World's Best Scientists 2026 revealed!
Desmond G. Higgins

Desmond G. Higgins

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
226875
World Ranking
6092
National Ranking
29

Research.com Recognitions

  • 2007 - Member of the Royal Irish Academy

Overview

Desmond G. Higgins is affiliated with University College Dublin in Ireland. Their research spans multiple fields, particularly focusing on Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's work covers several specialized subfields including Rheumatology, Molecular Biology, Genetics, Cancer Research, and Artificial Intelligence. These areas reflect a broad focus on understanding biological and medical processes at molecular and systemic levels.

Key topics central to their research include:

  • Osteoarthritis Treatment and Mechanisms
  • Mesenchymal stem cell research
  • Cancer-related molecular mechanisms research
  • Genomics and Phylogenetic Studies
  • RNA and protein synthesis mechanisms
  • Algorithms and Data Compression
  • GDF15 and Related Biomarkers

The scientist has contributed multiple papers to various academic venues. Notable recent publications include:

  • "Transcriptional profiling of early differentiation of primary human mesenchymal stem cells into chondrocytes," 2023, Scientific Data
  • "Transcriptional profiling of early differentiation of primary human mesenchymal stem cells into chondrocytes," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner," 2020, UNC Libraries
  • "CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer," 2020, UNC Libraries

Frequent collaborators include Thomas Schwarzl, Andrea Keogh, Georgina Shaw, Aleksandar Krstić, and Elizabeth Clayton. The scientist's work has appeared multiple times in venues such as UNC Libraries, Scientific Data, and bioRxiv (Cold Spring Harbor Laboratory).

Desmond G. Higgins has been recognized as a Member of the Royal Irish Academy since 2007.

Best Publications

  • CLUSTAL W: IMPROVING THE SENSITIVITY OF PROGRESSIVE MULTIPLE SEQUENCE ALIGNMENT THROUGH SEQUENCE WEIGHTING, POSITION-SPECIFIC GAP PENALTIES AND WEIGHT MATRIX CHOICE

    Julie D. Thompson;Desmond G. Higgins;Toby J. Gibson

  • The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.

    Julie D. Thompson;Toby J. Gibson;Frederica Plewniak;Francois Jeanmougin

  • Clustal W and Clustal X version 2.0

    M.A. Larkin;G. Blackshields;N.P. Brown;R. Chenna

  • Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

    Fabian Sievers;Andreas Wilm;David Dineen;Toby J Gibson

  • T-Coffee: A novel method for fast and accurate multiple sequence alignment.

    Cédric Notredame;Cédric Notredame;Cédric Notredame;Desmond G Higgins;Jaap Heringa

  • Multiple sequence alignment with the Clustal series of programs

    Ramu Chenna;Hideaki Sugawara;Tadashi Koike;Rodrigo Lopez

  • CLUSTAL: A package for performing multiple sequence alignment on a microcomputer

    Desmond G. Higgins;Paul M. Sharp

  • CLUSTAL V: improved software for multiple sequence alignment.

    Desmond G. Higgins;Alan J. Bleasby;Rainer Fuchs

  • Multiple sequence alignment with Clustal X

    François Jeanmougin;Julie D. Thompson;Manolo Gouy;Desmond G. Higgins

  • Fast and sensitive multiple sequence alignments on a microcomputer

    Desmond G. Higgins;Paul M. Sharp

  • USING CLUSTAL FOR MULTIPLE SEQUENCE ALIGNMENTS

    Desmond G Higgins;Julie D Thompson;Toby J Gibson

  • Clustal Omega for making accurate alignments of many protein sequences.

    Fabian Sievers;Desmond G. Higgins

  • Clustal Omega, accurate alignment of very large numbers of sequences.

    Fabian Sievers;Desmond G. Higgins

  • Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the considerable within-species diversity

    Paul M. Sharp;Elizabeth Cowe;Desmond G. Higgins;Denis C. Shields

  • SAGA: sequence alignment by genetic algorithm.

    Cédric Notredame;Desmond G. Higgins

  • M-Coffee : Combining multiple sequence alignment methods with T-Coffee

    Iain M. Wallace;Orla O'Sullivan;Desmond G. Higgins;Cedric Notredame

  • UNIT 3.13 Clustal Omega

    Fabian Sievers;Desmond G. Higgins

  • Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data

    Ian B Jeffery;Desmond G Higgins;Aedín C Culhane

  • Getting better with bifidobacteria

    S.C. Leahy;D.G. Higgins;G.F. Fitzgerald;D. van Sinderen

  • Finding flexible patterns in unaligned protein sequences.

    Inge Jonassen;John F. Collins;Desmond G. Higgins

Frequent Co-Authors

Denis C. Shields
Denis C. Shields University College Dublin
Norman E. Davey
Norman E. Davey Institute of Cancer Research
Cedric Notredame
Cedric Notredame Pompeu Fabra University
Toby J. Gibson
Toby J. Gibson European Bioinformatics Institute
Aedín C. Culhane
Aedín C. Culhane University of Limerick
Geraldine Butler
Geraldine Butler University College Dublin
Paul M. Sharp
Paul M. Sharp University of Edinburgh
Weifeng Shi
Weifeng Shi Shanghai Jiao Tong University
Chao-Dong Zhu
Chao-Dong Zhu Chinese Academy of Sciences
Walter Kolch
Walter Kolch University College Dublin

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Desmond G. Higgins

Trending Scientists

Recently Published Articles