World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
79
Citations
19820
World Ranking
1649
National Ranking
60

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Mutation

Takeo Yoshikawa mainly focuses on Genetics, Single-nucleotide polymorphism, Schizophrenia, Bipolar disorder and Psychosis. Haplotype, Genetic association, Allele frequency, Linkage disequilibrium and Gene are subfields of Genetics in which his conducts study. Takeo Yoshikawa has researched Single-nucleotide polymorphism in several fields, including Proband, Allele and Candidate gene.

His biological study deals with issues like Microsatellite, which deal with fields such as Craniofacial, Chromosome and SNP. Takeo Yoshikawa interconnects Genotyping, Genetic linkage and Genome Scan in the investigation of issues within Bipolar disorder. The concepts of his Psychosis study are interwoven with issues in Endocrinology, Mutation, Pentosidine, Alternative splicing and Internal medicine.

His most cited work include:

  • Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease (1026 citations)
  • Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (536 citations)
  • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2 (383 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Genetics, Schizophrenia, Single-nucleotide polymorphism, Internal medicine and Endocrinology. Many of his studies on Genetics involve topics that are commonly interrelated, such as Bipolar disorder. Takeo Yoshikawa combines subjects such as Quantitative trait locus, Psychosis, Prefrontal cortex and Autism spectrum disorder with his study of Schizophrenia.

The Single-nucleotide polymorphism study combines topics in areas such as Allele frequency and Candidate gene. His work carried out in the field of Internal medicine brings together such families of science as Corpus callosum and Oncology. The various areas that Takeo Yoshikawa examines in his Endocrinology study include Cholecystokinin, Receptor, Methamphetamine and Polyunsaturated fatty acid.

He most often published in these fields:

  • Genetics (63.48%)
  • Schizophrenia (28.01%)
  • Single-nucleotide polymorphism (27.66%)

What were the highlights of his more recent work (between 2015-2021)?

  • Genetics (63.48%)
  • Internal medicine (22.70%)
  • Schizophrenia (28.01%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Genetics, Internal medicine, Schizophrenia, Endocrinology and Gene. His work on Genetics deals in particular with Candidate gene, Missense mutation, Allele, FABP7 and Penetrance. His studies deal with areas such as Genome-wide association study, Genetic variation and Copy-number variation as well as Candidate gene.

His Internal medicine study combines topics in areas such as Docosahexaenoic acid, IDH2, IDH1, Pathology and IDH3G. His Schizophrenia research is multidisciplinary, incorporating perspectives in Young adult, Psychosis, Case-control study, Genetic association and Autism spectrum disorder. His Endocrinology research is multidisciplinary, incorporating elements of Offspring, Corpus callosum and Polyunsaturated fatty acid.

Between 2015 and 2021, his most popular works were:

  • A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder (90 citations)
  • Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder. (68 citations)
  • Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis. (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Mutation

Takeo Yoshikawa mainly investigates Genetics, Neuroscience, Gene, Autism spectrum disorder and Autism. Genome-wide association study and Genetic association are among the areas of Genetics where Takeo Yoshikawa concentrates his study. His research in Genome-wide association study intersects with topics in Polymorphism and Candidate gene.

His study in Candidate gene is interdisciplinary in nature, drawing from both Neurodevelopmental disorder, SNP array, Single-nucleotide polymorphism, Comparative genomic hybridization and Genetic variation. His research investigates the connection between Genetic association and topics such as In silico that intersect with problems in Schizophrenia. His biological study spans a wide range of topics, including Synaptic plasticity and Induced pluripotent stem cell.

Best Publications

  • Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

    Wataru Satake;Yuko Nakabayashi;Yuko Nakabayashi;Ikuko Mizuta;Ikuko Mizuta;Yushi Hirota;Yushi Hirota

  • Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.

    Ricardo Segurado;Sevilla D. Detera-Wadleigh;Douglas F. Levinson;Cathryn M. Lewis

  • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2

    Sevilla D. Detera-Wadleigh;Judith A. Badner;Judith A. Badner;Wade H. Berrettini;Takeo Yoshikawa

  • 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

    Ryuichi Harada;Nobuyuki Okamura;Shozo Furumoto;Katsutoshi Furukawa

  • Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia

    Miki Bundo;Manabu Toyoshima;Yohei Okada;Wado Akamatsu

  • Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease.

    Nobuyuki Okamura;Shozo Furumoto;Ryuichi Harada;Tetsuro Tago

  • DNA Methylation Status of SOX10 Correlates with Its Downregulation and Oligodendrocyte Dysfunction in Schizophrenia

    Kazuya Iwamoto;Miki Bundo;Kazuo Yamada;Hitomi Takao

  • Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients.

    Tetsushi Sadakata;Miwa Washida;Yoshimi Iwayama;Satoshi Shoji

  • Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights

    Itaru Kushima;Branko Aleksic;Masahiro Nakatochi;Teppei Shimamura

  • Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype

    Akiko Watanabe;Tomoko Toyota;Yuji Owada;Takeshi Hayashi

  • A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder

    M Ikeda;A Takahashi;Y Kamatani;Y Okahisa

  • Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.

    Toshio Munesue;Shigeru Yokoyama;Kazuhiko Nakamura;Ayyappan Anitha

  • Enhanced Carbonyl Stress in a Subpopulation of Schizophrenia

    Makoto Arai;Hiroko Yuzawa;Izumi Nohara;Tetsuo Ohnishi

  • Low serum levels of brain-derived neurotrophic factor and epidermal growth factor in patients with chronic schizophrenia.

    Yumiko Ikeda;Noriaki Yahata;Itsuo Ito;Masatoshi Nagano

  • Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia.

    Kazuo Yamada;David J. Gerber;Yoshimi Iwayama;Tetsuo Ohnishi

  • Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels.

    Kazuo Yamada;Tetsuo Ohnishi;Kenji Hashimoto;Hisako Ohba

  • The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment.

    Thomas G. Schulze;Martin Alda;Mazda Adli;Nirmala Akula

  • Genome-wide profiling of promoter methylation in human

    Izuho Hatada;Masayuki Fukasawa;Mika Kimura;Sumiyo Morita

  • Association between polymorphisms in the promoter region of the sialyltransferase 8B (SIAT8B) gene and schizophrenia.

    Makoto Arai;Kazuo Yamada;Tomoko Toyota;Nanako Obata

  • Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder.

    Atsushi Takata;Noriko Miyake;Yoshinori Tsurusaki;Ryoko Fukai

Frequent Co-Authors

Kazuo Yamada
Kazuo Yamada RIKEN Center for Brain Science
Tadafumi Kato
Tadafumi Kato Juntendo University
Sevilla D. Detera-Wadleigh
Sevilla D. Detera-Wadleigh National Institutes of Health
Norio Ozaki
Norio Ozaki Nagoya University
Nakao Iwata
Nakao Iwata Fujita Health University
Hiroshi Kunugi
Hiroshi Kunugi Teikyo University
Yoshio Minabe
Yoshio Minabe Kanazawa University
Mitsuru Kikuchi
Mitsuru Kikuchi Kanazawa University
Kazuya Iwamoto
Kazuya Iwamoto Kumamoto University
Hideo Matsuzaki
Hideo Matsuzaki University of Fukui

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