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Genetics
Ireland
2026

D-Index & Metrics

Genetics

D-Index
68
Citations
19029
World Ranking
2419
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Genetics in Ireland Leader Award
  • 2025 - Research.com Genetics in Ireland Leader Award

Overview

Denis C. Shields is affiliated with University College Dublin in Ireland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Agricultural and Biological Sciences. Within these broader domains, their work deeply engages with subfields such as Molecular Biology, Plant Science, Food Science, Computational Theory and Mathematics, and Microbiology.

Their scholarly contributions encompass several main topics, including Probiotics and Fermented Foods, Computational Drug Discovery Methods, Legume Nitrogen Fixing Symbiosis, Agricultural pest management studies, Protein Hydrolysis and Bioactive Peptides, Antimicrobial Peptides and Activities, and Genomics and Phylogenetic Studies.

Denis C. Shields has collaborated frequently with a number of coauthors. These include Raúl Fernández-Díaz, Clement Agoni, Indrani Bera, Michael O'Sullivan, and Vanessa López.

Their research has been published in various scientific venues. Notable journals and platforms include Molecules, Royal Society Open Science, Preprints.org, bioRxiv (Cold Spring Harbor Laboratory), and Food Chemistry.

Recent papers authored or coauthored by Denis C. Shields include:

  • Relationship between Protein Digestibility and the Proteolysis of Legume Proteins during Seed Germination (2023) published in Molecules
  • Enriching antimicrobial peptides from milk hydrolysates using pectin/alginate food-gels (2021) published in Food Chemistry
  • Prediction of polyproline II secondary structure propensity in proteins (2020) published in Royal Society Open Science
  • Modelling the Transitioning of SARS-CoV-2 nsp3 and nsp4 Lumenal Regions towards a More Stable State on Complex Formation (2022) published in International Journal of Molecular Sciences
  • Relationship between Protein Digestibility and the Proteolysis of Legume Proteins during Seed Germination (2023) published in Preprints.org

Best Publications

  • Molecular evidence for an ancient duplication of the entire yeast genome

    Kenneth H. Wolfe;Denis C. Shields

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the considerable within-species diversity

    Paul M. Sharp;Elizabeth Cowe;Desmond G. Higgins;Denis C. Shields

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Towards the Improved Discovery and Design of Functional Peptides: Common Features of Diverse Classes Permit Generalized Prediction of Bioactivity

    Catherine Mooney;Niall J. Haslam;Gianluca Pollastri;Denis C. Shields

  • Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension

    Sandosh Padmanabhan;Olle Melander;Toby Johnson;Anna Maria Di Blasio

  • A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects

    A S Whitehead;P Gallagher;J L Mills;P N Kirke

  • Integration of Proteomics and Genomics in Platelets A PROFILE OF PLATELET PROTEINS AND PLATELET-SPECIFIC GENES

    James P. McRedmond;Stephen D. Park;Dermot F. Reilly;Judith A. Coppinger

  • Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

    Marcel Den Hoed;Mark Eijgelsheim;Tõnu Esko;Bianca J J M Brundel

  • Synonymous codon usage in Bacillus subtilis reflects both translational selection and mutational biases.

    Denis C. Shields;Paul M. Sharp

  • The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother

    Denis C. Shields;Peadar N. Kirke;James L. Mills;Dorothy Ramsbottom

  • Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

    Dawn L. Harmon;Denis C. Shields;Jayne V. Woodside;Dorothy McMaster

  • Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

    Folkert W. Asselbergs;Yiran Guo;Yiran Guo;Erik P A Van Iperen;Suthesh Sivapalaratnam

  • Cyclooxygenase‐1 haplotype modulates platelet response to aspirin

    A. O. Maree;R. J. Curtin;A. Chubb;C. Dolan

  • Homocysteine and Risk of Premature Coronary Heart Disease Evidence for a Common Gene Mutation

    Paula M. Gallagher;Raymond Meleady;Denis C. Shields;Kok Soon Tan

  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

    Richa Saxena;Richa Saxena;Clara C. Elbers;Clara C. Elbers;Yiran Guo;Inga Peter

  • A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

    Jillian P. Casey;Tiago R. Magalhães;Tiago R. Magalhães;Judith M. Conroy;Regina Regan

  • Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

    Philippa J. Talmud;Fotios Drenos;Sonia Shah;Tina Shah

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)

    HR Warren;E Evangelou;CP Cabrera;H Gao

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Norman E. Davey
Norman E. Davey Institute of Cancer Research
Desmond G. Higgins
Desmond G. Higgins University College Dublin
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Patricia B. Munroe
Patricia B. Munroe Queen Mary University of London
Peter S. Sever
Peter S. Sever Imperial College London
Mark J. Caulfield
Mark J. Caulfield Queen Mary University of London
Richard Edwards
Richard Edwards University of Otago
Sandosh Padmanabhan
Sandosh Padmanabhan University of Glasgow
Peter S. Braund
Peter S. Braund University of Leicester
Martin Farrall
Martin Farrall University of Oxford

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