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Neuroscience

D-Index
47
Citations
9240
World Ranking
6400
National Ranking
37

Overview

Choon-Gon Jang is affiliated with Sungkyunkwan University in South Korea and has contributed extensively to the fields of medicine, pharmacology, toxicology, and neuroscience. Their research output includes 51 publications in medicine, with significant focus on pharmacology, toxicology, and pharmaceutics, represented by 34 publications in this combined field and 30 specifically in neuroscience.

Their recent publications reflect a focus on pharmacogenetics and drug metabolism, as well as neuropharmacology. Notable papers include:

  • Flavonoids as therapeutic candidates for emotional disorders such as anxiety and depression (2020, Archives of Pharmacal Research)
  • Physiologically based pharmacokinetic (PBPK) modeling for prediction of celecoxib pharmacokinetics according to CYP2C9 genetic polymorphism (2021, Archives of Pharmacal Research)
  • Effects of CYP2D6 genetic polymorphism on the pharmacokinetics of metoclopramide (2020, Archives of Pharmacal Research)
  • ABCB1 c.2677G>T/c.3435C>T diplotype increases the early-phase oral absorption of losartan (2020, Archives of Pharmacal Research)
  • Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson's disease (2021, Archives of Pharmacal Research)

Jang's research addresses multiple main topics, including:

  • Pharmacogenetics and Drug Metabolism
  • Neurotransmitter Receptor Influence on Behavior
  • Drug Transport and Resistance Mechanisms
  • Analytical Methods in Pharmaceuticals
  • Forensic Toxicology and Drug Analysis
  • Inflammatory mediators and NSAID effects
  • Antibiotics Pharmacokinetics and Efficacy

The scientist frequently publishes in the following academic venues:

  • Archives of Pharmacal Research (26 publications)
  • Archives of Toxicology (3 publications)
  • Biomolecules & Therapeutics (3 publications)
  • British Journal of Pharmacology (3 publications)
  • Food and Chemical Toxicology (2 publications)

Collaborations have been sustained with several frequent co-authors, including:

  • Seok-Yong Lee (41 co-authored publications)
  • Yun Jeong Lee (23 co-authored publications)
  • Pureum Kang (22 co-authored publications)
  • Chang-Keun Cho (22 co-authored publications)
  • Jung-Woo Bae (18 co-authored publications)

The subfields contributing to their research include pharmacology with 46 publications, cellular and molecular neuroscience with 18, oncology with 11, analytical chemistry with 8, and toxicology with 7. These areas demonstrate an interdisciplinary approach combining molecular study with clinical and toxicological applications.

Best Publications

  • Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice

    Seung-Hwan Kwon;Ha-Kyung Lee;Ji-Ah Kim;Sa-Ik Hong

  • Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.

    Seung Hyun Baek;So Jung Park;Jae In Jeong;Sung Hyun Kim

  • Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice

    Yu-Hua Tian;Joung-Hee Baek;Seok-Yong Lee;Choon-Gon Jang

  • Ginsenoside Re Rescues Methamphetamine-Induced Oxidative Damage, Mitochondrial Dysfunction, Microglial Activation, and Dopaminergic Degeneration by Inhibiting the Protein Kinase Cδ Gene

    Eun Joo Shin;Seung Woo Shin;Thuy Ty Lan Nguyen;Dae Hun Park;Dae Hun Park

  • Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells.

    Seung-Hwan Kwon;Ji-Ah Kim;Sa-Ik Hong;Yang-Hee Jung

  • Loganin improves learning and memory impairments induced by scopolamine in mice.

    Seung-Hwan Kwon;Hyoung-Chun Kim;Seok-Yong Lee;Choon-Gon Jang

  • Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors

    Eun-Joo Shin;Duy-Khanh Dang;The-Vinh Tran;Hai-Quyen Tran

  • Allele and genotype frequencies of CYP2C9 in a Korean population.

    Jung-Woo Bae;Hyun-Kyung Kim;Ji-Hong Kim;Sang-In Yang

  • Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

    Duy Khanh Dang;Eun Joo Shin;Yunsung Nam;Sungwoo Ryoo

  • Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Attenuates Alzheimer's Disease-Related Neuropathies: Involvement of Non-Amyloidogenic Processing

    Sung Hee Hwang;Eun-Joo Shin;Tae-Joon Shin;Byung-Hwan Lee

  • Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice

    Hack-Seang Kim;Woo-Kyu Park;Choon-Gon Jang;Seikwan Oh

  • Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice.

    Hyun-Sook Yu;Seok-Yong Lee;Choon-Gon Jang

  • A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats

    Choon-Gon Jang;Timothy Whitfield;Gery Schulteis;George F. Koob

  • Role of Mitochondria in Methamphetamine-Induced Dopaminergic Neurotoxicity: Involvement in Oxidative Stress, Neuroinflammation, and Pro-apoptosis-A Review.

    Eun Joo Shin;Hai Quyen Tran;Phuong Tram Nguyen;Ji Hoon Jeong

  • Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta25–35-induced learning and memory impairments in mice

    Seung-Hwan Kwon;Ha-Kyung Lee;Ji-Ah Kim;Sa-Ik Hong

  • Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT1A, GABAA, and NMDA receptors

    In-Jee You;Yang-Hee Jung;Min-Jung Kim;Seung-Hwan Kwon

  • The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells

    Seung-Hwan Kwon;Sa-Ik Hong;Ji-Ah Kim;Yang-Hee Jung

  • Inhibition by MK-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice

    Hack-Seang Kim;Choon-Gon Jang;Woo-Kyu Park

  • Antidepressant-like effects of Albizzia julibrissin in mice: involvement of the 5-HT1A receptor system.

    Ji-Hyun Kim;Sun Yeou Kim;Seok-Yong Lee;Choon-Gon Jang

  • Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

    Seok Joo Park;Eun Joo Shin;Sun Seek Min;Jihua An

  • Region specific expression of NMDA receptor NR1 subunit mRNA in hypothalamus and pons following chronic morphine treatment

    Hong Zhu;Choon-Gon Jang;Tangeng Ma;Seikwan Oh

  • Liposomal melatonin rescues methamphetamine-elicited mitochondrial burdens, pro-apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene.

    Xuan Khanh Thi Nguyen;Jaehwi Lee;Eun Joo Shin;Duy Khanh Dang

Frequent Co-Authors

Eun-Joo Shin
Eun-Joo Shin Kangwon National University
Guoying Bing
Guoying Bing University of Kentucky
Sang-Ho Choi
Sang-Ho Choi Seoul National University
Young Hee Lee
Young Hee Lee Sungkyunkwan University
Won Ki Kim
Won Ki Kim Korea University
Insop Shim
Insop Shim Kyung Hee University
Ole Petter Ottersen
Ole Petter Ottersen University of Oslo

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