Jürgen Kopitz mostly deals with Biochemistry, Cell biology, Cell culture, Lipofuscin and Ganglioside. His Biochemistry research focuses on Lipid peroxidation, Retinal pigment epithelium, Lectin, Glycan and Enzyme. His Cell biology research includes themes of Autophagy, Membrane and Lysosome.
As part of one scientific family, he deals mainly with the area of Cell culture, narrowing it down to issues related to the Intracellular, and often In vitro, Phagocytosis, Protease, Oxidative stress and Lysosomal lumen. His Ganglioside research is multidisciplinary, incorporating elements of Cell, Lipid raft, Cell growth and Sialidase, Neuraminidase. His biological study spans a wide range of topics, including Molecular biology, Apoptosis and Galectin.
Jürgen Kopitz spends much of his time researching Biochemistry, Cell biology, Galectin, Molecular biology and Lectin. His study in Enzyme, Ganglioside, Lipofuscin, Glycoprotein and Lysosome falls under the purview of Biochemistry. His Cell biology research is multidisciplinary, relying on both Retinal pigment epithelium, Cell culture, Sialidase and Autophagy.
His Galectin study incorporates themes from Cell, Galectin-1, Stereochemistry, Binding site and Effector. The various areas that Jürgen Kopitz examines in his Molecular biology study include Small intestine, Gene, Frameshift mutation, Exon and Ornithine decarboxylase. His work in Lectin tackles topics such as Glycan which are related to areas like Glycosylation, Glycoconjugate and Computational biology.
The scientist’s investigation covers issues in Cell biology, Galectin, Microsatellite instability, Lectin and Glycan. Cell, Cell culture and Growth inhibition is closely connected to Stable isotope labeling by amino acids in cell culture in his research, which is encompassed under the umbrella topic of Cell biology. His Galectin research integrates issues from Biophysics, Transcription factor, PAX6, Lens protein and Effector.
His research on Lectin concerns the broader Biochemistry. His biological study spans a wide range of topics, including Epitope and Tn antigen. Jürgen Kopitz has included themes like Glycosylation and Glycosphingolipid in his Glycan study.
Galectin, Lectin, Glycan, Biophysics and Effector are his primary areas of study. His Galectin study is focused on Cell biology in general. His Cell biology study combines topics in areas such as Crystallin, Sialic acid, Glycoprotein and Sialidase.
His research is interdisciplinary, bridging the disciplines of Ganglioside and Lectin. His Glycan study integrates concerns from other disciplines, such as Glycosylation and Communication. His Effector research incorporates themes from Protein engineering and Cell growth.
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Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin.
Florian Schütt;Sallyanne Davies;Jürgen Kopitz;Frank G. Holz.
Investigative Ophthalmology & Visual Science (2000)
Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin.
F G Holz;F Schütt;J Kopitz;G E Eldred.
Investigative Ophthalmology & Visual Science (1999)
Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture.
Jürgen Kopitz;Carolina von Reitzenstein;Maria Burchert;Michael Cantz.
Journal of Biological Chemistry (1998)
Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.
Jürgen Kopitz;Carolina von Reitzenstein;Sabine André;Herbert Kaltner.
Journal of Biological Chemistry (2001)
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium.
Florian Schutt;Marion Bergmann;Frank G Holz;Jurgen Kopitz.
Investigative Ophthalmology & Visual Science (2003)
Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes.
Jürgen Kopitz;Gunn Kisen;Paul B. Gordon;Peter Bohley.
Journal of Cell Biology (1990)
Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration.
M. Bergmann;F. Schütt;F.G. Holz;J. Kopitz.
The FASEB Journal (2004)
Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Sabine André;Hugo Sanchez-Ruderisch;Hiroaki Nakagawa;Malte Buchholz.
FEBS Journal (2007)
Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a Glycoprotein and Cell‐Surface Glycoconjugates and Selectivity among Human Adhesion/Growth‐Regulatory Galectins
Sabine André;Francesco Sansone;Herbert Kaltner;Alessandro Casnati.
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells
Jürgen Kopitz;Sabine André;Carolina Von Reitzenstein;Kees Versluis.
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