Christopher F. Higgins

Research.com Recognitions

• 2024 - Research.com Genetics in United Kingdom Leader Award
• 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
• 2023 - Research.com Genetics in United Kingdom Leader Award
• 1990 - Fellow of the Royal Society of Edinburgh

Overview

Best Publications

• ABC Transporters: From Microorganisms to Man

  Christopher F. Higgins

  7045
  Citations

• Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport.

  Stephen C. Hyde;Paul Emsley;Michael J. Hartshorn;Michael M. Mimmack

  1555
  Citations

• Multiple molecular mechanisms for multidrug resistance transporters

  Christopher F. Higgins

  1190
  Citations

• Is the multidrug transporter a flippase

  Christopher F. Higgins;Michael M. Gottesman

  1025
  Citations

• The ATP switch model for ABC transporters.

  Christopher F Higgins;Kenneth J Linton

  969
  Citations

• A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria.

  Higgins Cf;Hiles Id;Salmond Gp;Gill Dr

  910
  Citations

• ERIC sequences: a novel family of repetitive elements in the genomes of Escherichia coli, Salmonella typhimurium and other enterobacteria

  C. S. J. Hulton;C. F. Higgins;P. M. Sharp

  894
  Citations

• ABC transporters: physiology, structure and mechanism--an overview.

  Christopher F Higgins

  860
  Citations

• A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

  Christopher F Higgins;Charles J. Dorman;Douglas A. Stirling;Lesley Waddell

  841
  Citations

• Repetitive extragenic palindromic sequences: A major component of the bacterial genome

  Michael J. Stern;Giovanna Ferro-Luzzi Ames;Noel H. Smith;E. Clare Robinson

  803
  Citations

• A DEAD-box RNA helicase in the Escherichia coli RNA degradosome

  Béatrice Py;Christopher F. Higgins;Henry M. Krisch;Agamemnon J. Carpousis

  777
  Citations

• Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein.

  Miguel A. Valverde;Mario DÍaz;Francisco V. Sepúlveda;Deborah R. Gill

  681
  Citations

• The Escherichia coli ATP-binding cassette (ABC) proteins.

  Kenneth J. Linton;Christopher F. Higgins

  600
  Citations

• Communication between Multiple Drug Binding Sites on P-glycoprotein

  Catherine Martin;Georgina Berridge;Christopher F. Higgins;Prakash Mistry

  563
  Citations

• The ABC of channel regulation

  Christopher F Higgins

  541
  Citations

• Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

  Stephen C. Hyde;Deborah R. Gill;Christopher F. Higgins;Ann E. O. Trezise

  537
  Citations

• Structure of the Multidrug Resistance P-glycoprotein to 2.5 nm Resolution Determined by Electron Microscopy and Image Analysis

  Mark F. Rosenberg;Richard Callaghan;Robert C. Ford;Christopher F. Higgins

  519
  Citations

• Immunocytochemical localization of the cystic fibrosis gene product CFTR.

  Isabelle Crawford;Peter C. Maloney;Pamela L. Zeitlin;William B. Guggino

  507
  Citations

• Stabilization of translationally active mRNA by prokaryotic REP sequences

  Sarah F. Newbury;Noel H. Smith;E.Clare Robinson;Ian D. Hiles

  490
  Citations

• The human bile salt export pump: characterization of substrate specificity and identification of inhibitors.

  Jane A Byrne;Sandra S Strautnieks;Giorgina Mieli-Vergani;Christopher F Higgins

  428
  Citations