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D-Index & Metrics

Medicine

D-Index
86
Citations
30769
World Ranking
14009
National Ranking
581

Research.com Recognitions

  • 2014 - Fellow of the Royal Society of Canada Academy of Science

Overview

Duncan J. Stewart is affiliated with the Ottawa Hospital Research Institute in Canada. Their research spans multiple areas within medicine and biomedical sciences, with a particular focus on pulmonary and respiratory medicine, molecular biology, genetics, cardiology and cardiovascular medicine, and surgery.

The main fields of study covered in their body of work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their research delves into several subfields such as:

  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Genetics
  • Cardiology and Cardiovascular Medicine
  • Surgery

The primary topics of their research address various biomedical challenges, including:

  • Pulmonary Hypertension Research and Treatments
  • Mesenchymal stem cell research
  • Extracellular vesicles in disease
  • Neonatal Respiratory Health Research
  • MicroRNA in disease regulation
  • Respiratory Support and Mechanisms
  • Congenital Heart Disease Studies

Duncan J. Stewart has contributed to several high-impact publications across different venues. Some of the recent papers include:

  • Endothelial cells in the pathogenesis of pulmonary arterial hypertension, 2021, European Respiratory Journal
  • Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis, 2020, EClinicalMedicine
  • An Analysis of Mesenchymal Stem Cell-Derived Extracellular Vesicles for Preclinical Use, 2020, ACS Nano
  • Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice, 2020, Nature Neuroscience
  • Mesenchymal stromal cell extracellular vesicles as therapy for acute and chronic respiratory diseases: A meta-analysis, 2021, Journal of Extracellular Vesicles

The scientist frequently publishes in venues such as:

  • Cytotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation
  • European Respiratory Journal
  • American Journal of Respiratory and Critical Care Medicine

Frequent collaborators in their research include:

  • Yupu Deng
  • Shirley H. J. Mei
  • David W. Courtman
  • Nicholas D Cober
  • Dean Fergusson

Duncan J. Stewart was recognized as a Fellow of the Royal Society of Canada in 2014 by the Academy of Science.

Best Publications

  • Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

    Adel Giaid;Masashi Yanagisawa;David Langleben;René P. Michel

  • A Self-Fulfilling Prophecy C-Reactive Protein Attenuates Nitric Oxide Production and Inhibits Angiogenesis

    Subodh Verma;Chao-Hung Wang;Shu-Hong Li;Aaron S. Dumont

  • Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials

    Manoj M. Lalu;Lauralyn McIntyre;Lauralyn McIntyre;Christina Pugliese;Dean Fergusson

  • Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis

    Shirley H. J. Mei;Jack J. Haitsma;Claudia C. Dos Santos;Yupu Deng

  • C-Reactive Protein Attenuates Endothelial Progenitor Cell Survival, Differentiation, and Function Further Evidence of a Mechanistic Link Between C-Reactive Protein and Cardiovascular Disease

    Subodh Verma;Michael A. Kuliszewski;Shu Hong Li;Paul E. Szmitko

  • Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial.

    Jean L Rouleau;Marc A Pfeffer;Duncan J Stewart;Debra Isaac

  • Immunoreactive endothelin in human plasma: marked elevations in patients in cardiogenic shock.

    Peter Cernacek;Duncan J. Stewart

  • Bone Morphogenetic Protein Receptor-2 Signaling Promotes Pulmonary Arterial Endothelial Cell Survival: Implications for Loss-of-Function Mutations in the Pathogenesis of Pulmonary Hypertension

    Krystyna Teichert-Kuliszewska;Michael J.B. Kutryk;Michael A. Kuliszewski;Golnaz Karoubi

  • Increased plasma endothelin-1 in the early hours of acute myocardial infarction.

    Duncan J. Stewart;George Kubac;Kevin B. Costello;Peter Cernacek

  • Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation.

    Georg Hansmann;Roger A. Wagner;Stefan Schellong;Vinicio A. de Jesus Perez

  • Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2.

    Krystyna Teichert-Kuliszewska;Peter C. Maisonpierre;Nina Jones;Andrew I.M. Campbell

  • Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death.

    Imran N. Mungrue;Robert Gros;Xiaomang You;Asif Pirani

  • Endothelial Progenitor Cells New Hope for a Broken Heart

    Paul E. Szmitko;Paul W.M. Fedak;Richard D. Weisel;Duncan J. Stewart

  • Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment.

    D J Stewart;J D Hilton;J M O Arnold;J Gregoire

  • Myocardial infarction patients in the 1990s—their risk factors, stratification and survival in Canada: The Canadian assessment of myocardial infarction (CAMI) study

    Jean L. Rouleau;Mario Talajic;Bruce Sussex;Louise Potvin

  • Elevated endothelin-1 in heart failure and loss of normal response to postural change.

    D J Stewart;P Cernacek;K B Costello;J L Rouleau

  • VEGF gene therapy fails to improve perfusion of ischemic myocardium in patients with advanced coronary disease: results of the NORTHERN trial.

    Duncan J Stewart;Michael Jb Kutryk;David Fitchett;Michael Freeman

  • Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.

    Fina Lovren;Yi Pan;Adrian Quan;Hwee Teoh

  • Short-term Pulmonary Vasodilation With l-Arginine in Pulmonary Hypertension

    Sanjay Mehta;Duncan J. Stewart;David Langleben;Robert D. Levy

  • Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2.

    Paola Caruso;Benjamin John Dunmore;Kenny Schlosser;Sandra Schoors

Frequent Co-Authors

Michael R. Freeman
Michael R. Freeman Cedars-Sinai Medical Center
Geoffrey Burnstock
Geoffrey Burnstock University College London
Thomas Münzel
Thomas Münzel Johannes Gutenberg University of Mainz
Michael J. Mulvany
Michael J. Mulvany Aarhus University
William M. Chilian
William M. Chilian Northeast Ohio Medical University
Masashi Yanagisawa
Masashi Yanagisawa University of Tsukuba
Tomoh Masaki
Tomoh Masaki Kyoto University
Jean-Claude Stoclet
Jean-Claude Stoclet Centre national de la recherche scientifique, CNRS
Sadao Kimura
Sadao Kimura Chiba University
Pierre Savard
Pierre Savard University of Toronto

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