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Susumu Uchiyama

Susumu Uchiyama

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10397
World Ranking
15103
National Ranking
1066

Overview

Susumu Uchiyama is affiliated with Osaka University in Japan and has a research focus primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with a significant volume of work also pertaining to Medicine.

Their scholarly output spans a range of subfields including Molecular Biology, Genetics, Radiology, Nuclear Medicine and Imaging, Infectious Diseases, and Oncology.

The main research topics addressed in their work encompass:

  • Protein purification and stability
  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Viral gastroenteritis research and epidemiology
  • CAR-T cell therapy research
  • Wnt/β-catenin signaling in development and cancer

Uchiyama's recent publications demonstrate a focus on biotechnological methods and therapeutic research:

  • "Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections," 2020, published in Progress in Retinal and Eye Research
  • "Comprehensive Size Distribution and Composition Analysis of Adeno-Associated Virus Vector by Multiwavelength Sedimentation Velocity Analytical Ultracentrifugation," 2021, published in Journal of Pharmaceutical Sciences
  • "Characterization of Adeno-Associated Virus Capsid Proteins with Two Types of VP3-Related Components by Capillary Gel Electrophoresis and Mass Spectrometry," 2021, published in Human Gene Therapy
  • "Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain," 2022, published in Science Translational Medicine
  • "Effect of UVC Irradiation on the Oxidation of Histidine in Monoclonal Antibodies," 2020, published in Scientific Reports

Frequently, the scientist collaborates with other researchers including Tetsuo Torisu, Takahiro Maruno, Yuki Yamaguchi, Mitsuko Fukuhara, and Yasuo Tsunaka. These collaborations are reflected in the body of published work.

The work of Uchiyama is found across several key scientific publication venues, with a notable number of contributions to the Journal of Pharmaceutical Sciences. Other frequent venues include bioRxiv (Cold Spring Harbor Laboratory), Molecular Therapy - Methods & Clinical Development, Scientific Reports, and Analytical Chemistry.

Best Publications

  • Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

    Zhikuan Zhang;Umeharu Ohto;Takuma Shibata;Elena Krayukhina

  • Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

    Umeharu Ohto;Takuma Shibata;Hiromi Tanji;Hanako Ishida

  • Target Antigen Density Governs the Efficacy of Anti–CD20-CD28-CD3 ζ Chimeric Antigen Receptor–Modified Effector CD8+ T Cells

    Keisuke Watanabe;Seitaro Terakura;Anton C. Martens;Tom van Meerten

  • Protein encapsulation within synthetic molecular hosts

    Daishi Fujita;Kosuke Suzuki;Sota Sato;Maho Yagi-Utsumi;Maho Yagi-Utsumi

  • Remodeling of gp41‐C34 Peptide Leads to Highly Effective Inhibitors of the Fusion of HIV‐1 with Target Cells

    Akira Otaka;Miki Nakamura;Daisuke Nameki;Eiichi Kodama

  • Magnetization Process of Exchange-Coupled Ferrimagnetic Double-Layered Films

    Tadashi Kobayashi;Hisao Tsuji;Shigeru Tsunashima;Susumu Uchiyama

  • Structural basis for semaphorin signalling through the plexin receptor.

    Terukazu Nogi;Norihisa Yasui;Norihisa Yasui;Emiko Mihara;Yukiko Matsunaga

  • Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

    Yasuaki Kabe;Takanori Nakane;Ikko Koike;Tatsuya Yamamoto

  • SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation

    Kiwamu Takemoto;Tomoki Matsuda;Tomoki Matsuda;Naoki Sakai;Naoki Sakai;Donald Fu

  • H2A.Z and H3.3 histone variants affect nucleosome structure: biochemical and biophysical studies.

    Amit Thakar;Pooja Gupta;Toyotaka Ishibashi;Ron Finn

  • Behavior of Monoclonal Antibodies: Relation Between the Second Virial Coefficient (B 2) at Low Concentrations and Aggregation Propensity and Viscosity at High Concentrations

    Shuntaro Saito;Jun Hasegawa;Naoki Kobayashi;Naoyuki Kishi

  • The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen.

    Joyce A. Cartagena;Sachihiro Matsunaga;Motoaki Seki;Daisuke Kurihara

  • Effects of Syringe Material and Silicone Oil Lubrication on the Stability of Pharmaceutical Proteins

    Elena Krayukhina;Kouhei Tsumoto;Susumu Uchiyama;Kiichi Fukui

  • Nucleolin functions in nucleolus formation and chromosome congression.

    Nan Ma;Sachihiro Matsunaga;Hideaki Takata;Rika Ono-Maniwa

  • Proteome analysis of human metaphase chromosomes

    Susumu Uchiyama;Shouhei Kobayashi;Hideaki Takata;Takeshi Ishihara

  • Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization

    Umeharu Ohto;Hanako Ishida;Elena Krayukhina;Susumu Uchiyama;Susumu Uchiyama

  • Phase separation of an IgG1 antibody solution under a low ionic strength condition.

    Hirotaka Nishi;Makoto Miyajima;Hiroaki Nakagami;Masanori Noda

  • Structural basis of the interaction between IgG and Fcgamma receptors.

    Koichi Kato;Catherine Sautès-Fridman;Wakako Yamada;Kaoru Kobayashi

  • Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces.

    Satoru Fujimoto;Sachihiro Matsunaga;Masataka Yonemura;Susumu Uchiyama

  • Human nucleolin functions in nucleolus formation and chromosome congression

    Nan Ma;Sachihiro Matsunaga;Hideaki Takata;Susumu Uchiyama

Frequent Co-Authors

Kiichi Fukui
Kiichi Fukui Osaka University
Sachihiro Matsunaga
Sachihiro Matsunaga Tokyo University of Science
Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Shota Nakamura
Shota Nakamura Osaka University
Masaharu Noda
Masaharu Noda National Institute for Basic Biology
Toshiyuki Shimizu
Toshiyuki Shimizu University of Tokyo
Yasuo Igarashi
Yasuo Igarashi Southwest University
Masao Matsuoka
Masao Matsuoka Kumamoto University
Shinichi Takayama
Shinichi Takayama Sanford Burnham Prebys Medical Discovery Institute
Katsumi Maenaka
Katsumi Maenaka Hokkaido University

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