High frequency of mutations of the PIK3CA gene in human cancers
Yardena Samuels;Zhenghe Wang;Alberto Bardelli;Natalie Silliman.
Science (2004)
3990 Citations
Inactivation of the Type II TGF-β Receptor in Colon Cancer Cells with Microsatellite Instability
Sanford D Markowitz;Jing Wang;Lois Myeroff;Ramon Parsons.
Science (1995)
3015 Citations
Suppression of human colorectal carcinoma cell growth by wild-type p53.
Suzanne J. Baker;Sanford D Markowitz;Eric R. Fearon;James K V Willson.
Science (1990)
2414 Citations
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
James G. Herman;Asad Umar;Kornelia Polyak;Jeremy R. Graff.
Proceedings of the National Academy of Sciences of the United States of America (1998)
2325 Citations
Mutations of mitotic checkpoint genes in human cancers
Daniel P. Cahill;Christoph Lengauer;Jian Yu;Gregory J. Riggins.
Nature (1998)
1913 Citations
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
Suzanne J. Baker;Antonette C. Preisinger;J. M. Jessup;Christos Paraskeva.
Cancer Research (1990)
1464 Citations
Somatic mutations of the mitochondrial genome in human colorectal tumours
Kornelia Polyak;Kornelia Polyak;Yunbo Li;Hong Zhu;Christoph Lengauer.
Nature Genetics (1998)
1022 Citations
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
Ramon Parsons;Lois L. Myeroff;Bo Liu;James K. V. Willson.
Cancer Research (1995)
1015 Citations
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
Bo Liu;Nicholas C. Nicolaides;Sanford Markowitz;James K.V. Willson.
Nature Genetics (1995)
958 Citations
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Jihye Yun;Carlo Rago;Ian Cheong;Ray Pagliarini;Ray Pagliarini.
Science (2009)
925 Citations
