D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 8,522 104 World Ranking 12903 National Ranking 65

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Internal medicine, Endocrinology, Biochemistry, Molecular biology and Heme oxygenase are his primary areas of study. Many of his studies involve connections with topics such as Immunology and Internal medicine. His Endocrinology research incorporates elements of Angiogenesis and Phosphorylation.

His work in the fields of Biochemistry, such as Peroxisome proliferator-activated receptor, Receptor, CD36 and Downregulation and upregulation, overlaps with other areas such as Docosahexaenoic acid. His biological study spans a wide range of topics, including Genetic transfer, Transgene and Apolipoprotein B. His Enos research includes elements of Protein kinase B and PI3K/AKT/mTOR pathway.

His most cited work include:

  • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. (876 citations)
  • Adenovirus-Mediated Heme Oxygenase-1 Gene Transfer Inhibits the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice (287 citations)
  • The Role of Interleukin 12 in the Development of Atherosclerosis in ApoE-Deficient Mice (276 citations)

What are the main themes of his work throughout his whole career to date?

Tzong-Shyuan Lee spends much of his time researching Internal medicine, Endocrinology, Cell biology, Inflammation and Pharmacology. When carried out as part of a general Endocrinology research project, his work on Cholesterol and Endothelium is frequently linked to work in Apolipoprotein E, therefore connecting diverse disciplines of study. His Cell biology study combines topics in areas such as Biochemistry and Angiogenesis.

His study focuses on the intersection of Angiogenesis and fields such as Enos with connections in the field of Protein kinase B. His Pharmacology research is multidisciplinary, incorporating elements of Oxidative stress, Bronchoalveolar lavage and Heme oxygenase. His Phosphorylation research includes themes of Nitric oxide synthase and TRPV1.

He most often published in these fields:

  • Internal medicine (34.90%)
  • Endocrinology (31.54%)
  • Cell biology (32.89%)

What were the highlights of his more recent work (between 2016-2021)?

  • Internal medicine (34.90%)
  • Endocrinology (31.54%)
  • Inflammation (21.48%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Internal medicine, Endocrinology, Inflammation, Pharmacology and Cholesterol. His work on White adipose tissue and Adipocyte as part of general Endocrinology study is frequently linked to Valsartan and Remnant kidney, therefore connecting diverse disciplines of science. His studies in Inflammation integrate themes in fields like Oxidative stress, Signal transduction, Transient receptor potential channel, Acute kidney injury and Bronchoalveolar lavage.

In his works, Tzong-Shyuan Lee performs multidisciplinary study on Pharmacology and Tube formation. His research investigates the connection between Cholesterol and topics such as ABCA1 that intersect with problems in Reverse cholesterol transport. His Enos study which covers Erythropoietin that intersects with Phosphorylation and Cell biology.

Between 2016 and 2021, his most popular works were:

  • Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Paeonol (27 citations)
  • Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol. (17 citations)
  • Role of transient receptor potential vanilloid 1 in regulating erythropoietin‐induced activation of endothelial nitric oxide synthase (16 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Tzong-Shyuan Lee focuses on Epoxide hydrolase 2, Signal transduction, Transient receptor potential channel, Pharmacology and Inflammation. His Epoxide hydrolase 2 research includes themes of Vector group, Blot, AMPK, Endothelial nitric oxide synthase and Simvastatin. His Signal transduction study combines topics from a wide range of disciplines, such as NFAT, Transgene and Pathogenesis.

His Transient receptor potential channel study frequently draws connections between adjacent fields such as Hippocampal formation. Tzong-Shyuan Lee interconnects Extracellular, Reactive oxygen species, TRPM8 and Immunology in the investigation of issues within Pharmacology. His work deals with themes such as Fibrosis, Pulmonary fibrosis, Lung and Bronchoalveolar lavage, which intersect with Inflammation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice.

Tzong-Shyuan Lee;Lee-Young Chau.
Nature Medicine (2002)

1413 Citations

Adenovirus-Mediated Heme Oxygenase-1 Gene Transfer Inhibits the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice

Shu-Hui Juan;Tzong-Shyuan Lee;Kuang-Wen Tseng;Jun-Yang Liou.
Circulation (2001)

438 Citations

The Role of Interleukin 12 in the Development of Atherosclerosis in ApoE-Deficient Mice

Tzong-Shyuan Lee;Hwei-Chen Yen;Ching-Chien Pan;Lee-Young Chau.
Arteriosclerosis, Thrombosis, and Vascular Biology (1999)

422 Citations

Expression of heme oxygenase-1 in atherosclerotic lesions.

L. J. Wang;T. S. Lee;F. Y. Lee;R. C. Pai.
American Journal of Pathology (1998)

365 Citations

Simvastatin Induces Heme Oxygenase-1 A Novel Mechanism of Vessel Protection

Tzong-Shyuan Lee;Chih-Chieh Chang;Yi Zhu;John Y.-J. Shyy.
Circulation (2004)

320 Citations

The antiinflammatory effect of laminar flow: The role of PPARγ, epoxyeicosatrienoic acids, and soluble epoxide hydrolase

Yi Liu;Yingjia Zhang;Kara Schmelzer;Tzong Shyuan Lee.
Proceedings of the National Academy of Sciences of the United States of America (2005)

313 Citations

Induction of Heme Oxygenase-1 Expression in Murine Macrophages Is Essential for the Anti-inflammatory Effect of Low Dose 15-Deoxy-Δ12,14-prostaglandin J2

Tzong-Shyuan Lee;Hui-Ling Tsai;Lee-Young Chau.
Journal of Biological Chemistry (2003)

283 Citations

Intervertebral Disc Degeneration: The Role of the Mitochondrial Pathway in Annulus Fibrosus Cell Apoptosis Induced by Overload

François Rannou;Tzong-Shyuan Lee;Rui-Hai Zhou;Jennie Chin.
American Journal of Pathology (2004)

266 Citations

Statins Activate AMP-Activated Protein Kinase In Vitro and In Vivo

Wei Sun;Tzong-Shyuan Lee;Minjia Zhu;Chunang Gu.
Circulation (2006)

260 Citations

Iron-Deficient Diet Reduces Atherosclerotic Lesions in ApoE-Deficient Mice

Tzong-Shyuan Lee;Ming-Shi Shiao;Ching-Chien Pan;Lee-Young Chau.
Circulation (1999)

228 Citations

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