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Medicine

D-Index
81
Citations
21132
World Ranking
16775
National Ranking
880

Overview

Stefan Schulz is affiliated with Friedrich Schiller University Jena in Germany. Their research spans several scientific disciplines, predominantly within Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Schulz's work is especially concentrated in Molecular Biology and Cellular and Molecular Neuroscience, with contributions also touching on Epidemiology, Radiology, Nuclear Medicine and Imaging, and Endocrinology, Diabetes and Metabolism.

The scientist's main research topics include Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Neuroendocrine Tumor Research Advances, Monoclonal and Polyclonal Antibodies Research, Pain Mechanisms and Treatments, Pharmacological Receptor Mechanisms and Effects, and Pituitary Gland Disorders and Treatments.

Stefan Schulz has contributed to a range of journals and publication venues with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, IUPHAR/BPS Guide to Pharmacology CITE, Nature Communications, and Communications Biology.

The following recent papers authored or coauthored by Schulz illustrate the scope of their research:

  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists (2020, Science Signaling)
  • Morphine-induced respiratory depression is independent of β-arrestin2 signalling (2020, British Journal of Pharmacology)
  • Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor (2020, Trends in Pharmacological Sciences)
  • GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation (2022, Nature Communications)
  • Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis (2020, Molecular Therapy)

Schulz's collaborative research efforts include frequent co-authorship with the following colleagues:

  • Andrea Kliewer (16 joint publications)
  • Amelie Lupp (14 joint publications)
  • Sebastian Fritzwanker (13 joint publications)
  • Falko Nagel (12 joint publications)
  • Pooja Dasgupta (12 joint publications)

Best Publications

  • Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.

    John T. Williams;Susan L. Ingram;Graeme Henderson;Charles Chavkin

  • CXCR4 Regulates Interneuron Migration in the Developing Neocortex

    Ralf K. Stumm;Chun Zhou;Toshiaki Ara;Françoise Lazarini

  • A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia

    Ralf K. Stumm;Jutta Rummel;Vera Junker;Carsten Culmsee

  • Selective targeting of somatostatin receptor 3 to neuronal cilia

    M Händel;S Schulz;A Stanarius;M Schreff

  • Microbial volatile organic compounds in intra-kingdom and inter-kingdom interactions

    Laure Weisskopf;Stefan Schulz;Paolina Garbeva

  • Homo- and Heterodimerization of Somatostatin Receptor Subtypes INACTIVATION OF sst3 RECEPTOR FUNCTION BY HETERODIMERIZATION WITH sst2A

    Manuela Pfeiffer;Thomas Koch;Helmut Schröder;Marcus Klutzny

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Heterodimerization of Somatostatin and Opioid Receptors Cross-modulates Phosphorylation, Internalization, and Desensitization

    Manuela Pfeiffer;Thomas Koch;Helmut Schröder;Magdalena Laugsch

  • Cxcr7 controls neuronal migration by regulating chemokine responsiveness.

    Juan Antonio Sánchez-Alcañiz;Sammy Haege;Sammy Haege;Wiebke Mueller;Ramón Pla

  • Composition of Human Skin Microbiota Affects Attractiveness to Malaria Mosquitoes

    Niels O. Verhulst;Yu Tong Qiu;Hans Beijleveld;Chris Maliepaard

  • Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

    Anja Köster;Alexandra Montkowski;Stefan Schulz;Eva-Maria Stübe

  • Effect of the A118G polymorphism on binding affinity, potency and agonist‐mediated endocytosis, desensitization, and resensitization of the human mu‐opioid receptor

    Andrea Beyer;Thomas Koch;Helmut Schröder;Stefan Schulz

  • Identification of somatostatin receptor subtypes 1, 2A, 3, and 5 in neuroendocrine tumours with subtype specific antibodies.

    H Kulaksiz;R Eissele;D Rössler;S Schulz

  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists.

    Alexander Gillis;Arisbel B. Gondin;Andrea Kliewer;Julie Sanchez;Julie Sanchez

  • Carboxyl-terminal Splicing of the Rat μ Opioid Receptor Modulates Agonist-mediated Internalization and Receptor Resensitization

    Thomas Koch;Stefan Schulz;Helmut Schröder;Ronald Wolf

  • Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

    A. Kliewer;F. Schmiedel;S. Sianati;A. Bailey

  • Morphine induces terminal μ‐opioid receptor desensitization by sustained phosphorylation of serine‐375

    Stefan Schulz;Dana Mayer;Manuela Pfeiffer;Ralf Stumm

  • C-terminal Splice Variants of the Mouse µ-Opioid Receptor Differ in Morphine-induced Internalization and Receptor Resensitization *

    Thomas Koch;Stefan Schulz;Manuela Pfeiffer;Markus Klutzny

  • PET of CXCR4 expression by a (68)Ga-labeled highly specific targeted contrast agent.

    Eleni Gourni;Oliver Demmer;Margret Schottelius;Calogero D'Alessandria

  • Receptor endocytosis counteracts the development of opioid tolerance

    Thomas Koch;Antje Widera;Katharina Bartzsch;Stefan Schulz

Frequent Co-Authors

Udo Hahn
Udo Hahn Friedrich Schiller University Jena
Volker Höllt
Volker Höllt Otto-von-Guericke University Magdeburg
Alan L. Rector
Alan L. Rector University of Manchester
Christoph Röcken
Christoph Röcken Kiel University
Janna Hastings
Janna Hastings University College London
Rainer K. Reinscheid
Rainer K. Reinscheid University of California, Irvine
Christopher G. Chute
Christopher G. Chute Johns Hopkins University
Barry Smith
Barry Smith University at Buffalo, State University of New York
Ronald Cornet
Ronald Cornet University of Amsterdam
MacDonald J. Christie
MacDonald J. Christie University of Sydney

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