D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 117 Citations 68,855 361 World Ranking 219 National Ranking 132

Research.com Recognitions

Awards & Achievements

2014 - Fellow, National Academy of Inventors

1992 - Member of the National Academy of Medicine (NAM)

1991 - Member of the National Academy of Sciences

1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of study are Mesenchymal stem cell, Stromal cell, Immunology, Cell biology and Stem cell. His study in Mesenchymal stem cell is interdisciplinary in nature, drawing from both Cell culture, Stem cell transplantation for articular cartilage repair, Inflammation, Proinflammatory cytokine and Bone marrow. His Stromal cell research integrates issues from CD34, Molecular biology, Downregulation and upregulation and Cellular differentiation.

His Molecular biology study also includes fields such as

  • Gene which connect with Osteogenesis imperfecta,
  • Cartilage that intertwine with fields like Genetically modified mouse and Spleen. Darwin J. Prockop has researched Immunology in several fields, including Progenitor cell, Multipotent Stem Cell and Cell. In most of his Stem cell studies, his work intersects topics such as Adult stem cell.

His most cited work include:

  • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement (10794 citations)
  • Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues (4256 citations)
  • Adult rat and human bone marrow stromal cells differentiate into neurons (2337 citations)

What are the main themes of his work throughout his whole career to date?

Darwin J. Prockop spends much of his time researching Molecular biology, Procollagen peptidase, Mesenchymal stem cell, Biochemistry and Gene. His Molecular biology research is multidisciplinary, relying on both Nucleic acid sequence, DNA, Complementary DNA, Messenger RNA and Polymerase chain reaction. His Mesenchymal stem cell study integrates concerns from other disciplines, such as Progenitor cell, Stromal cell and Immunology, Bone marrow.

His Stromal cell research is multidisciplinary, incorporating perspectives in In vitro and Cellular differentiation. Darwin J. Prockop focuses mostly in the field of Immunology, narrowing it down to matters related to Stem cell and, in some cases, Adult stem cell and Stem cell transplantation for articular cartilage repair. His research in Gene tackles topics such as Osteogenesis imperfecta which are related to areas like Internal medicine and Endocrinology.

He most often published in these fields:

  • Molecular biology (25.12%)
  • Procollagen peptidase (22.92%)
  • Mesenchymal stem cell (24.18%)

What were the highlights of his more recent work (between 2008-2020)?

  • Mesenchymal stem cell (24.18%)
  • Immunology (17.58%)
  • Stromal cell (17.74%)

In recent papers he was focusing on the following fields of study:

Darwin J. Prockop mainly focuses on Mesenchymal stem cell, Immunology, Stromal cell, Cell biology and Inflammation. His work deals with themes such as Progenitor cell, Stem cell, Cancer research and Bone marrow, which intersect with Mesenchymal stem cell. His Progenitor cell research incorporates themes from Clinical uses of mesenchymal stem cells, Notch signaling pathway, Cellular differentiation and Stem cell transplantation for articular cartilage repair.

The concepts of his Immunology study are interwoven with issues in Cell and In vitro. His Stromal cell research incorporates elements of Cell culture, Multipotent Stem Cell, Downregulation and upregulation, Molecular biology and In vivo. Darwin J. Prockop combines subjects such as Apoptosis, Cell adhesion, Flow cytometry and Anatomy with his study of Cell biology.

Between 2008 and 2020, his most popular works were:

  • Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 (1263 citations)
  • Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 (1263 citations)
  • Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties (576 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in Mesenchymal stem cell, Immunology, Stromal cell, Inflammation and Cancer research. His Mesenchymal stem cell research is included under the broader classification of Cell biology. Darwin J. Prockop works mostly in the field of Immunology, limiting it down to topics relating to Transplantation and, in certain cases, Spinal cord, Chronic inflammatory response, Cord and Spinal cord injury, as a part of the same area of interest.

The study incorporates disciplines such as Cell culture, Gene expression, Type II collagen, Multipotent Stem Cell and Downregulation and upregulation in addition to Stromal cell. His studies deal with areas such as Cancer and Lung injury, Lung as well as Cancer research. The Stem cell study combines topics in areas such as Stem cell transplantation for articular cartilage repair and Adult stem cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

M. Dominici;K. Le Blanc;I. Mueller;I. Slaper-Cortenbach.
Cytotherapy (2006)

15656 Citations

Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues

Darwin J. Prockop.
Science (1997)

6051 Citations

Adult rat and human bone marrow stromal cells differentiate into neurons

Dale Woodbury;Emily J. Schwarz;Darwin J. Prockop;Ira B. Black.
Journal of Neuroscience Research (2000)

4179 Citations

Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains

Gene C. Kopen;Darwin J. Prockop;Donald G. Phinney.
Proceedings of the National Academy of Sciences of the United States of America (1999)

2731 Citations

Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta

Edwin M. Horwitz;Darwin J. Prockop;Lorraine A. Fitzpatrick;Winston W. K. Koo.
Nature Medicine (1999)

2388 Citations

Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views.

Donald G. Phinney;Darwin J. Prockop.
Stem Cells (2007)

2218 Citations

COLLAGENS: Molecular Biology, Diseases, and Potentials for Therapy

Darwin J. Prockop;Kari I. Kivirikko.
Annual Review of Biochemistry (1995)

1867 Citations

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

Ryang Hwa Lee;Andrey A. Pulin;Min Jeong Seo;Daniel J. Kota;Daniel J. Kota.
Cell Stem Cell (2009)

1738 Citations

The biosynthesis of collagen and its disorders (first of two parts).

Darwin J. Prockop;Kari I. Kivirikko;Leena Tuderman;Norberto A. Guzman.
The New England Journal of Medicine (1979)

1620 Citations

Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats—similarities to astrocyte grafts

Azizi Sa;Stokes D;Augelli Bj;DiGirolamo C.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1474 Citations

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