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Genetics

D-Index
81
Citations
21747
World Ranking
1534
National Ranking
1

Medicine

D-Index
82
Citations
22511
World Ranking
16224
National Ranking
37

Overview

Gerard Tromp is a researcher affiliated with Stellenbosch University in South Africa, with a primary focus on medical and molecular biological sciences. Their work spans multiple disciplines with a strong emphasis on infectious diseases, epidemiology, genetics, and surgery.

The researcher has contributed extensively to tuberculosis research and epidemiology, with significant publications addressing Mycobacterium research and diagnosis. Their main topics of interest also include genetic associations and epidemiology, diagnosis and treatment of tuberculosis, pneumonia and respiratory infections, esophageal cancer research and treatment, as well as neutrophil, myeloperoxidase, and oxidative mechanisms.

The following list summarizes the key topics Gerard Tromp has worked on:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Genetic Associations and Epidemiology
  • Diagnosis and treatment of tuberculosis
  • Pneumonia and Respiratory Infections
  • Esophageal Cancer Research and Treatment
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Gerard Tromp's scholarly output includes contributions to multiple publication venues. The most frequent platforms for their research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Scientific Reports
  • Frontiers in Immunology
  • UNC Libraries

In terms of collaborations, the researcher has worked closely with several co-authors, reflecting a strong network in their field. Frequent coauthors include:

  • Gerhard Walzl
  • Gian van der Spuy
  • Stephanus T. Malherbe
  • Helena Kuivaniemi
  • Novel N. Chegou

Several notable publications illustrate Gerard Tromp's research contributions, including:

  • "RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response" (2020, Scientific Reports)
  • "Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results" (2021, Clinical Infectious Diseases)
  • "T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection" (2023, Nature Medicine)
  • "Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa" (2021, PLoS ONE)
  • "Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response" (2020, EJNMMI Research)

The researcher's work integrates multiple fields of study, mainly Medicine and Biochemistry, Genetics and Molecular Biology, substantiating their broad engagement with both clinical and molecular aspects of disease investigation.

Best Publications

  • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

    Anna Helgadottir;Gudmar Thorleifsson;Kristinn P Magnusson;Solveig Grétarsdottir

  • The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

    Omri Gottesman;Helena Kuivaniemi;Gerard Tromp;W. Andrew Faucett

  • Mutations in collagen genes: causes of rare and some common diseases in humans.

    Helena Kuivaniemi;Gerard Tromp;Darwin J. Prockop

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

    Catherine A. Brownstein;Alan H. Beggs;Nils Homer;Barry Merriman

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition.

    Tsuyoshi Tanabe;Tsuyoshi Tanabe;Mathias Chamaillard;Yasunori Ogura;Li Zhu

  • PheKB: A catalog and workflow for creating electronic phenotype algorithms for transportability

    Jacqueline Kirby;Peter Speltz;Luke V. Rasmussen;Melissa A. Basford

  • The X chromosome and sex-specific effects in infectious disease susceptibility

    Haiko Schurz;Haiko Schurz;Muneeb Salie;Gerard Tromp;Gerard Tromp;Eileen G. Hoal

  • Understanding the pathogenesis of abdominal aortic aneurysms

    Helena Kuivaniemi;Evan J Ryer;James R Elmore;Gerard Tromp

  • The phenotypic legacy of admixture between modern humans and Neandertals

    Corinne N. Simonti;Benjamin Vernot;Lisa Bastarache;Erwin Bottinger

  • Mutations in fibrillar collagens (types I, II, III, and XI), fibril‐associated collagen (type IX), and network‐forming collagen (type X) cause a spectrum of diseases of bone, cartilage, and blood vessels

    Helena Kuivaniemi;Gerard Tromp;Darwin J. Prockop

  • Familial intracranial aneurysms.

    Antti Ronkainen;Juha Hernesniemi;Matti Puranen;Lea Niemitukia

  • Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis

    Yeon Mee Kim;Roberto Romero;Tinnakorn Chaiworapongsa;Gi Jin Kim

  • Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.

    Stephanus T Malherbe;Shubhada Shenai;Katharina Ronacher;Katharina Ronacher;Andre G Loxton;Andre G Loxton

  • Bacterial vaginosis, the inflammatory response and the risk of preterm birth: a role for genetic epidemiology in the prevention of preterm birth.

    Roberto Romero;Tinnakorn Chaiworapongsa;Helena Kuivaniemi;Gerard Tromp

  • Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis

    Sara Suliman;Ethan G. Thompson;Jayne Sutherland;January Weiner rd

  • Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases.

    Helena Kuivaniemi;Gerard Tromp

  • Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays

    Madhumita Chatterjee;Saroj Mohapatra;Alexei Ionan;Gagandeep Bawa

  • Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature

    Ramsi Haddad;Gerard Tromp;Helena Kuivaniemi;Tinnakorn Chaiworapongsa

Frequent Co-Authors

Helena Kuivaniemi
Helena Kuivaniemi Stellenbosch University
Roberto Romero
Roberto Romero National Institutes of Health
Darwin J. Prockop
Darwin J. Prockop Texas A&M University
Marylyn D. Ritchie
Marylyn D. Ritchie University of Pennsylvania
David J. Carey
David J. Carey Geisinger Health System
Joshua C. Denny
Joshua C. Denny National Institutes of Health
Gail P. Jarvik
Gail P. Jarvik University of Washington
Erwin P. Bottinger
Erwin P. Bottinger Hasso Plattner Institute
Catherine A. McCarty
Catherine A. McCarty University of Minnesota
Tinnakorn Chaiworapongsa
Tinnakorn Chaiworapongsa Wayne State University

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