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D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
36198
World Ranking
2778
National Ranking
17

Medicine

D-Index
87
Citations
36220
World Ranking
13460
National Ranking
151

Overview

Dan Lindholm is a researcher affiliated with the Minerva Foundation in Finland with a focus on medicine, biochemistry, genetics, and molecular biology. Their work intersects multiple subfields including molecular biology, neurology, cell biology, cellular and molecular neuroscience, and infectious diseases.

The scientist's research primarily explores mechanisms related to endoplasmic reticulum stress and disease, autophagy in disease and therapy, amyotrophic lateral sclerosis research, genetic neurodegenerative diseases, sphingolipid metabolism and signaling, nerve injury and regeneration, and SARS-CoV-2 and COVID-19 research.

Their recent publications include:

  • ER stress and UPR in Alzheimer's disease: mechanisms, pathogenesis, treatments (2022) in Cell Death and Disease
  • Caspase-3-Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma (2022) in Cancer Research
  • Sphingolipids as Modulators of SARS-CoV-2 Infection (2021) in Frontiers in Cell and Developmental Biology
  • CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress (2023) in Brain
  • Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington's disease (2020) in Scientific Reports

Dan Lindholm has collaborated frequently with several coauthors, including Vignesh Srinivasan, Merja H. Voutilainen, Ove Eriksson, Laura Korhonen, and Maciej Łałowski.

Their publications have often appeared in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Scientific Reports, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cell and Developmental Biology, and Frontiers in Molecular Neuroscience.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve.

    Dan Lindholm;Rolf Heumann;Michael Meyer;Hans Thoenen

  • Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

    F Zafra;B Hengerer;J Leibrock;H Thoenen

  • ER stress and neurodegenerative diseases.

    Dan Lindholm;Hanna Wootz;Laura Korhonen

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages.

    Rolf Heumann;Dan Lindholm;Christine Bandtlow;Michael Meyer

  • Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.

    Francisco Zafra;Eero Castren;Hans Thoenen;Dan Lindholm

  • Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

    K. A. Stöckli;F. Lottspeich;M. Sendtner;P. Masiakowski

  • Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.

    Eero Castren;Francisco Zafra;Hans Thoenen;Dan Lindholm

  • Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation.

    D Lindholm;E Castrén;R Kiefer;F Zafra

  • Regulation of Nerve Growth Factor (NGF) Synthesis in the Rat Central Nervous System: Comparison between the Effects of Interleukin-1 and Various Growth Factors in Astrocyte Cultures and in vivo.

    Matthias Spranger;Dan Lindholm;Christine Bandtlow;Rolf Heumann

  • Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes

    F Zafra;D Lindholm;E Castren;J Hartikka

  • BRAIN-DERIVED NEUROTROPHIC FACTOR PROTECTS AGAINST ISCHEMIC CELL DAMAGE IN RAT HIPPOCAMPUS

    Thomas Beck;Dan Lindholm;Eero Castrén;Andreas Wree

  • The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus.

    Eero Castrén;Mervi Pitkänen;Jouni Sirviö;Alexander Parsadanian

  • Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos.

    Bastian Hengerer;Dan Lindholm;Rolf Heumann;Ulrich Ruther

  • Endoplasmic Reticulum Stress Inhibition Protects against Excitotoxic Neuronal Injury in the Rat Brain

    Anna-Leena Sokka;Noora Putkonen;Giuseppa Mudo;Evgeny Pryazhnikov

  • Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity.

    Dan Lindholm;Eero Castrén;Maria Berzaghi;Andrea Blöchl

  • Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity.

    Dan Lindholm;Georg Dechant;Carl-Philipp Heisenberg;Hans Thoenen

  • Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus.

    Marlies Knipper;Maria da Penha Berzaghi;Andrea Blöchl;Heinz Breer

  • Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

    Giuseppa Mudò;Johanna Mäkelä;Valentina Di Liberto;Timofey V. Tselykh

Frequent Co-Authors

Laura Korhonen
Laura Korhonen Linköping University
Hans Thoenen
Hans Thoenen Max Planck Society
Eero Castrén
Eero Castrén University of Helsinki
Rolf Heumann
Rolf Heumann Ruhr University Bochum
Stefan James
Stefan James Uppsala University
Natale Belluardo
Natale Belluardo University of Palermo
Lars Wallentin
Lars Wallentin Uppsala University
Agneta Siegbahn
Agneta Siegbahn Uppsala University
Michael Meyer
Michael Meyer University of Michigan–Ann Arbor
Giuseppa Mudò
Giuseppa Mudò University of Palermo

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