World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
80
Citations
21674
World Ranking
1626
National Ranking
34

Biology and Biochemistry

D-Index
80
Citations
21678
World Ranking
4112
National Ranking
272

Medicine

D-Index
80
Citations
21847
World Ranking
17184
National Ranking
549

Overview

Hiroyuki Nawa is affiliated with Wakayama Medical University in Japan and specializes in neuroscience and medicine. Their research presents a focus on both foundational and applied aspects of brain function and psychiatric disorders, particularly schizophrenia and neuropharmacology.

The scientist has extensively contributed to the fields of cellular and molecular neuroscience, biological psychiatry, molecular biology, cognitive neuroscience, and neurology. These broad research interests encompass the following main topics:

  • Tryptophan and brain disorders
  • Neuroscience and Neuropharmacology Research
  • Neuroendocrine regulation and behavior
  • Receptor Mechanisms and Signaling
  • Stress Responses and Cortisol
  • Neuropeptides and Animal Physiology
  • Neural dynamics and brain function

Recent publications reflect a consistent engagement with contemporary neuropsychiatric research. Notable papers include:

  • "Schizophrenia Animal Modeling with Epidermal Growth Factor and Its Homologs: Their Connections to the Inflammatory Pathway and the Dopamine System" (2023, Biomolecules)
  • "Resting-state dopaminergic cell firing in the ventral tegmental area negatively regulates affiliative social interactions in a developmental animal model of schizophrenia" (2021, Translational Psychiatry)
  • "USP10 Inhibits Aberrant Cytoplasmic Aggregation of TDP-43 by Promoting Stress Granule Clearance" (2022, Molecular and Cellular Biology)
  • "Inter-breeder differences in prepulse inhibition deficits of C57BL/6J mice in a maternal immune activation model" (2021, Neuropsychopharmacology Reports)
  • "ALDH4A1 expression levels are elevated in postmortem brains of patients with schizophrenia and are associated with genetic variants in enzymes related to proline metabolism" (2020, Journal of Psychiatric Research)

Hiroyuki Nawa frequently collaborates with a group of researchers, with the most common co-authors being:

  • Hisaaki Namba
  • Hidekazu Sotoyama
  • Hiroyoshi Inaba
  • Yuriko Iwakura
  • Akiyoshi Kakita

The scientist's work has been published in multiple venues, with repeated contributions to:

  • Neuropsychopharmacology Reports
  • Neurochemical Research
  • Scientific Reports
  • Clinical Neurophysiology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

    T Abe;H Sugihara;H Nawa;R Shigemoto

  • Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects

    Tommi Saarelainen;Panu Hendolin;Guilherme Lucas;Eija Koponen

  • Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor.

    Hiroyuki Nawa;Tadaaki Hirose;Hideaki Takashima;Seiichi Inayama

  • Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate.

    Y Nakajima;H Iwakabe;C Akazawa;H Nawa

  • Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats

    Makoto Mizuno;Kiyofumi Yamada;Ana Olariu;Hiroyuki Nawa

  • Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing.

    Hiroyuki Nawa;Hirokazu Kotani;Shigetada Nakanishi

  • Brain-Derived Neurotrophic Factor Induces Mammalian Target of Rapamycin-Dependent Local Activation of Translation Machinery and Protein Synthesis in Neuronal Dendrites

    Nobuyuki Takei;Naoko Inamura;Mihoko Kawamura;Hisaaki Namba

  • Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients.

    M Takahashi;O Shirakawa;K Toyooka;N Kitamura

  • BDNF PROTEIN MEASURED BY A NOVEL ENZYME IMMUNOASSAY IN NORMAL BRAIN AND AFTER SEIZURE : PARTIAL DISAGREEMENT WITH MRNA LEVELS

    Hiroyuki Nawa;Josette Carnahan;Christine Gall

  • Neuronal differentiation factors/cytokines and synaptic plasticity

    Paul H. Patterson;Hiroyuki Nawa

  • Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients.

    Kazuhiko Toyooka;Koue Asama;Yuichiro Watanabe;Tatsuyuki Muratake

  • mTOR signaling and its roles in normal and abnormal brain development

    Nobuyuki Takei;Hiroyuki Nawa

  • Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia

    Miki Bundo;Manabu Toyoshima;Yohei Okada;Wado Akamatsu

  • Structure and gene organization of bovine neuromedin K precursor.

    Hirokazu Kotani;Minoru Hoshimaru;Hiroyuki Nawa;Shigetada Nakanishi

  • Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons.

    Keiko Mizuno;Josette Carnahan;Hiroyuki Nawa

  • Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease

    Mako Narisawa-Saito;Koichi Wakabayashi;Shoji Tsuji;Hitoshi Takahashi

  • Cytokine hypothesis of schizophrenia pathogenesis: Evidence from human studies and animal models

    Yuichiro Watanabe;Toshiyuki Someya;Hiroyuki Nawa

  • Tyrosyl Phosphorylation of Shp2 Is Required for Normal ERK Activation in Response to Some, but Not All, Growth Factors

    Toshiyuki Araki;Hiroyuki Nawa;Benjamin G. Neel

  • Intraventricular Administration of Bdnf Increases Neuropeptide Expression in Newborn Rat-Brain

    Hiroyuki Nawa;Mary A. Pelleymounter;Josette Carnahan

  • Involvement of brain-derived neurotrophic factor in early retinal neuropathy of streptozotocin-induced diabetes in rats: therapeutic potential of brain-derived neurotrophic factor for dopaminergic amacrine cells.

    Masaaki Seki;Takayuki Tanaka;Hiroyuki Nawa;Tomoaki Usui

Frequent Co-Authors

Nobuyuki Takei
Nobuyuki Takei Niigata University
Akiyoshi Kakita
Akiyoshi Kakita Niigata University
Hitoshi Takahashi
Hitoshi Takahashi Niigata University
Kiyofumi Yamada
Kiyofumi Yamada Nagoya University
Toshitaka Nabeshima
Toshitaka Nabeshima Meijo University
Paul H. Patterson
Paul H. Patterson California Institute of Technology
Shigetada Nakanishi
Shigetada Nakanishi Kyoto University
Koichi Wakabayashi
Koichi Wakabayashi Hirosaki University
Norio Ozaki
Norio Ozaki Nagoya University
Tadao Arinami
Tadao Arinami University of Tsukuba

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