Aurélie Cobat

Overview

Best Publications

• Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

  Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  2660
  Citations

• Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

  Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  2199
  Citations

• Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants.

  Aziz Belkadi;Alexandre Bolze;Yuval Itan;Aurélie Cobat;Aurélie Cobat

  726
  Citations

• Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

  Anne Puel;Anne Puel;Rainer Döffinger;Angels Natividad;Angels Natividad;Maya Chrabieh;Maya Chrabieh

  680
  Citations

• Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

  Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  592
  Citations

• Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells

  Ludovic de Beaucoudrey;Ludovic de Beaucoudrey;Anne Puel;Anne Puel;Orchidée Filipe-Santos;Orchidée Filipe-Santos;Aurélie Cobat;Aurélie Cobat

  496
  Citations

• Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries

  Ludovic de Beaucoudrey;Arina Samarina;Arina Samarina;Arina Samarina;Jacinta Bustamante;Jacinta Bustamante;Aurélie Cobat;Aurélie Cobat

  443
  Citations

• X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19.

  Takaki Asano;Bertrand Boisson;Bertrand Boisson;Bertrand Boisson;Fanny Onodi;Daniela Matuozzo;Daniela Matuozzo

  403
  Citations

• Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

  Alexandra Y. Kreins;Alexandra Y. Kreins;Michael J. Ciancanelli;Satoshi Okada;Xiao Fei Kong

  352
  Citations

• Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia

  Bertrand Boisson;Emmanuel Laplantine;Kerry Dobbs;Aurélie Cobat

  279
  Citations

• Loss of B Cells in Patients with Heterozygous Mutations in IKAROS

  Hye Sun Kuehn;Bertrand Boisson;Charlotte Cunningham-Rundles;Janine Reichenbach

  268
  Citations

• Exome and genome sequencing for inborn errors of immunity

  Isabelle Meyts;Barbara Bosch;Barbara Bosch;Alexandre Bolze;Bertrand Boisson;Bertrand Boisson;Bertrand Boisson

  232
  Citations

• A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

  Jean-Laurent Casanova;Helen C. Su;Covid Human Genetic Effort

  230
  Citations

• Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.

  Paul Bastard;Paul Bastard;Paul Bastard;Eleftherios Michailidis;Hans-Heinrich Hoffmann;Marwa Chbihi;Marwa Chbihi

  222
  Citations

• Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

  Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Stéphanie Boisson-Dupuis;Noe Ramirez-Alejo;Zhi Li;Zhi Li;Etienne Patin;Etienne Patin

  201
  Citations

• A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.

  Vinicius M. Fava;Vinicius M. Fava;Jérémy Manry;Jérémy Manry;Aurélie Cobat;Aurélie Cobat;Marianna Orlova;Marianna Orlova

  198
  Citations

• Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis

  Aurelie Cobat;Aurelie Cobat;Caroline J. Gallant;Leah Simkin;Gillian F. Black

  194
  Citations

• Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds.

  Carolina Prando;Arina Samarina;Jacinta Bustamante;Stéphanie Boisson-Dupuis

  178
  Citations

• Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

  Nicholas Hernandez;Giorgia Bucciol;Leen Moens;Jérémie Le Pen

  173
  Citations

• Human HOIP and LUBAC de!ciency underlies autoin"ammation, immunode!ciency, amylopectinosis, and lymphangiectasia

  Bertrand Boisson;Emmanuel Laplantine;Kerry Dobbs;Aurélie Cobat

  0
  Citations