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Koichi Wakabayashi

Koichi Wakabayashi

D-Index & Metrics

Medicine

D-Index
88
Citations
26264
World Ranking
13243
National Ranking
392

Overview

Koichi Wakabayashi is affiliated with Hirosaki University in Japan and has contributed extensively to research in medicine and neuroscience, with a particular emphasis on neurology and cellular and molecular neuroscience. Their scholarly work spans multiple facets of neurological disorders, including Parkinson's disease, Alzheimer's disease, and other genetic neurodegenerative diseases.

The main topics in Wakabayashi's research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Amyotrophic Lateral Sclerosis Research
  • Genetic Neurodegenerative Diseases
  • Neurological diseases and metabolism
  • Neuroscience and Neuropharmacology Research

Wakabayashi's recent publications highlight a focused engagement with neuropathological mechanisms and clinical neuropathology. Selected recent papers include:

  • Where and how alpha-synuclein pathology spreads in Parkinson's disease: (2020), published in Neuropathology
  • Identification of multiple system atrophy mimicking Parkinson's disease or progressive supranuclear palsy (2021), Brain
  • Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice (2020), PLoS Genetics
  • Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome (2023), Brain Communications
  • GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming (2020), Neurobiology of Disease

The venues where Wakabayashi has published frequently include:

  • Neuropathology
  • Journal of Neuropathology & Experimental Neurology
  • Biochemical and Biophysical Research Communications
  • Brain Communications
  • Brain Pathology

Frequent collaborators of Wakabayashi demonstrate a network of partnership primarily with researchers such as Yasuo Miki, Fumiaki Mori, Masahiko Tomiyama, Tomoya Kon, and Kunikazu Tanji, contributing to multiple publications in overlapping research areas.

Their research outputs contribute broadly to understanding processes in neurodegeneration, cellular physiology, and molecular biology through empirical studies and clinical neuropathological investigations. This interdisciplinary approach supports insights into disease mechanisms and potential therapeutic strategies.

Best Publications

  • α-Synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

    Koichi Wakabayashi;Makoto Yoshimoto;Shoji Tsuji;Hitoshi Takahashi

  • Office of Rare Diseases neuropathologic criteria for corticobasal degeneration.

    Dennis W. Dickson;C. Bergeron;S. S. Chin;C. Duyckaerts

  • Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses

    K. Wakabayashi;H. Takahashi;S. Takeda;E. Ohama

  • Axonal α-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease

    Satoshi Orimo;Toshiki Uchihara;Ayako Nakamura;Fumiaki Mori

  • The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates.

    Koichi Wakabayashi;Kunikazu Tanji;Fumiaki Mori;Hitoshi Takahashi

  • Neuropathology of autonomic nervous system in Parkinson's disease.

    Koichi Wakabayashi;Hitoshi Takahashi

  • Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy.

    K. Wakabayashi;Shintaro Hayashi;Akiyoshi Kakita;Mitsunori Yamada

  • NACP/α-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson’s disease brains

    K. Wakabayashi;S. Hayashi;M. Yoshimoto;H. Kudo

  • Phosphorylated α-Synuclein Is Ubiquitinated in α-Synucleinopathy Lesions

    Masato Hasegawa;Hideo Fujiwara;Takashi Nonaka;Koichi Wakabayashi

  • The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders

    Koichi Wakabayashi;Kunikazu Tanji;Saori Odagiri;Yasuo Miki

  • NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

    Koichi Wakabayashi;Kayo Matsumoto;Kiyoshi Takayama;Makoto Yoshimoto

  • Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients.

    M Takahashi;O Shirakawa;K Toyooka;N Kitamura

  • Parkinson's disease : an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system

    K. Wakabayashi;H. Takahashi;E. Ohama;F. Ikuta

  • Lewy body-type degeneration in cardiac plexus in Parkinson's and incidental Lewy body diseases.

    K. Iwanaga;K. Wakabayashi;M. Yoshimoto;I. Tomita

  • Cardiac sympathetic denervation precedes neuronal loss in the sympathetic ganglia in Lewy body disease.

    Satoshi Orimo;Takeshi Amino;Yoshinori Itoh;Atsushi Takahashi

  • Degeneration of Cardiac Sympathetic Nerve Begins in the Early Disease Process of Parkinson’s Disease

    Satoshi Orimo;Atsushi Takahashi;Toshiki Uchihara;Fumiaki Mori

  • Synphilin-1 is present in Lewy bodies in Parkinson's disease.

    Koichi Wakabayashi;Simone Engelender;Makoto Yoshimoto;Shoji Tsuji

  • Selective Insolubility of α-Synuclein in Human Lewy Body Diseases Is Recapitulated in a Transgenic Mouse Model

    Philipp J. Kahle;Manuela Neumann;Laurence Ozmen;Veronika Müller

  • Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease

    Mako Narisawa-Saito;Koichi Wakabayashi;Shoji Tsuji;Hitoshi Takahashi

  • An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene.

    Shintaro Hayashi;Koichi Wakabayashi;Atsushi Ishikawa;Hiroko Nagai

Frequent Co-Authors

Hitoshi Takahashi
Hitoshi Takahashi Niigata University
Akiyoshi Kakita
Akiyoshi Kakita Niigata University
Tadaatsu Imaizumi
Tadaatsu Imaizumi Hirosaki University
Kei Satoh
Kei Satoh Hirosaki University
Shoji Tsuji
Shoji Tsuji University of Tokyo
Toshiki Uchihara
Toshiki Uchihara Tokyo Metropolitan Institute of Medical Science
Osamu Onodera
Osamu Onodera Niigata University
Akio Nakane
Akio Nakane Hirosaki University
Takeshi Ikeuchi
Takeshi Ikeuchi Niigata University
Ken Itoh
Ken Itoh Hirosaki University

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