World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
11403
World Ranking
12646
National Ranking
470

Overview

Farzad Pakdel is affiliated with the University of Rennes in France and has a research focus primarily within the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their scholarly output consists of 21 publications in biochemistry-related areas and 9 in medical sciences.

Pakdel's subfields of study encompass Molecular Biology, Genetics, Oncology, Pathology and Forensic Medicine, and Health, Toxicology and Mutagenesis. These subfields showcase a multidisciplinary approach bridging molecular mechanisms and clinical implications.

The main topics covered in Pakdel's research include:

  • Estrogen and related hormone effects
  • Advanced Breast Cancer Therapies
  • Phytoestrogen effects and research
  • Genomics, phytochemicals, and oxidative stress
  • Breast Cancer Treatment Studies
  • HER2/EGFR in Cancer Research
  • FOXO transcription factor regulation

Frequent coauthors of Pakdel include Gilles Flouriot (6 joint publications), François Ferrière (5), Frédéric Percevault (4), Léa Clusan (3), and Pascale Le Goff (3). This collaborative network supports research diversity and depth.

Most of the research contributions are published in the International Journal of Molecular Sciences, which features five of their papers. Other venues include Environmental Science and Pollution Research, Life Science Alliance, Molecular and Cellular Endocrinology, and Phytotherapy Research.

Representative recent papers authored or coauthored by Pakdel are:

  • "The Role of Estrogen Receptors in Health and Disease", 2023, International Journal of Molecular Sciences
  • "A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer", 2023, International Journal of Molecular Sciences
  • "A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses", 2021, International Journal of Molecular Sciences
  • "Apigenin, a Partial Antagonist of the Estrogen Receptor (ER), Inhibits ER-Positive Breast Cancer Cell Proliferation through Akt/FOXM1 Signaling", 2021, International Journal of Molecular Sciences
  • "Interference with zinc homeostasis and oxidative stress induction as probable mechanisms for cadmium-induced embryo-toxicity in zebrafish", 2022, Environmental Science and Pollution Research

Best Publications

  • Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.

    Helle Raun Andersen;Anna-Maria Andersson;Steven F. Arnold;Herman Autrup

  • Molecular Characterization of Three Estrogen Receptor Forms in Zebrafish: Binding Characteristics, Transactivation Properties, and Tissue Distributions

    Arnaud Menuet;Elisabeth Pellegrini;Isabelle Anglade;Odile Blaise

  • Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish.

    Ksenia Cheshenko;Farzad Pakdel;Helmut Segner;Olivier Kah

  • Aromatase in the brain of teleost fish: expression, regulation and putative functions.

    Nicolas Diotel;Yann Le Page;Karen Mouriec;Sok-Keng Tong

  • Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression.

    G Flouriot;F Pakdel;B Ducouret;Y Valotaire

  • Identification of aromatase-positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish.

    Elisabeth Pellegrini;Karen Mouriec;Isabelle Anglade;Arnaud Menuet

  • Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene.

    Arnaud Menuet;Elisabeth Pellegrini;François Brion;Marie-Madeleine Gueguen

  • Two complementary bioassays for screening the estrogenic potency of xenobiotics: recombinant yeast for trout estrogen receptor and trout hepatocyte cultures

    F Petit;P Le Goff;JP Cravedi;Y Valotaire

  • Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression

    Gilles Flouriot;Farzad Pakdel;Yves Valotaire

  • Analysis of the estrogen regulation of the zebrafish estrogen receptor (ER) reveals distinct effects of ERalpha, ERbeta1 and ERbeta2.

    A Menuet;Y Le Page;O Torres;L Kern

  • Identification and Estrogen Induction of Two Estrogen Receptors (ER) Messenger Ribonucleic Acids in the Rainbow Trout Liver: Sequence Homology with other ERs

    Farzad Pakdel;Catherine Le Guellec;Colette Vaillant;Marie Gaëlle Le Roux

  • In vivo estrogen induction of hepatic estrogen receptor mRNA and correlation with vitellogenin mRNA in rainbow trout

    Farzad Pakdel;Sylvie Féon;Florence Le Gac;Françoise Le Menn

  • Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains.

    Raphaël Métivier;Graziella Penot;Gilles Flouriot;Farzad Pakdel

  • Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methods

    Rémy Le Guevel;Farzad Pakdel

  • Distribution of aromatase mRNA and protein in the brain and pituitary of female rainbow trout: Comparison with estrogen receptor α

    Arnaud Menuet;Isabelle Anglade;Remy Le Guevel;Elisabeth Pellegrini

  • Relationships between aromatase and estrogen receptors in the brain of teleost fish

    Elisabeth Pellegrini;Arnaud Menuet;Christèle Lethimonier;Fátima Adrio

  • Phytochemicals Targeting Estrogen Receptors: Beneficial Rather Than Adverse Effects?

    Sylvain Lecomte;Florence Demay;François Ferrière;Farzad Pakdel

  • A mineralocorticoid-like receptor in the rainbow trout, Oncorhynchus mykiss: cloning and characterization of its steroid binding domain.

    Laurent Colombe;Alexis Fostier;Nicolas Bury;Farzad Pakdel

  • Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination.

    F Pakdel;B S Katzenellenbogen

  • Profiling of benzophenone derivatives using fish and human estrogen receptor-specific in vitro bioassays.

    José-Manuel Molina-Molina;Aurélie Escande;Arnaud Pillon;Elena Gomez

Frequent Co-Authors

Olivier Kah
Olivier Kah University of Rennes
François Brion
François Brion French National Institute for Industrial Environment and Risks
Patrick Balaguer
Patrick Balaguer University of Montpellier
Bon-chu Chung
Bon-chu Chung China Medical University
Helmut Segner
Helmut Segner University of Bern
Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign
Vincent Cavaillès
Vincent Cavaillès Institute of Cancer Research of Montpellier
Rik I.L. Eggen
Rik I.L. Eggen ETH Zurich
Michel Samson
Michel Samson University of Rennes

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Farzad Pakdel

Trending Scientists