World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
11829
World Ranking
13191
National Ranking
1030

Overview

Matilda Katan is affiliated with University College London in the United Kingdom. Their research spans several interconnected fields within the life sciences, primarily focusing on biochemistry, genetics, and molecular biology. Their work also intersects with immunology, microbiology, and medicine.

The main subfields of interest include molecular biology, immunology, surgery, cell biology, and cancer research. Katan's research encompasses diverse topics such as protein kinase regulation and GTPase signaling, cellular transport and secretion, fibroblast growth factor research, IL-33, ST2, and ILC pathways, congenital gastrointestinal and neural anomalies, cell death mechanisms and regulation, and neutrophil, myeloperoxidase, and oxidative mechanisms.

Frequent co-authors in their collaborations include Tom D. Bunney, Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, and Aaron Fleming.

The scientist has published multiple papers in notable journals and publication venues. Key recent papers include:

  • Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane, 2020, Essays in Biochemistry
  • Phospholipase C families: Common themes and versatility in physiology and pathology, 2020, Progress in Lipid Research

  • Cells of the human intestinal tract mapped across space and time, 2021, Nature
  • A small-molecule PI3Kα activator for cardioprotection and neuroregeneration, 2023, Nature
  • Severe Autoinflammatory Manifestations and Antibody Deficiency Due to Novel Hypermorphic PLCG2 Mutations, 2020, Journal of Clinical Immunology

Regarding publication venues, Katan has contributed frequently to bioRxiv (Cold Spring Harbor Laboratory), Nature, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Essays in Biochemistry, and Progress in Lipid Research.

Best Publications

  • Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta.

    Lars-Oliver Essen;Olga Perisic;Robert Cheung;Matilda Katan

  • Cells of the human intestinal tract mapped across space and time.

    Rasa Elmentaite;Natsuhiko Kumasaka;Kenny Roberts;Aaron Fleming

  • Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

    Bernward Hinkes;Roger C. Wiggins;Rasheed Gbadegesin;Christopher N. Vlangos

  • Multiple roles of phosphoinositide-specific phospholipase C isozymes.

    Pann-Ghill Suh;Jae-Il Park;Lucia Manzoli;Lucio Cocco

  • Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

    Michael J. Ombrello;Elaine F. Remmers;Guangping Sun;Alexandra F. Freeman

  • A Hypermorphic Missense Mutation in PLCG2, Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency

    Qing Zhou;Geun-Shik Lee;Geun-Shik Lee;Jillian Brady;Shrimati Datta

  • Recurrent PTPRB and PLCG1 mutations in angiosarcoma

    Sam Behjati;Sam Behjati;Patrick S Tarpey;Helen Sheldon;Inigo Martincorena

  • Rapid Global Fitting of Large Fluorescence Lifetime Imaging Microscopy Datasets

    Sean C. Warren;Anca Margineanu;Dominic Alibhai;Douglas J. Kelly

  • Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.

    Victoria Allen;Philip Swigart;Robert Cheung;Shamshad Cockcroft

  • Catalytic Domain of Phosphoinositide-specific Phospholipase C (PLC)

    Moira V. Ellis;Stephen R. James;Olga Perisic;C. Peter Downes

  • Replacements of Single Basic Amino Acids in the Pleckstrin Homology Domain of Phospholipase C-δ1 Alter the Ligand Binding, Phospholipase Activity, and Interaction with the Plasma Membrane

    Hitoshi Yagisawa;Kaori Sakuma;Hugh F. Paterson;Robert Cheung

  • Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities

    Matilda Katan;Ronald W. Kriz;Nicholas Totty;Robin Philp

  • A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.

    Lars-Oliver Essen;Olga Perisic;Denise E. Lynch;Matilda Katan

  • Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon.

    T D Bunney;R Harris;N L Gandarillas;M B Josephs

  • Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca2+ Entry

    Philipp Yu;Rainer Constien;Neil Dear;Matilda Katan

  • Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane.

    H F Paterson;J W Savopoulos;O Perisic;R Cheung

  • Purification of phosphoinositide-specific phospholipase C from a particulate fraction of bovine brain

    Matilda Katan;Peter J. Parker

  • Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex

    Matilda Katan;Alison Haigh;C.Peter Verrijzer;Peter C. van der Vliet

  • Dysfunction of phospholipase Cγ in immune disorders and cancer

    Hans Koss;Hans Koss;Tom D. Bunney;Sam Behjati;Matilda Katan

  • Multiplexed FRET to Image Multiple Signaling Events in Live Cells

    David M. Grant;Wei Zhang;Ewan J. McGhee;Tom D. Bunney

Frequent Co-Authors

John C. Marioni
John C. Marioni European Bioinformatics Institute
Roger L. Williams
Roger L. Williams University of Cambridge
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge
Muzlifah Haniffa
Muzlifah Haniffa Newcastle University
Holm H. Uhlig
Holm H. Uhlig University of Oxford
Simon R. Arridge
Simon R. Arridge University College London
Edward W. Tate
Edward W. Tate Imperial College London
Margaret J. Dallman
Margaret J. Dallman Imperial College London
Olga Perisic
Olga Perisic MRC Laboratory of Molecular Biology
Menna R. Clatworthy
Menna R. Clatworthy University of Cambridge

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to diverse career options, many of which are now accessible through online education. For students interested in health, fitness, or movement science, consider pursuing a kinesiology online degree—a rapidly growing field with relevance in rehabilitation, sports science, and wellness industries.

Nursing professionals looking to specialize can expand their qualifications with the shortest online pmhnp certificate programs, providing a pathway to advanced practice in mental health. Additionally, those holding nursing master’s degrees can pursue post masters fnp certification to become family nurse practitioners, broadening their clinical roles.

If nutrition and wellness spark your interest, you might consider a nutritionist degree online. This credential prepares graduates for roles in healthcare, food science, and public health. Each of these pathways offers flexibility and the opportunity to align your studies in biology or biochemistry with in-demand health and science careers.

Best Scientists Citing Matilda Katan

Trending Scientists

Recently Published Articles