D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 47 Citations 10,788 91 World Ranking 11653 National Ranking 268

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • DNA

The scientist’s investigation covers issues in Genetics, Cell biology, Cilium, Ciliopathies and Renal cell carcinoma. With her scientific publications, her incorporates both Genetics and CREB-binding protein. Her studies deal with areas such as Tumor suppressor gene and Zebrafish as well as Cell biology.

The concepts of her Cilium study are interwoven with issues in Cystic kidney and Organelle. Her Ciliopathies research is multidisciplinary, incorporating perspectives in Human genetics, Ciliopathy and Polycystic kidney disease. In her study, Sunitinib is strongly linked to Urology, which falls under the umbrella field of Renal cell carcinoma.

Her most cited work include:

  • Caught up in a Wnt storm: Wnt signaling in cancer. (1295 citations)
  • Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP (1025 citations)
  • Mutations in the APC tumour suppressor gene cause chromosomal instability (611 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Genetics, Cilium, Cell biology, Cancer research and Internal medicine. Her Genetics research integrates issues from Molecular biology and Disease. Her Cilium research also works with subjects such as

  • Ciliopathy which intersects with area such as Ciliopathies, Nephronophthisis and Joubert syndrome,
  • DNA damage and related Cell cycle.

Rachel H. Giles interconnects Suppressor and Zebrafish in the investigation of issues within Cell biology. The study incorporates disciplines such as Tumor suppressor gene, Cancer, Wnt signaling pathway and Von Hippel–Lindau disease in addition to Cancer research. Her Internal medicine research is multidisciplinary, incorporating elements of Endocrinology and Oncology.

She most often published in these fields:

  • Genetics (24.39%)
  • Cilium (23.17%)
  • Cell biology (21.95%)

What were the highlights of her more recent work (between 2015-2021)?

  • Renal cell carcinoma (10.98%)
  • Kidney cancer (9.15%)
  • Internal medicine (18.29%)

In recent papers she was focusing on the following fields of study:

Rachel H. Giles mainly focuses on Renal cell carcinoma, Kidney cancer, Internal medicine, Cell biology and Cilium. Her study looks at the intersection of Internal medicine and topics like Oncology with Frameshift mutation. Her work carried out in the field of Cell biology brings together such families of science as Transgene and Zebrafish.

Her studies in Cilium integrate themes in fields like Phenotype, Ciliopathies, Ciliopathy and Ciliary tip. The subject of her Phenotype research is within the realm of Genetics. Her study on Genetics is mostly dedicated to connecting different topics, such as Disease.

Between 2015 and 2021, her most popular works were:

  • European Association of Urology Guidelines on Renal Cell Carcinoma: The 2019 Update. (329 citations)
  • An organelle-specific protein landscape identifies novel diseases and molecular mechanisms (126 citations)
  • Updated European Association of Urology Guidelines: Recommendations for the Treatment of First-line Metastatic Clear Cell Renal Cancer (105 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

The scientist’s investigation covers issues in Renal cell carcinoma, Genetics, Urology, Kidney cancer and Sunitinib. Genetics and Disease are frequently intertwined in her study. Rachel H. Giles combines subjects such as Cancer, Systematic review, Clear cell renal cell carcinoma and Guideline with her study of Urology.

Her work deals with themes such as Randomized controlled trial and Adjuvant therapy, which intersect with Kidney cancer. Her work investigates the relationship between Molecular genetics and topics such as Phenotype that intersect with problems in Cilium. Her research investigates the connection between Ciliary transition zone and topics such as Cell biology that intersect with problems in Intraflagellar transport.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Caught up in a Wnt storm: Wnt signaling in cancer.

Rachel H. Giles;Johan H. van Es;Hans Clevers.
Biochimica et Biophysica Acta (2003)

1895 Citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

Fred Petrif;Rachel H. Giles;Hans G. Dauwerse;Jasper J. Saris.
Nature (1995)

1326 Citations

Mutations in the APC tumour suppressor gene cause chromosomal instability

Riccardo Fodde;Jeroen Kuipers;Jeroen Kuipers;Carla Rosenberg;Ron Smits.
Nature Cell Biology (2001)

882 Citations

Conjunction dysfunction: CBP/p300 in human disease

Rachel H Giles;Dorien J.M Peters;Martijn H Breuning.
Trends in Genetics (1998)

517 Citations

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

Liyun Sang;Julie J. Miller;Kevin C. Corbit;Rachel H. Giles.
Cell (2011)

489 Citations

European Association of Urology Guidelines on Renal Cell Carcinoma: The 2019 Update.

Börje Ljungberg;Laurance Albiges;Yasmin Abu-Ghanem;Karim Bensalah.
European Urology (2019)

442 Citations

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

Moumita Chaki;Rannar Airik;Amiya K. Ghosh;Rachel H. Giles.
Cell (2012)

387 Citations

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

Edgar A Otto;Toby W Hurd;Rannar Airik;Moumita Chaki.
Nature Genetics (2010)

325 Citations

Genetic analysis of von Hippel-Lindau disease.

Morgan Nordstrom-O'Brien;Rob B. van der Luijt;Ellen van Rooijen;Ans M. van den Ouweland.
Human Mutation (2010)

277 Citations

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Weibin Zhou;Edgar A Otto;Andrew Cluckey;Rannar Airik.
Nature Genetics (2012)

204 Citations

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