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Biology and Biochemistry

D-Index
62
Citations
9432
World Ranking
11066
National Ranking
792

Overview

Roland Penzel is affiliated with University Hospital Heidelberg in Germany and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research is strongly focused on oncology and cancer research, with significant work in pulmonary and respiratory medicine, pathology and forensic medicine, and surgery.

The main topics addressed in their publications include cancer genomics and diagnostics, lung cancer treatments and mutations, pancreatic and hepatic oncology research, healthcare cost, quality, and practices, genetic factors in colorectal cancer, lung cancer research studies, and cancer immunotherapy and biomarkers.

Some of Roland Penzel's recent notable papers include:

  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers, 2021, Cancer Discovery
  • Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers, 2022, Annals of Oncology
  • Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity, 2022, Nature Communications
  • Risk stratification of EGFR+ lung cancer diagnosed with panel-based next-generation sequencing, 2020, Lung Cancer
  • The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma, 2021, ESMO Open

Frequent co-authors collaborating with Roland Penzel include:

  • Albrecht Stenzinger
  • Peter Schirmacher
  • Daniel Kazdal
  • Anna-Lena Volckmar
  • Jan Budczies

Their work has been published repeatedly in venues such as:

  • Die Pathologie
  • Lung Cancer
  • Genes Chromosomes and Cancer
  • Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  • Cancer Discovery

Roland Penzel's research contributions span across 31 publications in Medicine and 11 publications in Biochemistry, Genetics and Molecular Biology. Within subfields, the focus includes Oncology (10 publications), Cancer Research (8 publications), Pulmonary and Respiratory Medicine (5 publications), Pathology and Forensic Medicine (4 publications), and Surgery (3 publications).

Best Publications

  • Tenascin C and annexin II expression in the process of pancreatic carcinogenesis.

    I Esposito;R Penzel;M Chaib-Harrireche;U Barcena

  • NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

    Christoph Heining;Peter Horak;Sebastian Uhrig;Paula L Codo

  • Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

    Peter Horak;Christoph Heining;Simon Kreutzfeldt;Barbara Hutter

  • Histologic classification of thymic epithelial tumors: comparison of established classification schemes.

    Ralf J. Rieker;Josef Hoegel;Alicia Morresi-Hauf;Walter J. Hofmann

  • Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians

    Michael Allgäuer;Jan Budczies;Jan Budczies;Petros Christopoulos;Volker Endris

  • Precision oncology based on omics data: The NCT Heidelberg experience.

    Peter Horak;Barbara Klink;Christoph Heining;Stefan Gröschel

  • Application of a BRAF V600E Mutation-specific Antibody for the Diagnosis of Hairy Cell Leukemia

    Mindaugas Andrulis;Roland Penzel;Wilko Weichert;Andreas von Deimling

  • Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing.

    Volker Endris;Roland Penzel;Arne Warth;Alexander Muckenhuber

  • Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas

    Moritz Jesinghaus;Björn Konukiewitz;Gisela Keller;Matthias Kloor

  • Size matters: Dissecting key parameters for panel-based tumor mutational burden analysis.

    Ivo Buchhalter;Ivo Buchhalter;Eugen Rempel;Volker Endris;Michael Allgäuer

  • Molecular heterogeneity of TFE3 activation in renal cell carcinomas.

    Stephan Macher-Goeppinger;Stephan Macher-Goeppinger;Wilfried Roth;Nina Wagener;Markus Hohenfellner

  • Genome-wide analysis of pediatric-type follicular lymphoma reveals low genetic complexity and recurrent alterations of TNFRSF14 gene

    Janine Schmidt;Shunyou Gong;Teresa Marafioti;Barbara Mankel

  • EML4-ALK fusion variant V3 is a high-risk feature conferring accelerated metastatic spread, early treatment failure and worse overall survival in ALK + non-small cell lung cancer

    Petros Christopoulos;Volker Endris;Farastuk Bozorgmehr;Mei Elsayed

  • Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy

    Arne Warth;Stephan Macher-Goeppinger;Thomas Muley;Michael Thomas

  • Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer.

    Stephan Singer;Mona Malz;Esther Herpel;Arne Warth

  • Decentral gene expression analysis for ER+/Her2− breast cancer: results of a proficiency testing program for the EndoPredict assay

    Carsten Denkert;Ralf Kronenwett;Werner Schlake;Kerstin Bohmann

  • SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma

    M Trautmann;E Sievers;S Aretz;D Kindler

  • EGFR mutation detection in NSCLC—assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC

    Roland Penzel;Christine Sers;Yuan Chen;Ulrich Lehmann-Mühlenhoff

  • EGFR, KRAS, BRAF and ALK gene alterations in lung adenocarcinomas: patient outcome, interplay with morphology and immunophenotype.

    Arne Warth;Roland Penzel;Heike Lindenmaier;Regine Brandt

  • Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma.

    Hendrik Bläker;Walter J. Hofmann;Ralf J. Rieker;Roland Penzel

Frequent Co-Authors

Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Albrecht Stenzinger
Albrecht Stenzinger Heidelberg University
Wilko Weichert
Wilko Weichert Technical University of Munich
Benedikt Brors
Benedikt Brors German Cancer Research Center
Hanno Glimm
Hanno Glimm TU Dresden
Felix J.F. Herth
Felix J.F. Herth Heidelberg University
Manfred Dietel
Manfred Dietel Charité - University Medicine Berlin
Barbara Hutter
Barbara Hutter German Cancer Research Center
Roland Eils
Roland Eils Charité - University Medicine Berlin

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