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Hiroshi Kunugi

Hiroshi Kunugi

D-Index & Metrics

Medicine

D-Index
89
Citations
27269
World Ranking
12759
National Ranking
374

Overview

Hiroshi Kunugi is affiliated with Teikyo University in Japan, contributing extensively to the fields of medicine and neuroscience. Their research includes a strong focus on molecular biology, clinical psychology, cognitive neuroscience, physiology, and biological psychiatry.

The scientist's work covers a range of main topics, including:

  • Tryptophan and brain disorders
  • Stress responses and cortisol
  • Functional brain connectivity studies
  • Advanced neuroimaging techniques and applications
  • Anxiety, depression, psychometrics, treatment, cognitive processes
  • Advanced MRI techniques and applications
  • Diet and metabolism studies

Kunugi's recent papers demonstrate involvement in both psychiatric and biochemical research. Key publications include:

  • Improving polygenic prediction in ancestrally diverse populations, 2022, Nature Genetics
  • The Depression Anxiety Stress Scale 21: Development and Validation of the Depression Anxiety Stress Scale 8-Item in Psychiatric Patients and the General Public for Easier Mental Health Measurement in a Post COVID-19 World, 2021, International Journal of Environmental Research and Public Health
  • Propolis, Bee Honey, and Their Components Protect against Coronavirus Disease 2019 (COVID-19): A Review of In Silico, In Vitro, and Clinical Studies, 2021, Molecules
  • Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level, 2021, JAMA Psychiatry
  • Association between vascular endothelial growth factor-mediated blood-brain barrier dysfunction and stress-induced depression, 2022, Molecular Psychiatry

The frequent venues where Kunugi publishes include:

  • Neuropsychopharmacology Reports
  • International Journal of Environmental Research and Public Health
  • Psychiatry and Clinical Neurosciences
  • The International Journal of Neuropsychopharmacology
  • Molecular Psychiatry

Frequent collaborators in their research are:

  • Kotaro Hattori
  • Shinsuke Hidese
  • Miho Ota
  • Amira Mohammed Ali
  • Hiroaki Hori

Best Publications

  • BDNF function and intracellular signaling in neurons.

    Tadahiro Numakawa;Shingo Suzuki;Emi Kumamaru;Naoki Adachi

  • Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

    Shuichi Chiba;Tadahiro Numakawa;Midori Ninomiya;Misty C. Richards

  • Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder

    Emiko Aizawa;Hirokazu Tsuji;Takashi Asahara;Takuya Takahashi

  • Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia

    Tadahiro Numakawa;Yuki Yagasaki;Tetsuya Ishimoto;Takeya Okada

  • Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder

    H Kunugi;M Hattori;T Kato;M Tatsumi

  • Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder.

    Chihiro Kakiuchi;Kazuya Iwamoto;Mizuho Ishiwata;Miki Bundo

  • Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling

    Ryota Hashimoto;Tadahiro Numakawa;Takashi Ohnishi;Emi Kumamaru

  • A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease.

    H Kunugi;A Ueki;M Otsuka;K Isse

  • Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease.

    Miho Ota;Junko Matsuo;Ikki Ishida;Harumasa Takano

  • Association between serotonin transporter gene polymorphism and anxiety-related traits.

    Satomi Katsuragi;Hiroshi Kunugi;Akira Sano;Takashi Tsutsumi

  • Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: a Multicenter Study.

    Hiroshi Kunugi;Itsuro Ida;Toshimi Owashi;Mahito Kimura

  • Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder

    G Kirov;K C Murphy;M J Arranz;I Jones

  • Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study

    Dieter B. Wildenauer;Sibylle G. Schwab;Margot Albus;Joachim Hallmayer

  • Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression

    Hiroshi Kunugi;Hiroaki Hori;Naoki Adachi;Tadahiro Numakawa

  • Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-γ signaling for glutamate release via a glutamate transporter

    Tadahiro Numakawa;Emi Kumamaru;Naoki Adachi;Yuki Yagasaki

  • Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder

    Daimei Sasayama;Kotaro Hattori;Chisato Wakabayashi;Toshiya Teraishi

  • The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia.

    Takashi Ohnishi;Ryota Hashimoto;Takeyuki Mori;Kiyotaka Nemoto

  • Glucocorticoid Attenuates Brain-Derived Neurotrophic Factor-Dependent Upregulation of Glutamate Receptors via the Suppression of microRNA-132 Expression

    H. Kawashima;T. Numakawa;E. Kumamaru;N. Adachi

  • Brain Cannabinoid CB2 Receptor in Schizophrenia

    Hiroki Ishiguro;Yasue Horiuchi;Maya Ishikawa;Minori Koga

  • New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases

    Naoki Adachi;Tadahiro Numakawa;Misty Richards;Shingo Nakajima

Frequent Co-Authors

Hiroaki Hori
Hiroaki Hori Tokyo Medical and Dental University
Kotaro Hattori
Kotaro Hattori National Center of Neurology and Psychiatry
Shinichiro Nanko
Shinichiro Nanko Teikyo University
Ryota Hashimoto
Ryota Hashimoto National Center of Neurology and Psychiatry
Nakao Iwata
Nakao Iwata Fujita Health University
Norio Ozaki
Norio Ozaki Nagoya University
Tadafumi Kato
Tadafumi Kato Juntendo University
Noriko Sato
Noriko Sato Tokyo Medical and Dental University
Takeo Yoshikawa
Takeo Yoshikawa RIKEN Center for Brain Science
Tadao Arinami
Tadao Arinami University of Tsukuba

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