François Brion

Best Publications

• Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish.

  Unknown

  810
  Citations

• Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio)

  François Brion;C.R. Tyler;Xavier Palazzi;B. Laillet

  532
  Citations

• Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management.

  Rolf Altenburger;Selim Ait-Aissa;Philipp Antczak;Thomas Backhaus

  365
  Citations

• Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive.

  Beate I. Escher;Selim Aїt-Aїssa;Peter A. Behnisch;Werner Brack;Werner Brack

  295
  Citations

• Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their Contribution to effects in surface water

  Peta A. Neale;Rolf Altenburger;Selim Aït-Aïssa;François Brion

  236
  Citations

• In vitro and in vivo estrogenic activity of BPA, BPF and BPS in zebrafish-specific assays

  Vincent Le Fol;Selim Aït-Aïssa;Manoj Sonavane;Jean-Marc Porcher

  228
  Citations

• Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.

  François Brion;Yann Le Page;Benjamin Piccini;Olivier Cardoso

  216
  Citations

• European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters

  Zuzana Toušová;Peter Oswald;Jaroslav Slobodník;Luděk Bláha

  213
  Citations

• Adverse effects in wild fish living downstream from pharmaceutical manufacture discharges

  Unknown

  210
  Citations

• Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams.

  Peta A. Neale;Nicole A. Munz;Selim Aїt-Aїssa;Rolf Altenburger

  189
  Citations

• Inhibition of rainbow trout (Oncorhynchus mykiss) P450 aromatase activities in brain and ovarian microsomes by various environmental substances.

  Unknown

  181
  Citations

• Development of quantitative vitellogenin-ELISAs for fish test species used in endocrine disruptor screening.

  Bente M. Nilsen;Karin Berg;Janne K. Eidem;Sven-Inge Kristiansen

  176
  Citations

• Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

  Raquel N. Carvalho;Augustine Arukwe;Selim Ait-Aissa;Anne Bado-Nilles

  148
  Citations

• Identification of synthetic steroids in river water downstream from pharmaceutical manufacture discharges based on a bioanalytical approach and passive sampling.

  Nicolas Creusot;Selim Aït-Aïssa;Nathalie Tapie;Patrick Pardon

  148
  Citations

• Mixture effects in samples of multiple contaminants - An inter-laboratory study with manifold bioassays.

  Rolf Altenburger;Martin Scholze;Wibke Busch;Beate Escher

  146
  Citations

• Induction of Fish Vitellogenin and Alterations in Testicular Structure: Preliminary Results of Estrogenic Effects in Chub (Leuciscus cephalus)

  Patrick Flammarion;François Brion;Marc Babut;Jeanne Garric

  146
  Citations

• Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line

  Nathalie Laville;Patrick Balaguer;François Brion;Nathalie Hinfray

  126
  Citations

• Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor.

  Ksenia Cheshenko;Francois Brion;Yann Le Page;Nathalie Hinfray

  116
  Citations

• Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis

  Tobias Schulze;Marijan Ahel;Jörg Ahlheim;Selim Aït-Aïssa

  106
  Citations

• Cell-specific biotransformation of benzophenone-2 and bisphenol-s in zebrafish and human in vitro models used for toxicity and estrogenicity screening.

  Vincent Le Fol;Vincent Le Fol;Selim Aït-Aïssa;Nicolas Cabaton;Nicolas Cabaton;Laurence Dolo;Laurence Dolo

  99
  Citations