

With over 126 publications in medicine and 87 specifically in immunology and microbiology, Sediva's research is situated at the intersection of experimental and clinical investigation. Their contributions address both fundamental immunology and applied clinical research, particularly in immunodeficiency and infectious disease contexts.

Best Publications

  • Clinical picture and treatment of 2212 patients with common variable immunodeficiency

    Benjamin Gathmann;Nizar Mahlaoui;Laurence Gérard;Eric Oksenhendler

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Human genetic and immunological determinants of critical COVID-19 pneumonia

    Unknown

  • Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

    Tanya I Coulter;Anita Chandra;Chris M Bacon;Judith Babar

  • Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

    Charlotte Schwab;Annemarie Gabrysch;Peter Olbrich;Virginia Patiño

  • Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib

    V. Koneti Rao;Sharon Webster;Virgil A. S. H. Dalm;Anna Šedivá

  • Primary Sjögren syndrome in the paediatric age: a multicentre survey.

    Rolando Cimaz;Annachiara Casadei;Carlos Rose;Jirina Bartunkova

  • Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry

    Maria Elena Maccari;Hassan Abolhassani;Hassan Abolhassani;Asghar Aghamohammadi;Alessandro Aiuti

  • Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI).

    Milena Sokolowska;Zuzanna M. Lukasik;Zuzanna M. Lukasik;Ioana Agache;Cezmi A. Akdis

  • AIRE deficiency in thymus of 2 patients with Omenn syndrome

    Patrizia Cavadini;William Vermi;Fabio Facchetti;Stefania Fontana

  • Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations.

    Julian Thalhammer;Gerhard Kindle;Alexandra Nieters;Stephan Rusch

  • Gliadin fragments induce phenotypic and functional maturation of human dendritic cells.

    Lenka Palová-Jelínková;Daniela Rozková;Barbara Pecharová;Jirina Bártová

  • AIRE deficiency in thymus of 2 patients with Omenn syndrome

    Unknown

  • SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

    Vanessa Sancho-Shimizu;Petter Brodin;Aurélie Cobat;Aurélie Cobat;Aurélie Cobat;Catherine M Biggs

  • New and recurrent gain-of-function STAT1 mutations in patients with chronic mucocutaneous candidiasis from Eastern and Central Europe

    Beáta Soltész;Beáta Tóth;Nadejda Shabashova;Anastasia Bondarenko

  • Managing childhood allergies and immunodeficiencies during respiratory virus epidemics - The 2020 COVID-19 pandemic: A statement from the EAACI-section on pediatrics.

    Helen A. Brough;Omer Kalayci;Anna Sediva;Eva Untersmayr

  • Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

    Zuzana Parackova;Irena Zentsova;Marketa Bloomfield;Petra Vrabcova

  • Anti-N-methyl-D-aspartate receptor encephalitis: the clinical course in light of the chemokine and cytokine levels in cerebrospinal fluid

    Zuzana Liba;Jana Kayserova;Martin Elisak;Petr Marusic

  • Impaired Toll-like receptor 8–mediated IL-6 and TNF-α production in antigen-presenting cells from patients with X-linked agammaglobulinemia

    Klára Sochorová;Rudolf Horváth;Daniela Rožková;Jiří Litzman

  • X-linked agammaglobulinemia (XLA): Phenotype, diagnosis, and therapeutic challenges around the world

    Zeinab A. El-Sayed;Irina Abramova;Juan Carlos Aldave;Waleed Al-Herz

  • Occurrence of B-cell lymphomas in patients with activated phosphoinositide 3-kinase δ syndrome

    Sven Kracker;James Curtis;Mohammad A.A. Ibrahim;Anna Sediva

  • Anti-CD20 (rituximab) treatment for atopic eczema.

    Anna Šedivá;Jana Kayserová;Eva Vernerová;Andrea Poloučková

Frequent Co-Authors

Radek Spisek
Radek Spisek Sotio (Czechia)
Bodo Grimbacher
Bodo Grimbacher University of Freiburg
Klaus Warnatz
Klaus Warnatz University of Freiburg
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Stephan Ehl
Stephan Ehl University of Freiburg
Milan Macek
Milan Macek Charles University
Conleth Feighery
Conleth Feighery Trinity College Dublin
Despina Moshous
Despina Moshous Necker-Enfants Malades Hospital
Eva Untersmayr
Eva Untersmayr Medical University of Vienna
Filomeen Haerynck
Filomeen Haerynck Ghent University

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