Sadao Kimura

Overview

Best Publications

• A novel potent vasoconstrictor peptide produced by vascular endothelial cells.

  Masashi Yanagisawa;Hiroki Kurihara;Hiroki Kurihara;Sadao Kimura;Yoko Tomobe

  14865
  Citations

• The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

  Akihiro Inoue;Masashi Yanagisawa;Sadao Kimura;Yoshitoshi Kasuya

  3558
  Citations

• Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.

  Takeshi Sakurai;Masashi Yanagisawa;Yoh Takuwa;Hitoshi Miyazaki

  3073
  Citations

• Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

  Adel Giaid;Masashi Yanagisawa;David Langleben;René P. Michel

  2378
  Citations

• Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide.

  M Yanagisawa;A Inoue;T Ishikawa;Y Kasuya

  725
  Citations

• Molecular and cellular mechanism of endothelin regulation. Implications for vascular function.

  Tomoh Masaki;Sadao Kimura;Masashi Yanagisawa;Katsutoshi Goto

  561
  Citations

• Novel Neuropeptides, Neurokinin α and β, Isolated from Porcine Spinal Cord

  Sadao Kimura;Masahiro Okada;Yoshiki Sugita;Ichiro Kanazawa

  510
  Citations

• Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.

  Katsutoshi Goto;Yoshitoshi Kasuya;Norio Matsuki;Yoh Takuwa

  480
  Citations

• A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels.

  Masashi Yanagisawa;Hiroki Kurihara;Sadao Kimura;Katsutoshi Goto

  400
  Citations

• Endothelin: A novel peptide in the posterior pituitary system

  Toshihiro Yoshizawa;Osamu Shinmi;Adel Giaid;Masashi Yanagisawa

  378
  Citations

• Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum.

  Alvin S. Stern;Randolph V. Lewis;Sadao Kimura;Jean Rossier

  352
  Citations

• An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin.

  Randolph V. Lewis;Alvin S. Stern;Sadao Kimura;Jean Rossier

  328
  Citations

• cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA

  Takeshi Sakurai;Masashi Yanagisawa;Akihiro Inoue;Una S. Ryan

  326
  Citations

• The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

  Koichi Gonda;Hiroyuki Okamoto;Noriko Takuwa;Yutaka Yatomi

  311
  Citations

• Regional distribution of substance P, neurokinin α and neurokinin β in rat spinal cord, nerve roots and dorsal root ganglia, and the effects of dorsal root section or spinal transection

  Tatsuji Ogawa;Tatsuji Ogawa;Ichiro Kanazawa;Sadao Kimura

  310
  Citations

• RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

  Min Jae Lee;Takafumi Tasaki;Kayoko Moroi;Jee Young An

  291
  Citations

• Effects of endothelin on the renal artery from spontaneously hypertensive and Wistar Kyoto rats.

  Yoko Tomobe;Takashi Miyauchi;Akira Saito;Masashi Yanagisawa

  290
  Citations

• Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide.

  Tomohisa Ishikawa;Masashi Yanagisawa;Sadao Kimura;Katsutoshi Goto

  286
  Citations

• Structure-activity relationships of endothelin: importance of the C-terminal moiety.

  Sadao Kimura;Yoshitoshi Kasuya;Tatsuya Sawamura;Osamu Shinmi

  258
  Citations

• Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: structure-activity relationships of big endothelin-1.

  Sadao Kimura;Yoshitoshi Kasuya;Tatsuya Sawamura;Osamu Shinmi

  244
  Citations