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Biology and Biochemistry

D-Index
67
Citations
18145
World Ranking
8132
National Ranking
214

Overview

Rachel H. Giles is affiliated with Utrecht University in the Netherlands and has a research portfolio focused on medicine and biochemistry, genetics, and molecular biology. Their work extensively covers pulmonary and respiratory medicine, molecular biology, oncology, cancer research, and economics and econometrics.

Their main research topics include:

  • Renal cell carcinoma treatment
  • Economic and financial impacts of cancer
  • Renal and related cancers
  • Cancer genomics and diagnostics
  • Cancer immunotherapy and biomarkers
  • Genomics and rare diseases
  • Cancer, hypoxia, and metabolism

Rachel H. Giles has published frequently in the following scientific venues:

  • European Urology
  • Journal of Clinical Oncology
  • European Urology Open Science
  • Annals of Oncology
  • Cancer

Some of their recent papers include:

  • Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Nivolumab plus Cabozantinib Joins Immune Checkpoint Inhibition Combination Therapies for Treatment-naïve Metastatic Clear-Cell Renal Cell Carcinoma, 2020, European Urology
  • Limitations of Available Studies Prevent Reliable Comparison Between Tumour Ablation and Partial Nephrectomy for Patients with Localised Renal Masses: A Systematic Review from the European Association of Urology Renal Cell Cancer Guideline Panel, 2020, European Urology Oncology
  • Axitinib plus immune checkpoint inhibitor: evidence- and expert-based consensus recommendation for treatment optimisation and management of related adverse events, 2020, British Journal of Cancer
  • 2021 Updated European Association of Urology Guidelines on the Use of Adjuvant Pembrolizumab for Renal Cell Carcinoma, 2021, European Urology
  • CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase, 2022, Nucleic Acids Research

Frequent co-authors collaborating with Giles include:

  • Axel Bex
  • Laurence Albigès
  • Lorenzo Marconi
  • Saeed Dabestani
  • Börje Ljungberg

Best Publications

  • Caught up in a Wnt storm: Wnt signaling in cancer.

    Rachel H. Giles;Johan H. van Es;Hans Clevers

  • Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

    Fred Petrif;Rachel H. Giles;Hans G. Dauwerse;Jasper J. Saris

  • European Association of Urology Guidelines on Renal Cell Carcinoma: The 2019 Update.

    Börje Ljungberg;Laurance Albiges;Yasmin Abu-Ghanem;Karim Bensalah

  • Mutations in the APC tumour suppressor gene cause chromosomal instability

    Riccardo Fodde;Jeroen Kuipers;Jeroen Kuipers;Carla Rosenberg;Ron Smits

  • Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

    Liyun Sang;Julie J. Miller;Kevin C. Corbit;Rachel H. Giles

  • Conjunction dysfunction: CBP/p300 in human disease

    Rachel H Giles;Dorien J.M Peters;Martijn H Breuning

  • Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

    Moumita Chaki;Rannar Airik;Amiya K. Ghosh;Rachel H. Giles

  • Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

    Edgar A Otto;Toby W Hurd;Rannar Airik;Moumita Chaki

  • Genetic analysis of von Hippel-Lindau disease.

    Morgan Nordstrom-O'Brien;Rob B. van der Luijt;Ellen van Rooijen;Ans M. van den Ouweland

  • Genetic, environmental, and epigenetic factors involved in CAKUT

    Nayia Nicolaou;Kirsten Y Renkema;Ernie M H F Bongers;Rachel H Giles

  • FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

    Weibin Zhou;Edgar A Otto;Andrew Cluckey;Rannar Airik

  • Updated European Association of Urology Guidelines on Renal Cell Carcinoma : Immune Checkpoint Inhibition Is the New Backbone in First-line Treatment of Metastatic Clear-cell Renal Cell Carcinoma

    Laurence Albiges;Tom Powles;Michael Staehler;Karim Bensalah

  • An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

    Gabrielle Wheway;Miriam Schmidts;Dorus A. Mans;Katarzyna Szymanska

  • Human Embryonic Mesenchymal Stem Cell-Derived Conditioned Medium Rescues Kidney Function in Rats with Established Chronic Kidney Disease

    Arianne van Koppen;Jaap A. Joles;Bas W. M. van Balkom;Sai Kiang Lim

  • An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

    Boldt K;van Reeuwijk J;Lu Q;Koutroumpas K

  • Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis

    Sander G Basten;Rachel H Giles

  • The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium

    Teunis Jp van Dam;Gabrielle Wheway;Gisela G Slaats;Martijn A Huynen

  • Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer

    Thomas Powles;Laurence Albiges;Michael Staehler;Karim Bensalah

  • The many faces of the tumor suppressor gene APC.

    Johan H. van Es;Rachel H. Giles;Hans C. Clevers

  • Von Hippel-Lindau Disease: Genetics and Role of Genetic Counseling in a Multiple Neoplasia Syndrome

    Sarah M Nielsen;Lindsay Rhodes;Ignacio Guillermo Blanco;Wendy K Chung

Frequent Co-Authors

Emile E. Voest
Emile E. Voest Antoni van Leeuwenhoek Hospital
Nine V.A.M. Knoers
Nine V.A.M. Knoers University Medical Center Groningen
Thomas Powles
Thomas Powles Queen Mary University of London
Ronald Roepman
Ronald Roepman Radboud University
Börje Ljungberg
Börje Ljungberg Umeå University
Laurence Albiges
Laurence Albiges Institut Gustave Roussy
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Colin A. Johnson
Colin A. Johnson University of Leeds
marius ueffing
marius ueffing University of Tübingen
Martijn H. Breuning
Martijn H. Breuning Leiden University Medical Center

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