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Molecular Biology

D-Index
77
Citations
21879
World Ranking
1109
National Ranking
572

Overview

Vera Gorbunova is affiliated with the University of Rochester in the United States. Their research spans multiple domains within biochemistry, genetics, and molecular biology, with a particular focus on aging-related processes and molecular mechanisms.

Their work covers main fields such as Biochemistry, Genetics and Molecular Biology, and Medicine. Within these fields, subfields of study include Molecular Biology, Aging, Physiology, Genetics, and Immunology.

Vera Gorbunova has authored publications addressing a range of scientific topics, prominently including Genetics, Aging, and Longevity in Model Organisms, Epigenetics and DNA Methylation, Mitochondrial Function and Pathology, Proteoglycans and glycosaminoglycans research, Sirtuins and Resveratrol in Medicine, Telomeres, Telomerase, and Senescence, and CRISPR and Genetic Engineering.

Frequent coauthors in their work are:

  • Andrei Seluanov (94 joint publications)
  • Vadim N. Gladyshev (31 joint publications)
  • Julia Ablaeva (19 joint publications)
  • Stephan Emmrich (18 joint publications)
  • Denis Firsanov (15 joint publications)

They have published extensively in venues such as BioRxiv (Cold Spring Harbor Laboratory), Malignant Tumours, Nature Aging, Nature Communications, and Science & Technique.

Selected recent papers authored or coauthored by Vera Gorbunova include:

  • Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study (2020), The Lancet Oncology
  • The role of retrotransposable elements in ageing and age-associated diseases (2021), Nature
  • Universal DNA methylation age across mammalian tissues (2023), Nature Aging
  • DNA damage and repair in age-related inflammation (2022), Nature Reviews Immunology
  • The World Goes Bats: Living Longer and Tolerating Viruses (2020), Cell Metabolism

Best Publications

  • Ten things you should know about transposable elements

    Guillaume Bourque;Kathleen H. Burns;Mary Gehring;Vera Gorbunova

  • L1 drives IFN in senescent cells and promotes age-associated inflammation

    Marco De Cecco;Takahiro Ito;Anna P. Petrashen;Amy E. Elias

  • SIRT6 promotes DNA repair under stress by activating PARP1.

    Zhiyong Mao;Christopher Hine;Xiao Tian;Michael Van Meter

  • High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

    Xiao Tian;Jorge Azpurua;Christopher Hine;Christopher Hine;Amita Vaidya

  • Comparison of nonhomologous end joining and homologous recombination in human cells.

    Zhiyong Mao;Michael Bozzella;Andrei Seluanov;Vera Gorbunova

  • DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells.

    Zhiyong Mao;Michael Bozzella;Andrei Seluanov;Vera Gorbunova

  • Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat

    Andrei Seluanov;Christopher Hine;Jorge Azpurua;Marina Feigenson

  • Changes in DNA repair during aging.

    Vera Gorbunova;Andrei Seluanov;Zhiyong Mao;Christpher Hine

  • SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age

    Michael Van Meter;Mehr Kashyap;Sarallah Rezazadeh;Anthony J. Geneva

  • LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation

    Matthew Simon;Michael Van Meter;Julia Ablaeva;Zhonghe Ke

  • Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions

    Vera Gorbunova;Avraham A. Levy

  • Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis.

    Vera Gorbunova;Andrei Seluanov;Olivia M. Pereira-Smith

  • Establishing Primary Adult Fibroblast Cultures From Rodents

    Andrei Seluanov;Amita Vaidya;Vera Gorbunova

  • DNA end joining becomes less efficient and more error-prone during cellular senescence

    Andrei Seluanov;David Mittelman;Olivia M. Pereira-Smith;John H. Wilson

  • Mechanisms of cancer resistance in long-lived mammals.

    Andrei Seluanov;Vadim N. Gladyshev;Jan Vijg;Vera Gorbunova

  • How plants make ends meet: DNA double-strand break repair

    Vera Gorbunova;Avraham A Levy

  • The role of retrotransposable elements in ageing and age-associated diseases

    Vera Gorbunova;Andrei Seluanov;Paolo Mita;Wilson McKerrow

  • SIRT6 is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

    Xiao Tian;Denis Firsanov;Zhihui Zhang;Yang Cheng

  • ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

    Carl Koschmann;Anda-Alexandra Calinescu;Felipe J. Nunez;Alan Mackay

  • Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.

    Xiaodong Fang;Eviatar Nevo;Lijuan Han;Erez Y. Levanon

Frequent Co-Authors

Andrei Seluanov
Andrei Seluanov University of Rochester
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital
Jan Vijg
Jan Vijg Albert Einstein College of Medicine
Eviatar Nevo
Eviatar Nevo University of Haifa
Xiaodong Fang
Xiaodong Fang Beijing Genomics Institute
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
Andrei V. Gudkov
Andrei V. Gudkov Roswell Park Cancer Institute
Avraham A. Levy
Avraham A. Levy Weizmann Institute of Science
David A. Sinclair
David A. Sinclair Harvard University
Maria G. Castro
Maria G. Castro University of Michigan–Ann Arbor

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