Filomeen Haerynck

Overview

Best Publications

• Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

  Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  2660
  Citations

• Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

  Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  2199
  Citations

• Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

  Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  592
  Citations

• Human genetic and immunological determinants of critical COVID-19 pneumonia

  Unknown

  588
  Citations

• Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

  Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  443
  Citations

• Multisystem inflammatory syndrome in children related to COVID-19: a systematic review.

  Levi Hoste;Ruben Van Paemel;Filomeen Haerynck

  436
  Citations

• Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP-deficiency) versus type 2 (XLP-2/XIAP-deficiency)

  Jana Pachlopnik Schmid;Jana Pachlopnik Schmid;Danielle Canioni;Despina Moshous;Despina Moshous;Fabien Touzot

  399
  Citations

• Genes associated with common variable immunodeficiency: one diagnosis to rule them all?

  Delfien J A Bogaert;Melissa Dullaers;Bart N Lambrecht;Karim Y Vermaelen

  313
  Citations

• Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study

  Federica Barzaghi;Laura Cristina Amaya Hernandez;Benedicte Neven;Silvia Ricci

  293
  Citations

• The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

  Unknown

  263
  Citations

• Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

  Unknown

  208
  Citations

• Familial Mediterranean Fever Mutations Lift the Obligatory Requirement for Microtubules in Pyrin Inflammasome Activation

  Hanne Van Gorp;Pedro Henrique Viana Saavedra;Nathalia Moraes de Vasconcelos;Nina Van Opdenbosch

  178
  Citations

• Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score

  Victoria Katharina Tesch;Hassan Abolhassani;Hassan Abolhassani;Bella Shadur;Bella Shadur;Joachim Zobel

  160
  Citations

• Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation

  Aude Magerus-Chatinet;Bénédicte Neven;Marie Claude Stolzenberg;Cécile Daussy

  159
  Citations

• Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations.

  Julian Thalhammer;Gerhard Kindle;Alexandra Nieters;Stephan Rusch

  158
  Citations

• Autoantibodies against type I IFNs in patients with critical influenza pneumonia

  Unknown

  157
  Citations

• SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

  Vanessa Sancho-Shimizu;Petter Brodin;Aurélie Cobat;Aurélie Cobat;Aurélie Cobat;Catherine M Biggs

  139
  Citations

• Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.

  Yehudi Bloch;Laura Bouchareychas;Laura Bouchareychas;Romain Merceron;Katarzyna Składanowska

  126
  Citations

• Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis.

  Scott B Drutman;Filomeen Haerynck;Franklin L Zhong;David Hum

  124
  Citations

• X-linked agammaglobulinemia (XLA): Phenotype, diagnosis, and therapeutic challenges around the world

  Zeinab A. El-Sayed;Irina Abramova;Juan Carlos Aldave;Waleed Al-Herz

  118
  Citations

• Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.

  Béziat;Tavernier Sj;Chen Yh;Ma Cs

  108
  Citations

• Chronic and Invasive Fungal Infections in a Family with CARD9 Deficiency.

  Ana Karina Alves de Medeiros;Evelyn Lodewick;Delfien J A Bogaert;Filomeen Haerynck

  108
  Citations

• TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

  Levi Hoste;Lisa Roels;Leslie Naesens;Victor Bosteels

  74
  Citations

• Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.

  Jozefien Declercq;Karel F A Van Damme;Elisabeth De Leeuw;Bastiaan Maes

  70
  Citations