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Genetics

D-Index
78
Citations
18392
World Ranking
1720
National Ranking
220

Overview

Jay C. D. Hinton is affiliated with the University of Liverpool in the United Kingdom. Their research spans significant areas within biochemistry, genetics, and molecular biology, as well as agricultural and biological sciences. The scientist's work covers a range of subfields including food science, endocrinology, molecular biology, ecology, and infectious diseases.

The main topics of Jay C. D. Hinton's research reflect a focus on microbiology and bacterial genetics. These include:

  • Salmonella and Campylobacter epidemiology
  • Bacteriophages and microbial interactions
  • Vibrio bacteria research studies
  • Viral gastroenteritis research and epidemiology
  • Bacterial genetics and biotechnology
  • Genomics and phylogenetic studies
  • Escherichia coli research studies

Jay C. D. Hinton has contributed to numerous publications, including recent papers on bacterial pathogens and virus interactions. Selected papers include:

  • "Stepwise evolution of Salmonella Typhimurium ST313 causing bloodstream infection in Africa" (2020, Nature Microbiology)
  • "Prophages encode phage-defense systems with cognate self-immunity" (2021, Cell Host & Microbe)
  • "The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses" (2021, Nucleic Acids Research)
  • "Decoding the stoichiometric composition and organisation of bacterial metabolosomes" (2020, Nature Communications)
  • "An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes" (2021, Genome Biology)

The venues in which Jay C. D. Hinton frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Neglected Tropical Diseases
  • Nature Microbiology
  • Nature Communications
  • Microbial Genomics

Collaboration is a notable aspect of Jay C. D. Hinton's research, with frequent coauthors contributing to various projects. Regular collaborators include:

  • Blanca M. Perez-Sepulveda
  • Nicolas Wenner
  • Alexander V. Predeus
  • Nicholas Feasey
  • Caisey V. Pulford

Best Publications

  • Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica.

    Sofia Eriksson;Sacha Lucchini;Arthur Thompson;Mikael Rhen

  • Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation

    Matthew D. Rolfe;Matthew D. Rolfe;Christopher J. Rice;Sacha Lucchini;Carmen Pin

  • Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq.

    Alexandra Sittka;Sacha Lucchini;Kai Papenfort;Cynthia Mira Sharma

  • H-NS mediates the silencing of laterally acquired genes in bacteria.

    Sacha Lucchini;Gary Rowley;Martin D Goldberg;Douglas Hurd

  • An Infection-Relevant Transcriptomic Compendium for Salmonella enterica Serovar Typhimurium

    Carsten Kröger;Aoife Colgan;Shabarinath Srikumar;Kristian Händler

  • The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium

    Carsten Kröger;Shane C. Dillon;Andrew D. S. Cameron;Kai Papenfort

  • σE-dependent small RNAs of Salmonella respond to membrane stress by accelerating global omp mRNA decay

    Kai Papenfort;Verena Pfeiffer;Franziska Mika;Sacha Lucchini

  • Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation

    Verena Pfeiffer;Kai Papenfort;Sacha Lucchini;Jay C. D. Hinton;Jay C. D. Hinton

  • The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression.

    Thomas A. Owen-Hughes;Graham D. Pavitt;Diogenes S. Santos;Julie M. Sidebotham

  • Butyrate Specifically Down-Regulates Salmonella Pathogenicity Island 1 Gene Expression

    I. Gantois;R. Ducatelle;F. Pasmans;F. Haesebrouck

  • Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria

    Christopher S.J. Hulton;Alexander Seirafi;Jay C.D. Hinton;Julie M. Sidebotham

  • Bacterial genome size reduction by experimental evolution

    A I Nilsson;Sanna Koskiniemi;S Eriksson;E Kugelberg

  • SseL, a Salmonella deubiquitinase required for macrophage killing and virulence

    Anne Rytkönen;John Poh;Junkal Garmendia;Cliona Boyle

  • Single-copy green fluorescent protein gene fusions allow accurate measurement of Salmonella gene expression in vitro and during infection of mammalian cells.

    Isabelle Hautefort;Maria José Proença;Jay C. D. Hinton

  • The chromatin-associated protein H-NS alters DNA topology in vitro.

    A. E. Tupper;T. A. Owen-Hughes;D. W. Ussery;D. S. Santos

  • Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA

    Kai Papenfort;Nelly Said;Tim Welsink;Sacha Lucchini

  • Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA

    Cynthia M. Sharma;Kai Papenfort;Sandy R. Pernitzsch;Hans-Joachim Mollenkopf

  • RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium.

    Shabarinath Srikumar;Carsten Kröger;Carsten Kröger;Magali Hébrard;Aoife Colgan

  • Transcriptional Adaptation of Shigella flexneri during Infection of Macrophages and Epithelial Cells: Insights into the Strategies of a Cytosolic Bacterial Pathogen

    Sacha Lucchini;Hong Liu;Qi Jin;Jay C. D. Hinton

  • During infection of epithelial cells Salmonella enterica serovar Typhimurium undergoes a time-dependent transcriptional adaptation that results in simultaneous expression of three type 3 secretion systems.

    I Hautefort;A Thompson;S Eriksson-Ygberg;M L Parker

Frequent Co-Authors

Sacha Lucchini
Sacha Lucchini Earlham Institute
Melita A. Gordon
Melita A. Gordon University of Liverpool
Karsten Hokamp
Karsten Hokamp Trinity College Dublin
Neil Hall
Neil Hall Norwich Research Park
Christopher F. Higgins
Christopher F. Higgins Hammersmith Hospital
Jörg Vogel
Jörg Vogel University of Würzburg
Kai Papenfort
Kai Papenfort Friedrich Schiller University Jena
Charles J. Dorman
Charles J. Dorman Trinity College Dublin
Séamus Fanning
Séamus Fanning University College Dublin
Paul C. Driscoll
Paul C. Driscoll University College London

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