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D-Index
87
Citations
29956
World Ranking
13576
National Ranking
6903

Overview

Stanton L. Gerson is affiliated with Case Western Reserve University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad areas, Gerson's work focuses on subfields such as Molecular Biology, Hematology, Immunology, Oncology, and Epidemiology.

The scientist's main topics of research include Hematopoietic Stem Cell Transplantation, Peptidase Inhibition and Analysis, Chronic Myeloid Leukemia Treatments, DNA Repair Mechanisms, T-cell and B-cell Immunology, Tuberculosis Research and Epidemiology, and the Diagnosis and Treatment of Tuberculosis.

Gerson's recent publications feature a mix of topics relevant to inflammation, cancer survival, DNA repair, and hematopoiesis. Notable papers include:

  • Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation, 2020, Nature Communications
  • Socioeconomic Factors and Survival of Multiple Myeloma Patients, 2021, Cancers
  • An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation, 2021, Progress in Biophysics and Molecular Biology
  • 15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration, 2021, JCI Insight
  • Phase I clinical trial of temozolomide and methoxyamine (TRC-102), an inhibitor of base excision repair, in patients with advanced solid tumors, 2020, Investigational New Drugs

Frequent collaborators in Gerson's research include Amar Desai, Julianne Smith, Sanford D. Markowitz, Kelsey F. Christo, and Alvin Jogasuria.

Their work has been published in key venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Clinical Oncology, Blood, Experimental Hematology, and Nature Communications.

Best Publications

  • Rapid Hematopoietic Recovery After Coinfusion of Autologous-Blood Stem Cells and Culture-Expanded Marrow Mesenchymal Stem Cells in Advanced Breast Cancer Patients Receiving High-Dose Chemotherapy

    Omer N. Koç;Stanton L. Gerson;Brenda W. Cooper;Stephanie M. Dyhouse

  • Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells

    Manas K. Majumdar;Mark A. Thiede;Joseph D. Mosca;Mark Moorman

  • Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients

    Hillard M. Lazarus;Omer N. Koc;Steven M. Devine;Peter Curtin

  • Hematopoietic Engraftment and Survival in Adult Recipients of Umbilical-Cord Blood from Unrelated Donors

    Mary J. Laughlin;Juliet Barker;Barbara Bambach;Omer N. Koc

  • MGMT: its role in cancer aetiology and cancer therapeutics.

    Stanton L. Gerson

  • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use.

    Hillard M Lazarus;Stephen E Haynesworth;Stanton L Gerson;N. S. Rosenthal

  • Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia.

    Stanton L. Gerson;George H. Talbot;Shelley Hurwitz;Brian L. Strom

  • Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH).

    O. N. Koç;J. Day;M. Nieder;Stanton L Gerson

  • Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages.

    Manas K. Majumdar;Mark A. Thiede;Stephen E. Haynesworth;Scott P. Bruder

  • Hematologic Effects of Linezolid: Summary of Clinical Experience

    Stanton L. Gerson;Sheldon L. Kaplan;Jon B. Bruss;Vu Le

  • Clinical Relevance of MGMT in the Treatment of Cancer

    Stanton L. Gerson

  • Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules

    A W Tolcher;S L Gerson;L Denis;C Geyer

  • Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation

    Wen Mei Yu;Xia Liu;Jinhua Shen;Olga Jovanovic

  • Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues.

    Stanton L. Gerson;Joan E. Trey;Kathleen Miller;Nathan A. Berger

  • Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases

    Omer N. Koç;Charles Peters;Patrick Aubourg;Shrini Raghavan

  • Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

    Yongyou Zhang;Amar Desai;Sung Yeun Yang;Sung Yeun Yang;Ki Beom Bae;Ki Beom Bae

  • Targeted modulation of MGMT: clinical implications

    Lili Liu;Stanton L. Gerson

  • The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase.

    Luba L. Dumenco;Esther Allay;Kathleen Norton;Stanton L. Gerson

  • Transduced mesenchymal stem cells

    Stanton L. Gerson;Arnold I. Caplan;Stephen E. Haynesworth

  • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.

    Lili Liu;Sanford Markowitz;Stanton L. Gerson

Frequent Co-Authors

Hillard M. Lazarus
Hillard M. Lazarus Case Western Reserve University
Marcos de Lima
Marcos de Lima The Ohio State University
Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
James K V Willson
James K V Willson The University of Texas at Dallas
Nathan A. Berger
Nathan A. Berger Case Western Reserve University
Arnold I. Caplan
Arnold I. Caplan Case Western Reserve University
Charles L. Hoppel
Charles L. Hoppel Case Western Reserve University
George H. Talbot
George H. Talbot Sanofi (France)
Anthony E. Pegg
Anthony E. Pegg Pennsylvania State University
James E. Dennis
James E. Dennis Baylor College of Medicine

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