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Magnus von Knebel Doeberitz

Magnus von Knebel Doeberitz

D-Index & Metrics

Medicine

D-Index
98
Citations
29717
World Ranking
9016
National Ranking
506

Overview

Magnus von Knebel Doeberitz is affiliated with Heidelberg University in Germany, contributing extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on genetic factors in colorectal cancer, cancer genomics and diagnostics, and colorectal cancer screening and detection. Additional topics in their work include cervical cancer and HPV research, colorectal cancer treatments and studies, cancer immunotherapy and biomarkers, and multiple and secondary primary cancers.

The scientist has published numerous papers, with several appearing in prominent venues. Notable publications include:

  • European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender, 2020, British Journal of Surgery
  • A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial, 2020, Clinical Cancer Research
  • The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution, 2020, Nature Communications
  • Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model, 2021, Gastroenterology
  • Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome, 2020, Gastroenterology

Frequent coauthors with whom the scientist has collaborated include Matthias Kloor, Aysel Ahadova, Robert Hüneburg, Toni T. Seppälä, and Jukka-Pekka Mecklin. This network of collaborators has contributed to substantial progress in related fields.

Publications by Magnus von Knebel Doeberitz have appeared most often in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • International Journal of Cancer
  • Cancers
  • Journal of Clinical Medicine

Their research areas are further broken down into subfields such as pathology and forensic medicine, oncology, cancer research, epidemiology, and molecular biology. This multidisciplinary approach facilitates comprehensive investigations into the molecular mechanisms and clinical implications of cancer and related diseases.

Best Publications

  • Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri

    Ruediger Klaes;Tibor Friedrich;Dimitry Spitkovsky;Ruediger Ridder

  • Potential of fecal microbiota for early‐stage detection of colorectal cancer

    Georg Zeller;Julien Tap;Anita Y Voigt;Shinichi Sunagawa

  • Comprehensive control of human papillomavirus infections and related diseases.

    F. Xavier Bosch;Thomas R. Broker;David Forman;Anna Barbara Moscicki

  • p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia.

    Rüdiger Klaes;Axel Benner;Tibor Friedrich;Rüdiger Ridder

  • Systematic Review of Genomic Integration Sites of Human Papillomavirus Genomes in Epithelial Dysplasia and Invasive Cancer of the Female Lower Genital Tract

    Nicolas Wentzensen;Svetlana Vinokurova;Magnus von Knebel Doeberitz

  • Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes.

    Ruediger Klaes;Stefan M. Woerner;Ruediger Ridder;Nicolas Wentzensen

  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Mev Dominguez-Valentin;Julian R. Sampson;Toni T. Seppälä;Sanne W. ten Broeke

  • Type-dependent integration frequency of human papillomavirus genomes in cervical lesions

    Svetlana Vinokurova;Nicolas Wentzensen;Irene Kraus;Ruediger Klaes

  • Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

    Yvette Schwitalle;Matthias Kloor;Susanne Eiermann;Michael Linnebacher

  • Correlation of Modified Human Papilloma Virus Early Gene Expression with Altered Growth Properties in C4-1 Cervical Carcinoma Cells

    Magnus von Knebel Doeberitz;Tilman Oltersdorf;Elisabeth Schwarz;Lutz Gissmann

  • Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome

    Christoph Engel;Markus Loeffler;Verena Steinke;Nils Rahner

  • Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium

    Jens Plaschke;Christoph Engel;Stefan Krüger;Elke Holinski-Feder

  • A systematic review of humoral immune responses against tumor antigens

    Miriam Reuschenbach;Magnus von Knebel Doeberitz;Nicolas Wentzensen

  • Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV e6-e7 anti-sense RNA

    Magnus von Knebel Doeberitz;Claudia Rittmüller;Harald Zur Hausen;Matthias dürst

  • An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

    Milena Traykova-Brauch;Kai Schönig;Oliver Greiner;Tewfik Miloud

  • Mutational activation of the β-catenin proto-oncogene is a common event in the development of Wilms' tumors

    Robert Koesters;Ruediger Ridder;Annette Kopp-Schneider;David Betts

  • Screening for Cervical Cancer Precursors With p16/Ki-67 Dual-Stained Cytology: Results of the PALMS Study

    Hans Ikenberg;Christine Bergeron;Dietmar Schmidt;Henrik Griesser

  • Glucocorticoid Cotreatment Induces Apoptosis Resistance toward Cancer Therapy in Carcinomas

    Ingrid Herr;Esat Ucur;Esat Ucur;Kerstin Herzer;Stella Okouoyo;Stella Okouoyo

  • Biomarkers in Cervical Cancer Screening

    Nicolas Wentzensen;Magnus von Knebel Doeberitz

  • Frameshift peptide‐derived T‐cell epitopes: A source of novel tumor‐specific antigens

    Michael Linnebacher;Johannes Gebert;Wolfgang Rudy;Stefan Woerner

Frequent Co-Authors

Matthias Kloor
Matthias Kloor University Hospital Heidelberg
Christoph Engel
Christoph Engel Leipzig University
Axel Benner
Axel Benner German Cancer Research Center
Jürgen Weitz
Jürgen Weitz TU Dresden
Christian Herfarth
Christian Herfarth Heidelberg University
Peer Bork
Peer Bork European Molecular Biology Laboratory
Nicolas Wentzensen
Nicolas Wentzensen National Institutes of Health
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Hans F. A. Vasen
Hans F. A. Vasen Leiden University
Jukka-Pekka Mecklin
Jukka-Pekka Mecklin University of Jyväskylä

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