World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
87
Citations
25737
World Ranking
804
National Ranking
75

David W. Holden publication distribution in Microbiology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Microbiology in 2026. The highlighted bar marks where David W. Holden sits on this spectrum.

55–64 publications: 8 scientists 65–74 publications: 29 scientists 75–84 publications: 55 scientists 85–94 publications: 112 scientists 95–104 publications: 137 scientists 105–114 publications: 190 scientists 115–124 publications: 235 scientists 125–134 publications: 234 scientists 135–144 publications: 288 scientists 145–154 publications: 264 scientists 155–164 publications: 264 scientists 165–174 publications: 253 scientists 175–184 publications: 276 scientists 185–194 publications: 190 scientists 195–204 publications: 233 scientists 205–214 publications: 207 scientists 215–224 publications: 198 scientists 225–234 publications: 155 scientists 235–244 publications: 161 scientists 245–254 publications: 160 scientists 255–264 publications: 146 scientists 265–274 publications: 139 scientists 275–284 publications: 148 scientists 285–294 publications: 115 scientists 295–304 publications: 96 scientists 305–314 publications: 88 scientists 315–324 publications: 106 scientists 325–334 publications: 65 scientists 335–344 publications: 76 scientists 345–354 publications: 64 scientists 355–364 publications: 62 scientists 365–374 publications: 65 scientists 375–384 publications: 61 scientists 385–394 publications: 34 scientists 395–404 publications: 44 scientists 405–414 publications: 36 scientists 415–424 publications: 35 scientists 425–434 publications: 29 scientists 435–444 publications: 33 scientists 445–454 publications: 34 scientists 455–464 publications: 25 scientists 465–474 publications: 26 scientists 475–484 publications: 20 scientists 485–494 publications: 19 scientists 495–504 publications: 16 scientists 505–514 publications: 17 scientists 515–524 publications: 23 scientists 525–534 publications: 14 scientists 535–544 publications: 14 scientists 545–554 publications: 18 scientists 555–564 publications: 12 scientists 565–574 publications: 7 scientists 575–584 publications: 9 scientists 585–594 publications: 9 scientists 595–604 publications: 9 scientists 605–614 publications: 7 scientists 615–624 publications: 9 scientists 625–634 publications: 7 scientists 635–644 publications: 4 scientists 645–654 publications: 5 scientists 655–664 publications: 6 scientists 665–674 publications: 7 scientists 675–678 publications: 3 scientists 679+ publications: 99 scientists
55 publications 679+

This scientist: 176 publications — 39th percentile

39% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 679 publications or more.

David W. Holden D-index placement in Microbiology in 2026

The chart shows the D-index (discipline H-index) distribution of Microbiology scientists ranked by Research.com in 2026. The highlighted bar marks where David W. Holden sits on this spectrum.

40 D-Index: 30 scientists 41 D-Index: 86 scientists 42 D-Index: 90 scientists 43 D-Index: 117 scientists 44 D-Index: 122 scientists 45 D-Index: 123 scientists 46 D-Index: 108 scientists 47 D-Index: 110 scientists 48 D-Index: 106 scientists 49 D-Index: 109 scientists 50 D-Index: 129 scientists 51 D-Index: 111 scientists 52 D-Index: 116 scientists 53 D-Index: 127 scientists 54 D-Index: 134 scientists 55 D-Index: 134 scientists 56 D-Index: 111 scientists 57 D-Index: 136 scientists 58 D-Index: 162 scientists 59 D-Index: 151 scientists 60 D-Index: 139 scientists 61 D-Index: 122 scientists 62 D-Index: 126 scientists 63 D-Index: 144 scientists 64 D-Index: 109 scientists 65 D-Index: 103 scientists 66 D-Index: 124 scientists 67 D-Index: 112 scientists 68 D-Index: 103 scientists 69 D-Index: 131 scientists 70 D-Index: 93 scientists 71 D-Index: 93 scientists 72 D-Index: 96 scientists 73 D-Index: 92 scientists 74 D-Index: 80 scientists 75 D-Index: 66 scientists 76 D-Index: 87 scientists 77 D-Index: 60 scientists 78 D-Index: 73 scientists 79 D-Index: 59 scientists 80 D-Index: 57 scientists 81 D-Index: 55 scientists 82 D-Index: 47 scientists 83 D-Index: 77 scientists 84 D-Index: 50 scientists 85 D-Index: 45 scientists 86 D-Index: 42 scientists 87 D-Index: 41 scientists 88 D-Index: 32 scientists 89 D-Index: 38 scientists 90 D-Index: 35 scientists 91 D-Index: 34 scientists 92 D-Index: 27 scientists 93 D-Index: 26 scientists 94 D-Index: 33 scientists 95 D-Index: 22 scientists 96 D-Index: 37 scientists 97 D-Index: 22 scientists 98 D-Index: 21 scientists 99 D-Index: 22 scientists 100 D-Index: 30 scientists 101 D-Index: 16 scientists 102 D-Index: 20 scientists 103 D-Index: 17 scientists 104 D-Index: 19 scientists 105 D-Index: 16 scientists 106 D-Index: 19 scientists 107 D-Index: 18 scientists 108 D-Index: 14 scientists 109 D-Index: 10 scientists 110 D-Index: 9 scientists 111 D-Index: 7 scientists 112 D-Index: 11 scientists 113 D-Index: 6 scientists 114 D-Index: 15 scientists 115 D-Index: 10 scientists 116 D-Index: 12 scientists 117 D-Index: 7 scientists 118 D-Index: 10 scientists 119 D-Index: 10 scientists 120 D-Index: 11 scientists 121 D-Index: 2 scientists 122 D-Index: 7 scientists 123 D-Index: 12 scientists 124 D-Index: 5 scientists 125 D-Index: 9 scientists 126 D-Index: 6 scientists 127+ D-Index: 95 scientists
40 D-Index 127+

This scientist: 87 D-Index — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 127 D-Index or more.

Research.com Recognitions

  • 2004 - Fellow of the Royal Society, United Kingdom

Overview

David W. Holden is affiliated with Imperial College London in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus on Oncology, Genetics, Pathology and Forensic Medicine, Food Science, and Endocrinology.

The scientist's main topics of work include:

  • Multiple Sclerosis Research Studies
  • Salmonella and Campylobacter epidemiology
  • Polyomavirus and related diseases
  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • Cancer Research and Treatments
  • Escherichia coli research studies

David W. Holden has contributed to several recent publications. Notable papers include:

  • "Global mapping of Salmonella enterica-host protein-protein interactions during infection," 2021, Cell Host & Microbe
  • "The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules," 2020, Cell Host & Microbe
  • "CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD," 2021, PLoS Pathogens
  • "CSF neurofilament light chain testing as an aid to determine treatment strategies in MS," 2020, Neurology Neuroimmunology & Neuroinflammation
  • "Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism," 2021, Journal of Structural Biology

Frequent coauthors collaborating with David W. Holden include:

  • Gavin Giovannoni
  • Sharmilee Gnanapavan
  • Klaus Schmierer
  • Lucia Bianchi
  • Francesca Ammoscato

Their work appears regularly in several publication venues, with multiple contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Host & Microbe
  • PLoS Pathogens
  • Multiple Sclerosis and Related Disorders
  • Microbiology

In 2004, David W. Holden was awarded the distinction of Fellow of the Royal Society, United Kingdom.

Best Publications

  • Simultaneous identification of bacterial virulence genes by negative selection

    Michael Hensel;Jacqueline E. Shea;Colin Gleeson;Michael D. Jones

  • Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium

    Jacqueline E. Shea;Michael Hensel;Colin Gleeson;David W. Holden

  • Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages

    Michael Hensel;Jacqueline E. Shea;Scott R. Waterman;Rosanna Mundy

  • Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

    Sophie Helaine;Angela M. Cheverton;Kathryn G. Watson;Laura M. Faure

  • Salmonella maintains the integrity of its intracellular vacuole through the action of SifA.

    Carmen R. Beuzón;Stéphane Méresse;Kate E. Unsworth;Javier Ruíz-Albert

  • Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase.

    Andrés Vazquez-Torres;Yisheng Xu;Jessica Jones-Carson;David W. Holden

  • Identification of Staphylococcus aureus virulence genes in a murine model of bacteraemia using signature-tagged mutagenesis

    Ji-Min Mei;Fahimeh Nourbakhsh;Charles W. Ford;David W. Holden

  • A pneumococcal pilus influences virulence and host inflammatory responses

    M A Barocchi;J Ries;X Zogaj;C Hemsley

  • Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system.

    Scott R Waterman;David W Holden

  • Salmonella SPI-2 Type III Secretion System Effectors: Molecular Mechanisms And Physiological Consequences.

    Elliott Jennings;Teresa L.M. Thurston;David W. Holden

  • The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

    Jeremy S. Brown;Tracy Hussell;Sarah M. Gilliland;David W. Holden

  • Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors.

    Unknown

  • A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence

    Jeremy S. Brown;Sarah M. Gilliland;David W. Holden

  • Dynamics of intracellular bacterial replication at the single cell level

    Unknown

  • A functional genomic analysis of type 3 Streptococcus pneumoniae virulence.

    Gee W. Lau;Sauli Haataja;Michael Lonetto;Sarah E. Kensit

  • Gene transfer system for the phytopathogenic fungus Ustilago maydis

    Jun Wang;David W. Holden;Sally A. Leong

  • Complementary activities of SseJ and SifA regulate dynamics of the Salmonella typhimurium vacuolar membrane

    Javier Ruiz-Albert;Xiu-Jun Yu;Carmen R. Beuzón;Abigail N. Blakey

  • Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo.

    Suzana P. Salcedo;Mahdad Noursadeghi;Jonathan Cohen;David W. Holden

  • SseL, a Salmonella deubiquitinase required for macrophage killing and virulence

    Anne Rytkönen;John Poh;Junkal Garmendia;Cliona Boyle

  • In Vivo Genetic Analysis of Bacterial Virulence

    Su L. Chiang;John J. Mekalanos;David W. Holden

  • PH-DEPENDENT SECRETION OF SSEB, A PRODUCT OF THE SPI-2 TYPE III SECRETION SYSTEM OF SALMONELLA TYPHIMURIUM

    Carmen R. Beuzón;Geoff Banks;Jörg Deiwick;Michael Hensel

  • Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers.

    Zoë Hindle;Steven N. Chatfield;Jo Phillimore;Matthew Bentley

  • Salmonella Pathogenicity Island 2—Dependent Evasion of the

    Yisheng Xu;Jessica Jones-Carson;David W. Holden;Scott M. Lucia

Frequent Co-Authors

Michael Hensel
Michael Hensel Osnabrück University
Herbert N. Arst
Herbert N. Arst Imperial College London
Ferric C. Fang
Ferric C. Fang University of Washington
James C. Paton
James C. Paton University of Adelaide
Gordon Dougan
Gordon Dougan University of Cambridge
Christoph M. Tang
Christoph M. Tang University of Oxford
David Komander
David Komander Walter and Eliza Hall Institute of Medical Research
Stéphane Méresse
Stéphane Méresse Centre d’Immunologie de Marseille-Luminy
Hein te Riele
Hein te Riele Netherlands Cancer Institute
Gad Frankel
Gad Frankel Imperial College London

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