World's Best Scientists 2026 revealed!
Hitoshi Hashimoto

Hitoshi Hashimoto

D-Index & Metrics

Neuroscience

D-Index
62
Citations
13591
World Ranking
3531
National Ranking
99

Overview

Hitoshi Hashimoto is affiliated with Osaka University in Japan and has a substantial body of research primarily in the fields of neuroscience and biochemistry, genetics, and molecular biology. Their work spans several subfields including cellular and molecular neuroscience, molecular biology, cognitive neuroscience, social psychology, and behavioral neuroscience.

The scientist's research topics encompass various aspects of neuropeptides and animal physiology, neuroendocrine regulation and behavior, receptor mechanisms and signaling, stress responses and cortisol, neuroscience and neuropharmacology research, tryptophan and brain disorders, and memory and neural mechanisms.

Key recent publications include:

  • "Molecular basis of astrocyte diversity and morphology across the CNS in health and disease" (2022), published in Science
  • "Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes" (2020), published in Nature Communications
  • "Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses" (2022), published in Science Advances
  • "(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression" (2020), published in Pharmacology Biochemistry and Behavior
  • "Exploring rare cellular activity in more than one million cells by a transscale scope" (2021), published in Scientific Reports

Frequent co-authors collaborating on these research efforts include Atsushi Kasai, Yukio Ago, Takanobu Nakazawa, Kaoru Seiriki, and Atsuko Hayata-Takano.

The scientist often publishes in venues such as the Proceedings for Annual Meeting of The Japanese Pharmacological Society, bioRxiv (Cold Spring Harbor Laboratory), Molecular Brain, Journal of Pharmacological Sciences, and The International Journal of Neuropsychopharmacology.

Best Publications

  • Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

    David Vaudry;Anthony Falluel-Morel;Steve Bourgault;Magali Basille

  • Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP)

    Hitoshi Hashimoto;Norihito Shintani;Kazuhiro Tanaka;Wakaba Mori

  • Apelin is a novel angiogenic factor in retinal endothelial cells

    Atsushi Kasai;Norihito Shintani;Maki Oda;Michiya Kakuda

  • Molecular cloning and tissue distribution of a receptor for pituitary adenylate cyclase-activating polypeptide

    Hitoshi Hashimoto;Hitoshi Hashimoto;Takeshi Ishihara;Ryuichi Shigemoto;Kensaku Mori

  • Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: An in situ hybridization study

    Hitoshi Hashimoto;Hiroyuki Nogi;Kensaku Mori;Hitoshi Ohishi

  • Pituitary adenylate cyclase-activating polypeptide (PACAP) decreases ischemic neuronal cell death in association with IL-6.

    Hirokazu Ohtaki;Tomoya Nakamachi;Tomoya Nakamachi;Kenji Dohi;Yoichi Aizawa

  • Postsynaptic 5-hydroxytryptamine1A receptor activation increases in vivo dopamine release in rat prefrontal cortex

    M Sakaue;P Somboonthum;B Nishihara;Y Koyama

  • Pituitary adenylate cyclase-activating polypeptide plays a key role in nitroglycerol-induced trigeminovascular activation in mice

    Adrienn Markovics;Viktoria Kormos;Balazs Gaszner;Arvin Lashgarara

  • Expression of glutamate transporters in cultured glial cells.

    Kaoru Kondo;Hitoshi Hashimoto;Jun-ichi Kitanaka;Makoto Sawada

  • Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia.

    R Hashimoto;H Hashimoto;N Shintani;S Chiba

  • Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

    D. Watanabe;T. Suda;H. Hashimoto;S. Nagata

  • Retardation of Retinal Vascular Development in Apelin-Deficient Mice

    Atsushi Kasai;Norihito Shintani;Hideaki Kato;Satoshi Matsuda

  • Pituitary Adenylate Cyclase-Activating Polypeptide Is Required for the Development of Spinal Sensitization and Induction of Neuropathic Pain

    Tamaki Mabuchi;Norihito Shintani;Shinji Matsumura;Emiko Okuda-Ashitaka

  • Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

    Kazuhiro Takuma;Yuta Hara;Shunsuke Kataoka;Takuya Kawanai

  • The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleus, ventral lateral septum, and dorsal raphe nucleus.

    B. Gaszner;V. Kormos;T. Kozicz;H. Hashimoto;H. Hashimoto

  • PACAP is an Endogenous Protective Factor—Insights from PACAP-Deficient Mice

    D. Reglodi;P. Kiss;K. Szabadfi;T. Atlasz

  • Cultured rat astrocytes possess Na+-Ca2+ exchanger

    Kazuhiro Takuma;Toshio Matsuda;Hitoshi Hashimoto;Shoichi Asano

  • High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates

    Kaoru Seiriki;Atsushi Kasai;Takeshi Hashimoto;Wiebke Schulze

  • Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala.

    Ryota Haba;Ryota Haba;Norihito Shintani;Yusuke Onaka;Hyper Wang

  • KB-R7943 Inhibits Store-Operated Ca2+ Entry in Cultured Neurons and Astrocytes

    Naohisa Arakawa;Masaki Sakaue;Ikuko Yokoyama;Hitoshi Hashimoto

Frequent Co-Authors

Kazuhiro Takuma
Kazuhiro Takuma Osaka University
Takanobu Nakazawa
Takanobu Nakazawa Osaka University
Ryota Hashimoto
Ryota Hashimoto National Center of Neurology and Psychiatry
Andrea Tamas
Andrea Tamas University of Pecs
Peter Kiss
Peter Kiss University of Pecs
James A. Waschek
James A. Waschek University of California, Los Angeles
Masatoshi Takeda
Masatoshi Takeda Izumi University
Katsuya Nagai
Katsuya Nagai Osaka University
Taiichi Katayama
Taiichi Katayama Osaka University
Satoshi Kawata
Satoshi Kawata Osaka University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring neuroscience opens doors to a wide range of online degrees and career pathways, especially for those interested in the brain, behavior, and mental health. Beyond neuroscience, students often consider related fields that can lead to rewarding roles in counseling, therapy, social work, and psychology.

For those looking into counseling careers, a masters in marriage and family therapy online is a popular choice, preparing graduates for licensure and therapeutic practice. If you are aiming to become a psychologist or pursue advanced research, an affordable online master's in psychology offers practical coursework with flexibility in learning.

Undergraduate students may start with a cheap online psychology degree to gain foundational knowledge, or those interested in rapid entry into the workforce can consider a 1 year online master's in social work, which can fast-track a career in community or clinical social work. Online options in these fields make it easier than ever to gain specialized skills while offering the flexibility many students need.

Best Scientists Citing Hitoshi Hashimoto

Trending Scientists

Recently Published Articles