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Immunology

D-Index
72
Citations
32308
World Ranking
2171
National Ranking
193

Overview

Holm H. Uhlig is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple disciplines with a focus on medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology.

The scientist's work is concentrated in key subfields including immunology, genetics, surgery, molecular biology, and infectious diseases. Their research topics reflect an emphasis on immunodeficiency and autoimmune disorders, inflammatory bowel disease, immune cell function and interaction, T-cell and B-cell immunology, digestive system health, microscopic colitis, as well as autoimmune and inflammatory disorders research.

Recent publications by Holm H. Uhlig include:

  • Short-chain fatty acids: linking diet, the microbiome and immunity (2024) published in Nature Reviews. Immunology
  • Cells of the human intestinal tract mapped across space and time (2021) published in Nature
  • IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies (2021) published in Nature Medicine
  • Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases (2020) published in Journal of Pediatric Gastroenterology and Nutrition
  • A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals (2020) published in Nature Immunology

Holm H. Uhlig has frequently published in several scientific journals, including:

  • Journal of Crohn's and Colitis
  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Clinical Immunology

The scientist has also collaborated extensively with other researchers; frequent co-authors include Dominik Aschenbrenner, Simon Travis, Scott B. Snapper, Fiona Powrie, and Aleixo M. Muise.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    Katrina M de Lange;Loukas Moutsianas;James C Lee;Christopher A Lamb

  • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

    Sofia Buonocore;Philip P. Ahern;Holm H. Uhlig;Ivaylo I. Ivanov

  • Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells.

    Christian Mottet;Holm H. Uhlig;Fiona Powrie

  • The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

    Julie Schulthess;Julie Schulthess;Sumeet Pandey;Melania Capitani;Kevin C. Rue-Albrecht

  • Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology

    Holm H. Uhlig;Brent S. McKenzie;Sophie Hue;Claire Thompson

  • Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease

    N R West;A N Hegazy;Owens Bmj.;S J Bullers

  • The diagnostic approach to monogenic very early onset inflammatory bowel disease.

    Holm H. Uhlig;Tobias Schwerd;Sibylle Koletzko;Neil Shah;Neil Shah

  • Cells of the human intestinal tract mapped across space and time.

    Rasa Elmentaite;Natsuhiko Kumasaka;Kenny Roberts;Aaron Fleming

  • Characterization of Foxp3 + CD4 + CD25 + and IL-10-Secreting CD4 + CD25 + T Cells during Cure of Colitis

    Holm H. Uhlig;Janine Coombes;Christian Mottet;Ana Izcue

  • Essential role for CD103 in the T cell–mediated regulation of experimental colitis

    Oliver Annacker;Janine L. Coombes;Vivianne Malmstrom;Holm H. Uhlig

  • A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

    Unknown

  • Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Jenny C. Taylor;Jenny C. Taylor;Hilary C. Martin;Stefano Lise;John Broxholme

  • Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

    Holm H Uhlig

  • Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.

    Cormac Cosgrove;James E. Ussher;Andri Rauch;Kathleen Gärtner

  • Regulatory T cells and intestinal homeostasis

    Janine L. Coombes;Nicholas J. Robinson;Kevin J. Maloy;Holm H. Uhlig;Holm H. Uhlig

  • Circulating and Tissue-Resident CD4 + T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

    Ahmed N. Hegazy;Ahmed N. Hegazy;Nathaniel R. West;Nathaniel R. West;Michael J.T. Stubbington;Michael J.T. Stubbington;Emily Wendt

  • Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

    Thomas Riffelmacher;Thomas Riffelmacher;Alexander Clarke;Felix C. Richter;Amanda Stranks

  • IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

    M Friedrich;M Pohin;M A Jackson;I Korsunsky

  • ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

    Claire Pearson;Claire Pearson;Emily E Thornton;Emily E Thornton;Brent McKenzie;Anna-Lena Schaupp;Anna-Lena Schaupp

  • Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells

    Renata Stepankova;Fiona Powrie;Olga Kofronova;Hana Kozakova

  • Control of intestinal inflammation by regulatory T cells.

    Christy Toms;Fiona Powrie

  • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology

    H H Uhlig;B S McKenzie;S Hue;C Thompson

Frequent Co-Authors

Fiona Powrie
Fiona Powrie University of Oxford
Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Simon Travis
Simon Travis University of Oxford
Sibylle Koletzko
Sibylle Koletzko University of Warmia and Mazury in Olsztyn
Aleixo M. Muise
Aleixo M. Muise University of Toronto
Wieland Kiess
Wieland Kiess Leipzig University
Arian Laurence
Arian Laurence University of Oxford
Carl A. Anderson
Carl A. Anderson Wellcome Sanger Institute
Dan Turner
Dan Turner Hebrew University of Jerusalem
Paul Klenerman
Paul Klenerman University of Oxford

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