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Ernest C. Borden

Ernest C. Borden

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
31216
World Ranking
2314
National Ranking
1239

Medicine

D-Index
92
Citations
32102
World Ranking
11279
National Ranking
5791

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Ernest C. Borden is affiliated with the Cleveland Clinic in the United States. Their research focuses primarily on the fields of Medicine, with specific work in Oncology and Infectious Diseases. The main topics covered in their work include COVID-19 and healthcare impacts, COVID-19 clinical research studies, and cancer immunotherapy and biomarkers.

Borden has published research in notable venues, including the Journal for ImmunoTherapy of Cancer. One of their recent papers, published in 2020, is titled Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19, which contributes to understanding immuno-oncology and therapeutic access during the pandemic.

Frequent co-authors collaborating with Borden include:

  • Paolo A. Ascierto
  • Bernard A. Fox
  • Walter J. Urba
  • Ana C. Anderson
  • Michael B. Atkins

Borden has explored topics that intersect cancer treatment and infectious disease responses, particularly in the context of COVID-19. Their contributions address both clinical research studies related to COVID-19 and biomarker development in cancer immunotherapy.

In recognition of their contributions to science, Ernest C. Borden was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

    John M. Kirkwood;Myla Hunt Strawderman;Marc S. Ernstoff;Thomas J. Smith

  • Interferons at age 50: past, current and future impact on biomedicine.

    Ernest C Borden;Ganes Sen;Gilles Uze;Robert H Silverman

  • Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033

    Charles D. Blanke;Cathryn Rankin;George D. Demetri;Christopher W. Ryan

  • Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis.

    Mamta Chawla-Sarkar;Daniel J Lindner;Y-F Liu;Bryan Raymond George Williams

  • Circulating Tumor Cells versus Imaging—Predicting Overall Survival in Metastatic Breast Cancer

    G. Thomas Budd;Massimo Cristofanilli;Mathew J. Ellis;Allison Stopeck

  • Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group.

    Michael C. Heinrich;Kouros Owzar;Christopher L. Corless;Donna Hollis

  • Inhibition of Angiogenesis by Interferons: Effects on Tumor-and Lymphocyte-induced Vascular Responses

    Younan A. Sidky;Ernest C. Borden

  • Biological Properties of Recombinant α-Interferons: 40th Anniversary of the Discovery of Interferons

    Lawrence M. Pfeffer;Charles A. Dinarello;Ronald B. Herberman;Bryan R. G. Williams

  • Soft Tissue Sarcomas of Adults State of the Translational Science

    Ernest C. Borden;Laurence H. Baker;Robert S. Bell;Vivien Bramwell

  • Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

    Xiaoxia Z. West;Nikolay L. Malinin;Alona A. Merkulova;Mira Tischenko

  • Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis.

    M Chawla-Sarkar;S I Bae;F J Reu;B S Jacobs

  • IMMUNOREGULATORY PROPERTIES OF ISG15, AN INTERFERON-INDUCED CYTOKINE

    Jonathan D'Cunha;Ernest Knight;Arthur L. Haas;Robert L. Truitt

  • Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

    Baisakhi Raychaudhuri;Patricia Rayman;Joanna Ireland;Jennifer Ko

  • Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas.

    E C Borden;D A Amato;C Rosenbaum;H T Enterline

  • Interferons α and β in cancer: therapeutic opportunities from new insights.

    Ernest C Borden

  • Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines.

    Mamta Chawla-Sarkar;Douglas W. Leaman;Ernest C. Borden

  • Human Polyomavirus Infections with JC Virus and BK Virus in Renal Transplant Patients

    Thomas F. Hogan;Ernest C. Borden;J. A. McBAIN;B. L. Padgett

  • High-throughput Immunoblotting UBIQUITIN-LIKE PROTEIN ISG15 MODIFIES KEY REGULATORS OF SIGNAL TRANSDUCTION

    Michael P. Malakhov;Keun Il Kim;Oxana A. Malakhova;Barbara S. Jacobs

  • In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine.

    Jonathan D'Cunha;Sujatha Ramanujam;Randall J. Wagner;Patricia L. Witt

  • Inhibition of Murine Tumor Growth by an Interferon-inducing Imidazoquinolinamine

    Younan A. Sidky;Ernest C. Borden;Charles E. Weeks;Michael J. Reiter

Frequent Co-Authors

Joan H. Schiller
Joan H. Schiller University of Virginia
George D. Demetri
George D. Demetri Dana-Farber Cancer Institute
Gerald I. Byrne
Gerald I. Byrne University of Tennessee Health Science Center
David Goldstein
David Goldstein University of New South Wales
Brian I. Rini
Brian I. Rini Vanderbilt University Medical Center
Paul M. Sondel
Paul M. Sondel University of Wisconsin–Madison
Christopher D.M. Fletcher
Christopher D.M. Fletcher Brigham and Women's Hospital
Charles D. Blanke
Charles D. Blanke Oregon Health & Science University
James K V Willson
James K V Willson The University of Texas at Dallas
Robert S. Benjamin
Robert S. Benjamin The University of Texas MD Anderson Cancer Center

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