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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
15535
World Ranking
11811
National Ranking
908

Overview

Paul C. Driscoll is affiliated with University College London in the United Kingdom. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with significant contributions to Medicine. Key subfields of study include Cancer Research, Molecular Biology, Immunology, Biomedical Engineering, and Surgery.

The scientist's work covers topics such as Cancer, Hypoxia, and Metabolism; Epigenetics and DNA Methylation; Immune Cell Function and Interaction; T-cell and B-cell Immunology; COVID-19 epidemiological studies; SARS-CoV-2 and COVID-19 Research; and Infection Control and Ventilation.

Some of the recent papers authored or co-authored by Paul C. Driscoll are:

  • Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers, 2020, The Lancet
  • Identifying strategies to target the metabolic flexibility of tumours, 2020, Nature Metabolism
  • Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells, 2021, Nature Communications
  • The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells, 2021, Nature Communications
  • ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis, 2023, Cell Reports

Frequent co-authors collaborating with Driscoll include James I. MacRae, Nathalie Legrave, Sonia Gandhi, Rupert Beale, and Peter Cherepanov.

The scientist has published repeatedly in several venues, notably:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Lancet
  • Nature Metabolism
  • Cell Reports

Best Publications

  • Synthesis and Function of 3-Phosphorylated Inositol Lipids

    Bart Vanhaesebroeck;Sally J. Leevers;Khatereh Ahmadi;John Timms

  • Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1 beta

    Dominique Marion;Paul C. Driscoll;Lewis E. Kay;Paul T. Wingfield

  • Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

    K Salim;M J Bottomley;E Querfurth;M J Zvelebil

  • Analysis of the backbone dynamics of interleukin-1 beta using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy.

    G M Clore;P C Driscoll;P T Wingfield;A M Gronenborn

  • Solution structure of a DNA-binding domain from HMG1.

    Christopher M. Read;Peter D. Cary;Colyn Crane-Robinson;Paul C. Driscoll

  • The phosphatidylinositol 3-phosphate-binding FYVE finger

    Harald Alfred Stenmark;Rein Aasland;Paul C. Driscoll

  • Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.

    E. Y. Jones;K. Harlos;M. J. Bottomley;R. C. Robinson

  • Solution structure and ligand-binding site of the SH3 domain of the p85α subunit of phosphatidylinositol 3-kinase

    Grant W. Booker;Ivan Gout;A. Kristina^Downing;Paul C. Driscoll

  • Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers.

    Catherine F Houlihan;Nina Vora;Thomas Byrne;Dan Lewer

  • Assignment of the side-chain proton and carbon-13 resonances of interleukin-1.beta. using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy

    G. Clore;Ad Bax;Paul Driscoll;Paul Wingfield

  • Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.

    Ashley Jarvis;Charles K. Allerston;Haiyan Jia;Birger Herzog

  • Structure of domain 1 of rat T lymphocyte CD2 antigen

    Paul C. Driscoll;Jason G. Cyster;Iain D. Campbell;Alan F. Williams

  • H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein.

    Diego Esposito;Arsen Petrovic;Richard Harris;Shusuke Ono

  • Human epidermal growth factor. High resolution solution structure and comparison with human transforming growth factor alpha.

    Ulrich Hommel;Timothy S. Harvey;Paul C. Driscoll;Iain D. Campbell

  • Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

    Haiyan Jia;Azadeh Bagherzadeh;Basil Hartzoulakis;Ashley Jarvis

  • Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon.

    T D Bunney;R Harris;N L Gandarillas;M B Josephs

  • The OtsAB Pathway Is Essential for Trehalose Biosynthesis in Mycobacterium tuberculosis

    Helen N. Murphy;Graham R. Stewart;Vladimir V. Mischenko;Alexander S. Apt

  • Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins.

    B Kieffer;P C Driscoll;I D Campbell;A C Willis

  • 1H NMR assignment and secondary structure of the cell adhesion type III module of fibronectin.

    Martin Baron;Alison L. Main;Paul C. Driscoll;Helen J. Mardon

  • Solution structure of the fifth repeat of factor H: a second example of the complement control protein module.

    P. N. Barlow;D. G. Norman;A. Steinkasserer;T. J. Horne

Frequent Co-Authors

Iain D. Campbell
Iain D. Campbell University of Oxford
Michael D. Waterfield
Michael D. Waterfield Ludwig Cancer Research
John E. Ladbury
John E. Ladbury University of Leeds
Fraser A. Armstrong
Fraser A. Armstrong University of Oxford
Colyn Crane-Robinson
Colyn Crane-Robinson University of Portsmouth
Christopher F. Higgins
Christopher F. Higgins Hammersmith Hospital
Christina Redfield
Christina Redfield University of Oxford
Marketa Zvelebil
Marketa Zvelebil University of Basel
Alan F. Williams
Alan F. Williams University of Oxford
Jay C. D. Hinton
Jay C. D. Hinton University of Liverpool

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