World's Best Scientists 2026 revealed!

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Medicine

D-Index
144
Citations
150106
World Ranking
1400
National Ranking
141

Overview

Mark J. Caulfield is affiliated with Queen Mary University of London in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, reflecting a diverse engagement with genomic and medical sciences.

The scientist's publication record includes notable research on genetics and critical illness, especially in the context of COVID-19 and rare diseases. Among the recent papers authored or co-authored by them are:

  • Genetic mechanisms of critical illness in COVID-19, 2020, Nature
  • Whole-genome sequencing of patients with rare diseases in a national health system, 2020, Nature
  • Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank, 2020, Journal of Public Health
  • Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes, 2022, Nature
  • Genetic mechanisms of critical illness in Covid-19, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Mark J. Caulfield's frequent collaborators include:

  • Loukas Moutsianas
  • Richard H. Scott
  • Nirupa Murugaesu
  • Marta Bleda
  • Anna C. Need

The main publication venues for their work are diverse and include several high-visibility journals and preprint archives:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine
  • Nature Communications
  • Nature
  • The American Journal of Human Genetics

The scientist's fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad fields, the researcher specializes in several subfields:

  • Molecular Biology
  • Genetics
  • Cancer Research
  • Cardiology and Cardiovascular Medicine
  • Immunology

The principal topics addressed in their research include:

  • Genomics and Rare Diseases
  • Genomic variations and chromosomal abnormalities
  • Genetic Associations and Epidemiology
  • Mitochondrial Function and Pathology
  • Pharmacogenetics and Drug Metabolism
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer

Best Publications

  • 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

    Giuseppe Mancia;Robert Fagard;Krzysztof Narkiewicz;Josep Redon

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

    Peter S Sever;Björn Dahlöf;Neil R Poulter;Hans Wedel

  • Reappraisal of European guidelines on hypertension management:: A European Society of Hypertension Task Force document

    Giuseppe Mancia;Stéphane Laurent;Enrico Agabiti-Rosei;Ettore Ambrosioni

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Effects of Torcetrapib in Patients at High Risk for Coronary Events

    Philip J. Barter;Mark Caulfield;Mats Eriksson;Scott M Grundy

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial

    Björn Dahlöf;Peter S Sever;Neil R Poulter;Hans Wedel

  • Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

    Murray D. Esler;Henry Krum;Paul A. Sobotka;Markus P. Schlaich

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

    Cristen J. Willer;Elizabeth K. Speliotes;Elizabeth K. Speliotes;Ruth J. F. Loos;Shengxu Li

  • Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.

    Eleni Rapsomaniki;Adam Timmis;Julie George;Mar Pujades-Rodriguez

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Genetic mechanisms of critical illness in Covid-19.

    E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Modulation of genetic associations with serum urate levels by body-mass-index in humans

    Jennifer E. Huffman;Eva Albrecht;Alexander Teumer;Massimo Mangino

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Patricia B. Munroe
Patricia B. Munroe Queen Mary University of London
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Martin Farrall
Martin Farrall University of Oxford
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Anna F. Dominiczak
Anna F. Dominiczak University of Glasgow
Tonu Esko
Tonu Esko University of Tartu
Ruth J. F. Loos
Ruth J. F. Loos University of Copenhagen
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital

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