2026 Aedín C. Culhane: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	49	2593	2344	2	2	118	17676

Overview

Aedín C. Culhane is affiliated with the University of Limerick in Ireland and focuses their research on various aspects of biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields, including molecular biology, oncology, immunology, cancer research, and infectious diseases. The scientist's research interests encompass both broad and specialized topics within these disciplines.

The main research topics covered by Culhane include:

Single-cell and spatial transcriptomics
CAR-T cell therapy research
Gene expression and cancer classification
Cancer genomics and diagnostics
Protein degradation and inhibitors
COVID-19 clinical research studies
Immune cell function and interaction

Recent publications highlight Culhane's contributions to fields related to human microbiome research, oncology, and the safety and treatment of diseases such as rheumatoid arthritis and COVID-19. Key papers include:

Reporting guidelines for human microbiome research: the STORMS checklist, 2021, Nature Medicine
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence, 2021, Cancer Cell
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study, 2020, The Lancet Rheumatology
Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study, 2020, bioRxiv (Cold Spring Harbor Laboratory)
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study, 2020, Nature Communications

Their frequent co-authors reflect collaborations within cancer research and molecular biology:

Constantine S. Mitsiades
Ricardo de Matos Simoes
Eugen Dhimolea
Aviad Tsherniak
Sara Gandolfi

Culhane has published regularly in notable scientific venues, with multiple papers appearing in:

bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
Blood
UNC Libraries
Zenodo (CERN European Organization for Nuclear Research)

Their extensive publication record includes a significant number of studies within biochemistry, genetics, molecular biology (56 publications), and medicine (46 publications). The integration of diverse research areas indicates a multidisciplinary approach to understanding molecular and clinical aspects of disease, with emphasis on transcriptomics and cancer-related therapies.

Best Publications

The Immune Landscape of Cancer

Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

4501
Citations
Apoptosis: Molecular Regulation of Cell Death

Annette J. Hale;Christopher A. Smith;Leslie C. Sutherland;Victoria E. A. Stoneman

990
Citations
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

Bijan Sobhian;Genze Shao;Dana R. Lilli;Aedín C. Culhane

775
Citations
Repeatability of published microarray gene expression analyses.

John P A Ioannidis;David B Allison;Catherine A Ball;Issa Coulibaly

690
Citations
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data

Ian B Jeffery;Desmond G Higgins;Aedín C Culhane

521
Citations
Reporting guidelines for human microbiome research: the STORMS checklist

Chloe Mirzayi;Audrey Renson;Massive Analysis

423
Citations
MADE4: an R package for multivariate analysis of gene expression data

Aedín C. Culhane;Jean Thioulouse;Guy Perrière;Desmond G. Higgins

417
Citations
survcomp: an R/Bioconductor package for performance assessment and comparison of survival models

Markus S. Schröder;Aedín C. Culhane;John Quackenbush;Benjamin Haibe-Kains

413
Citations
A Three-Gene Model to Robustly Identify Breast Cancer Molecular Subtypes

Benjamin Haibe-Kains;Christine Desmedt;Sherene Loi;Aedin C. Culhane

381
Citations
Dimension reduction techniques for the integrative analysis of multi-omics data

Chen Meng;Oana A. Zeleznik;Gerhard G. Thallinger;Bernhard Küster

380
Citations
A multivariate approach to the integration of multi-omics datasets

Chen Meng;Bernhard Kuster;Bernhard Kuster;Aedín C Culhane;Amin Moghaddas Gholami

303
Citations
Between-group analysis of microarray data

Aedín C. Culhane;Guy Perrière;Elizabeth C. Considine;Thomas G. Cotter

285
Citations
Enter the Matrix: Factorization Uncovers Knowledge from Omics

Genevieve L. Stein-O’Brien;Raman Arora;Aedin C. Culhane;Alexander V. Favorov

252
Citations
Taxonomy of breast cancer based on normal cell phenotype predicts outcome

Sandro Santagata;Ankita Thakkar;Ayse Ergonul;Bin Wang

236
Citations
Risk Prediction for Late-Stage Ovarian Cancer by Meta-analysis of 1525 Patient Samples

Markus Riester;Wei Wei;Levi Waldron;Aedin C. Culhane

209
Citations
Gene Expression Atlas update—a value-added database of microarray and sequencing-based functional genomics experiments

Misha Kapushesky;Tomasz Adamusiak;Tony Burdett;Aedín C. Culhane

189
Citations
Cross-platform comparison and visualisation of gene expression data using co-inertia analysis.

Aedín C Culhane;Guy Perrière;Desmond G Higgins

187
Citations
Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification

M J Smith;Aedin Culhane;M Donovan;J C Coffey

185
Citations
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence.

Eugen Dhimolea;Ricardo de Matos Simoes;Dhvanir Kansara;Aziz Al’Khafaji

184
Citations
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue

Dung-Tsa Chen;Aejaz Nasir;Aedin Culhane;Chinnambally Venkataramu

179
Citations

Frequent Co-Authors

Constantine S. Mitsiades Harvard University

John Quackenbush Harvard University

William C. Hahn Dana-Farber Cancer Institute

Aviad Tsherniak Broad Institute

Benjamin Haibe-Kains Princess Margaret Cancer Centre

Benjamin L. Ebert Harvard University

Desmond G. Higgins University College Dublin

Francisca Vazquez Broad Institute

Lawrence H. Boise Emory University

Jonathan D. Licht University of Florida

External Links

Personal website of Aedín C. Culhane

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