Fiona Powrie

Research.com Recognitions

• 2025 - Research.com Best Female Scientists Award
• 2020 - Member of the National Academy of Sciences
• 2016 - Member of Academia Europaea
• 2011 - Fellow of the Royal Society, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)
• Fellow of The Academy of Medical Sciences, United Kingdom
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

  Janine L. Coombes;Karima R.R. Siddiqui;Carolina V. Arancibia-Cárcamo;Jason Hall

  3288
  Citations

• Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation.

  Simon Read;Vivianne Malmström;Fiona Powrie

  2831
  Citations

• Innate lymphoid cells--a proposal for uniform nomenclature.

  Hergen Spits;David Artis;Marco Colonna;Andreas Diefenbach

  2739
  Citations

• Intestinal homeostasis and its breakdown in inflammatory bowel disease

  Kevin J. Maloy;Fiona Powrie;Fiona Powrie

  2464
  Citations

• An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

  Chrystelle Asseman;Smita Mauze;Michael W. Leach;Robert L. Coffman

  2462
  Citations

• Innate Lymphoid Cells: 10 Years On.

  Eric Vivier;David Artis;Marco Colonna;Andreas Diefenbach

  2037
  Citations

• Regulatory T cells in the control of immune pathology.

  Kevin J. Maloy;Fiona Powrie

  1786
  Citations

• Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.

  Fiona Powrie;Michael W. Leach;Smita Mauze;Satish Menon

  1755
  Citations

• Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

  F Powrie;M W Leach;S Mauze;L B Caddle

  1687
  Citations

• A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells.

  F Powrie;J Carlino;M W Leach;S Mauze

  1372
  Citations

• Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

  Sofia Buonocore;Philip P. Ahern;Holm H. Uhlig;Ivaylo I. Ivanov

  1241
  Citations

• Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells.

  Christian Mottet;Holm H. Uhlig;Fiona Powrie

  1195
  Citations

• Interleukin-23 drives innate and T cell–mediated intestinal inflammation

  Sophie Hue;Philip P Ahern;Sofia Buonocore;Marika C. Kullberg

  1091
  Citations

• The alarmin IL-33 promotes regulatory T-cell function in the intestine

  Chris Schiering;Thomas Krausgruber;Agnieszka Chomka;Anja Fröhlich

  1058
  Citations

• CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms.

  Kevin J. Maloy;Laurence Salaun;Rachel Cahill;Gordon Dougan

  1002
  Citations

• IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

  Masaki Hara;Cherry I. Kingsley;Masanori Niimi;Simon Read

  1001
  Citations

• Dendritic cells in intestinal immune regulation

  Janine L. Coombes;Fiona Powrie

  987
  Citations

• The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

  Julie Schulthess;Julie Schulthess;Sumeet Pandey;Melania Capitani;Kevin C. Rue-Albrecht

  950
  Citations

• Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level.

  Giovanna Roncador;Philip J. Brown;Lorena Maestre;Sophie Hue

  873
  Citations

• Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

  Lydia Durant;Wendy T. Watford;Haydeé L. Ramos;Arian Laurence

  839
  Citations

• Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology

  Holm H. Uhlig;Brent S. McKenzie;Sophie Hue;Claire Thompson

  825
  Citations