2026 Heikki Rauvala: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	84	3288	3025	21	20	208	28210

Overview

Heikki Rauvala is affiliated with the University of Helsinki in Finland. Their research spans multiple areas within biochemistry, genetics, molecular biology, and neuroscience, with a particular focus on cellular and molecular neuroscience and cell biology.

The scientist's work concentrates extensively on topics including:

Proteoglycans and glycosaminoglycans research
Neuroscience and neuropharmacology research
Axon guidance and neuronal signaling
Nerve injury and regeneration
Advanced glycation end products research
Immunotherapy and immune responses
Immune cells in cancer

Heikki Rauvala's recent scholarly output includes contributions to various peer-reviewed journals. Notable papers feature:

"Regulation of Neurogenesis in Mouse Brain by HMGB1," published in 2020 in Cells
"Impact of JNK and Its Substrates on Dendritic Spine Morphology," published in 2020 in Cells
"Protective Role of Low Ethanol Administration Following Ischemic Stroke via Recovery of KCC2 and p75NTR Expression," published in 2020 in Molecular Neurobiology
"Low-Molecular Weight Protamine Overcomes Chondroitin Sulfate Inhibition of Neural Regeneration," published in 2022 in Frontiers in Cell and Developmental Biology
"Heparin-Binding Growth-Associated Molecule (Pleiotrophin) Affects Sensory Signaling and Selected Motor Functions in Mouse Model of Anatomically Incomplete Cervical Spinal Cord Injury," published in 2021 in Frontiers in Neurology

Research collaboration is a significant aspect of Rauvala's work. Frequent coauthors include:

Natalia Kulesskaya
Ari Rouhiainen
Ekaterina Mugantseva
Mikhail Paveliev
H. Benjamin Peng

Common publication venues for their research are:

Cells
UNC Libraries
Frontiers in Cell and Developmental Biology
Molecular Neurobiology
Frontiers in Neurology

Best Publications

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins.

Marika J Karkkainen;Paula Haiko;Kirsi Sainio;Juha Partanen

1746
Citations
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

Michael Jeltsch;Arja Kaipainen;Arja Kaipainen;Vladimir Joukov;Vladimir Joukov;Xiaojuan Meng;Xiaojuan Meng

1724
Citations
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

Xiaojuan Meng;Maria Lindahl;Mervi E. Hyvönen;Martti Parvinen

1723
Citations
Receptor for Advanced Glycation End Products (RAGE)-mediated Neurite Outgrowth and Activation of NF-κB Require the Cytoplasmic Domain of the Receptor but Different Downstream Signaling Pathways

Henri J. Huttunen;Carole Fages;Heikki Rauvala

953
Citations
Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation.

Henri J. Huttunen;Juha Kuja-Panula;Guglielmo Sorci;Anna Lisa Agneletti

773
Citations
An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors.

H. Rauvala

554
Citations
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock*

Jonas Sundén-Cullberg;Anna Norrby-Teglund;Ari Rouhiainen;Heikki Rauvala

545
Citations
Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies.

Vootele Võikar;Sulev Kõks;Eero Vasar;Heikki Rauvala

499
Citations
Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).

Y Fukushi;E Nudelman;S B Levery;S Hakomori

438
Citations
Long-term individual housing in C57BL/6J and DBA/2 mice: assessment of behavioral consequences.

V. Võikar;A. Polus;E. Vasar;H. Rauvala

420
Citations
High mobility group 1 B‐box mediates activation of human endothelium

C. J. Treutiger;G. E. Mullins;A.-S. M. Johansson;A. Rouhiainen;A. Rouhiainen

416
Citations
Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis

T.A. Mitsiadis;M. Salmivirta;T. Muramatsu;H. Muramatsu

400
Citations
Receptor for Advanced Glycation End Products-binding COOH-terminal Motif of Amphoterin Inhibits Invasive Migration and Metastasis

Henri J Huttunen;Carole Fages;Juha Kuja-Panula;Anne J Ridley

394
Citations
30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane.

J Merenmies;R Pihlaskari;J Laitinen;J Wartiovaara

376
Citations
Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3).

Erkki Raulo;Michael Chernousov;David Carey;Riitta Nolo

371
Citations
Molecular cloning of the 18-kDa growth-associated protein of developing brain.

J Merenmies;H Rauvala

365
Citations
Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons.

H Rauvala;R Pihlaskari

364
Citations
Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation.

J Parkkinen;E Raulo;J Merenmies;R Nolo

362
Citations
Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.

D.D.W. Cornelison;Sarah A. Wilcox-Adelman;Paul F. Goetinck;Heikki Rauvala

352
Citations
Retarded Growth and Deficits in the Enteric and Parasympathetic Nervous System in Mice Lacking GFRα2, a Functional Neurturin Receptor

Jari Rossi;Keijo Luukko;Dmitry Poteryaev;Antti Laurikainen

335
Citations