What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Genetics, Drosophila melanogaster, Longevity, Cell biology and Gene.
His study explores the link between Genetics and topics such as Evolutionary biology that cross with problems in Genetics of aging, Gene Alteration, Fertility and Fecundity.
His Drosophila melanogaster study is concerned with the larger field of Biochemistry.
In Longevity, Stephen L. Helfand works on issues like Mutation, which are connected to Regulation of gene expression.
His research in Cell biology intersects with topics in Embryonic stem cell, Downregulation and upregulation, Retrotransposon and Anatomy.
His research in Gene is mostly concerned with Drosophila Protein.
His most cited work include:
- Sirtuin activators mimic caloric restriction and delay ageing in metazoans (1569 citations)
- Sir2 mediates longevity in the fly through a pathway related to calorie restriction (1087 citations)
- Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1. (394 citations)
What are the main themes of his work throughout his whole career to date?
Stephen L. Helfand mainly focuses on Drosophila melanogaster, Genetics, Longevity, Gene and Cell biology.
Stephen L. Helfand has researched Drosophila melanogaster in several fields, including Phenotype and Mutation.
His work deals with themes such as Calorie restriction, Internal medicine, Endocrinology, Metabolism and Signal transduction, which intersect with Longevity.
The Gene study combines topics in areas such as Computational biology and Resveratrol.
He interconnects Glycolysis, Interferon, Downregulation and upregulation and Suppressor in the investigation of issues within Cell biology.
His Drosophila research is multidisciplinary, incorporating perspectives in Cognitive science and Calorie.
He most often published in these fields:
- Drosophila melanogaster (43.81%)
- Genetics (42.86%)
- Longevity (32.38%)
What were the highlights of his more recent work (between 2016-2021)?
- Drosophila melanogaster (43.81%)
- Cell biology (24.76%)
- Internal medicine (10.48%)
In recent papers he was focusing on the following fields of study:
Stephen L. Helfand mostly deals with Drosophila melanogaster, Cell biology, Internal medicine, Endocrinology and Evolutionary biology.
His Drosophila melanogaster study frequently intersects with other fields, such as Metabolism.
His Cell biology research incorporates elements of Interferon and SIRT6.
The concepts of his Internal medicine study are interwoven with issues in Microarray analysis techniques and Gene.
The study incorporates disciplines such as Blood pressure, Insulin resistance and Longevity in addition to Gene.
His study in Evolutionary biology is interdisciplinary in nature, drawing from both Chromatin, Innate immune system, RNA interference and Germline.
Between 2016 and 2021, his most popular works were:
- L1 drives IFN in senescent cells and promotes age-associated inflammation (248 citations)
- LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation (83 citations)
- Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster (30 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Cell biology, Inflammation, Interferon, Derepression and SIRT6.
His studies deal with areas such as Glycolysis, Drosophila melanogaster, Energy homeostasis and Longevity as well as Cell biology.
His Inflammation research integrates issues from Nucleoside Reverse Transcriptase Inhibitor, Senescence, Downregulation and upregulation, Retrotransposon and Interferon type I.
His study in Reverse transcriptase extends to Interferon with its themes.
His Derepression investigation overlaps with other disciplines such as Wild type, Knockout mouse and Tissue culture.
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