Kazuhiro Takuma

Overview

Best Publications

• ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

  Joyce W. Lustbader;Maurizio Cirilli;Chang Lin;Hong Wei Xu;Hong Wei Xu

  1620
  Citations

• Astrocyte apoptosis: implications for neuroprotection.

  Kazuhiro Takuma;Akemichi Baba;Toshio Matsuda

  631
  Citations

• SEA0400, a Novel and Selective Inhibitor of the Na+-Ca2+ Exchanger, Attenuates Reperfusion Injury in the in Vitro and in Vivo Cerebral Ischemic Models

  Toshio Matsuda;Naohisa Arakawa;Kazuhiro Takuma;Yoko Kishida

  520
  Citations

• Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid.

  Shunsuke Kataoka;Kazuhiro Takuma;Yuta Hara;Yuko Maeda

  362
  Citations

• RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction

  Kazuhiro Takuma;Fang Fang;Wensheng Zhang;Wensheng Zhang;Shiqiang Yan;Shiqiang Yan

  355
  Citations

• ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction

  Kazuhiro Takuma;Jun Yao;Jianmin Huang;Hongwei Xu

  343
  Citations

• Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice.

  Ken Koda;Yukio Ago;Yana Cong;Yuki Kita

  305
  Citations

• Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice

  Daisuke Ibi;Kazuhiro Takuma;Hiroyuki Koike;Hiroyuki Mizoguchi

  265
  Citations

• Behavioral abnormality and pharmacologic response in social isolation-reared mice

  Hiroyuki Koike;Daisuke Ibi;Hiroyuki Mizoguchi;Taku Nagai

  257
  Citations

• Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice.

  Hiroyuki Kamei;Taku Nagai;Taku Nagai;Hiroko Nakano;Yuriko Togan

  228
  Citations

• Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore.

  Kazuhiro Takuma;Patamawan Phuagphong;Eibai Lee;Koichi Mori

  220
  Citations

• Matrix metalloproteinase-9 contributes to kindled seizure development in pentylenetetrazole-treated mice by converting pro-BDNF to mature BDNF in the hippocampus

  Hiroyuki Mizoguchi;Junya Nakade;Masaki Tachibana;Daisuke Ibi;Daisuke Ibi

  210
  Citations

• Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex.

  Taku Nagai;Kazuhiro Takuma;Hiroyuki Kamei;Yukio Ito

  203
  Citations

• Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease.

  Kazuhiro Takuma;Shirley ShiDu Yan;David M. Stern;Kiyofumi Yamada

  190
  Citations

• Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood

  Daisuke Ibi;Taku Nagai;Yuko Kitahara;Hiroyuki Mizoguchi

  153
  Citations

• Pharmacological Aspects of the Acetylcholinesterase Inhibitor Galantamine

  Yukio Ago;Ken Koda;Kazuhiro Takuma;Toshio Matsuda;Toshio Matsuda

  148
  Citations

• Na(+)-Ca2+ exchanger: physiology and pharmacology.

  Toshio Matsuda;Kazuhiro Takuma;Kazuhiro Takuma;Akemichi Baba

  143
  Citations

• Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

  Kazuhiro Takuma;Yuta Hara;Shunsuke Kataoka;Takuya Kawanai

  137
  Citations

• Cultured rat astrocytes possess Na+-Ca2+ exchanger

  Kazuhiro Takuma;Toshio Matsuda;Hitoshi Hashimoto;Shoichi Asano

  134
  Citations

• High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates

  Kaoru Seiriki;Atsushi Kasai;Takeshi Hashimoto;Wiebke Schulze

  131
  Citations