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Biology and Biochemistry

D-Index
88
Citations
25229
World Ranking
2728
National Ranking
1412

Overview

Horace H. Loh is affiliated with the University of Minnesota in the United States. Their research intersects multiple fields including Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine, contributing to a diverse range of scientific inquiries.

Their work encompasses several subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Psychiatry and Mental Health, Developmental Neuroscience, and Cognitive Neuroscience. The main topics covered in their research include Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Pharmacological Receptor Mechanisms and Effects, Epilepsy Research and Treatment, Neurogenesis and Neuroplasticity Mechanisms, and Pain Mechanisms and Treatments.

Their recent publications reflect this breadth of interest and research focus:

  • Automatic detection of interictal ripples on scalp EEG to evaluate the effect and prognosis of ACTH therapy in patients with infantile spasms, 2021, Epilepsia
  • Kappa opioid receptor controls neural stem cell differentiation via a miR-7a/Pax6 dependent pathway, 2021, Stem Cells
  • Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway, 2020, Cell Reports
  • Proteins in DNA methylation and their role in neural stem cell proliferation and differentiation, 2021, Cell Regeneration
  • Localization of the Epileptogenic Zone by Multimodal Neuroimaging and High-Frequency Oscillation, 2021, Frontiers in Human Neuroscience

Frequent publication venues for this researcher include:

  • The FASEB Journal
  • European Journal of Medicinal Chemistry
  • Epilepsia
  • Stem Cells
  • Cell Reports

Horace H. Loh has collaborated regularly with a number of co-authors, including:

  • Ping-Yee Law
  • Yue Xing
  • Xiaofeng Yang
  • Shiu-Hwa Yeh
  • Hui Zheng

The research contributions from Loh cover critical aspects of neuroscience and molecular biology, particularly focusing on how neural stem cells proliferate and differentiate, the role of receptor mechanisms in these processes, and the broader implications for disorders such as epilepsy and pain management.

Best Publications

  • Molecular Mechanisms and Regulation of Opioid Receptor Signaling

    Ping Yee Law;Yung H. Wong;Horace H Loh

  • Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord

    Ulf Arvidsson;Maureen Riedl;Sumita Chakrabarti;Jang Hern Lee

  • Effects of opioids on the immune system

    Sabita Roy;Horace H. Loh

  • The role of membrane lipids in receptor mechanisms.

    H H Loh;P Y Law

  • Immunofluorescent identification of a delta (delta)-opioid receptor on primary afferent nerve terminals.

    Robert J. Dado;P. Y. Law;Horace H Loh;Robert Elde

  • β-Arrestin-Dependent μ-Opioid Receptor-Activated Extracellular Signal-Regulated Kinases (ERKs) Translocate to Nucleus in Contrast to G Protein-Dependent ERK Activation

    Hui Zheng;Horace H. Loh;Ping-Yee Law

  • Demonstration and Characterization of Opiate Inhibition of the Striatal Adenylate Cyclase

    P. Y. Law;J. Wu;J. E. Koehler;H. H. Loh

  • The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids

    U Arvidsson;M Riedl;S Chakrabarti;L Vulchanova

  • MU-opioid receptor-knockout mice: role of μ-opioid receptor in morphine mediated immune functions

    Sabita Roy;Roderick A Barke;Horace H Loh

  • Spinal G-Protein-Gated Potassium Channels Contribute in a Dose-Dependent Manner to the Analgesic Effect of μ- and δ- But Not κ-Opioids

    Cheryl L. Marker;Rafael Luján;Horace H Loh;Kevin D Wickman

  • Phosphorylation of Ser363, Thr370, and Ser375 Residues within the Carboxyl Tail Differentially Regulates μ-Opioid Receptor Internalization *

    Rachid El Kouhen;Amy L. Burd;Laurie J. Erickson-Herbrandson;Chia Yu Chang

  • Rewarding effects of ethanol and cocaine in µ opioid receptor-deficient mice

    Axel Becker;Gisela Grecksch;Jürgen Kraus;Horace H. Loh

  • Poly(C)-binding proteins as transcriptional regulators of gene expression

    Hack Sun Choi;Cheol Kyu T Hwang;Kyu Young Song;Ping-Yee Law

  • Heterodimerization of μ- and δ-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions

    Ping Yee Law;Laurie J. Erickson-Herbrandson;Qin Q. Zha;Jon Solberg

  • Inhibition of PI3K/Akt signaling: an emerging paradigm for targeted cancer therapy.

    Yulong L. Chen;Ping-Yee Law;Horace H Loh

  • Expression of the μ-Opioid Receptor in CHO Cells: Ability of μ-Opioid Ligands to Promote α-Azidoanilido[32P]GTP Labeling of Multiple G Protein α Subunits

    Sumita Chakrabarti;Paul L. Prather;Lei Yu;Ping‐Yee ‐Y Law

  • Morphine Negatively Regulates Interferon-γ Promoter Activity in Activated Murine T Cells through Two Distinct Cyclic AMP-dependent Pathways

    Jinghua Wang;Roderick A. Barke;Richard Charboneau;Horace H. Loh

  • Mu-opioid receptors modulate the stability of dendritic spines

    Dezhi Liao;Hang Lin;Ping Yee Law;Horace H. Loh

  • Complementary DNA Cloning of a μ-Opioid Receptor from Rat Pertitoneal Macrophages

    M. Sedqi;S. Roy;S. Ramakrishnan;R. Elde

  • Morphine Regulates Dopaminergic Neuron Differentiation via miR-133b

    Fatima Macho Sanchez-Simon;Xiao Xiao Zhang;Horace H. Loh;Ping-Yee Law

Frequent Co-Authors

Ping-Yee Law
Ping-Yee Law University of Minnesota
Li-Na Wei
Li-Na Wei University of Minnesota
Sabita Roy
Sabita Roy University of Miami
Choon-Gon Jang
Choon-Gon Jang Sungkyunkwan University
Robert Elde
Robert Elde University of Minnesota
Volker Höllt
Volker Höllt Otto-von-Guericke University Magdeburg
Philip S. Portoghese
Philip S. Portoghese University of Minnesota
Axel Becker
Axel Becker Otto-von-Guericke University Magdeburg
Stanley A. Thayer
Stanley A. Thayer University of Minnesota
Hao Sun
Hao Sun Chinese University of Hong Kong

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