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Biology and Biochemistry

D-Index
86
Citations
26369
World Ranking
2967
National Ranking
1518

Overview

David J. Carey is affiliated with the Geisinger Health System in the United States and has a research focus primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Genetics, Molecular Biology, Surgery, Epidemiology, and Pulmonary and Respiratory Medicine.

Their research covers a range of main topics such as Genetic Associations and Epidemiology, Genomics and Rare Diseases, BRCA gene mutations in cancer, Pancreatic function and diabetes, Liver Disease Diagnosis and Treatment, Renal and related cancers, and Epigenetics and DNA Methylation.

Frequent co-authors collaborating with Carey include Jeremy S. Haley, Uyenlinh L. Mirshahi, Jung Kim, Diane T. Smelser, and Alan R. Shuldiner.

Their contributions have been published in several venues, with multiple papers appearing in bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Genetics in Medicine Open, Nature Communications, and The American Journal of Human Genetics.

Notable recent papers authored or co-authored by Carey include:

  • Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure (2020, Nature Communications)
  • Exome sequencing and characterization of 49,960 individuals in the UK Biobank (2020, Nature)
  • Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity (2021, Science)
  • Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population (2023, JAMA)
  • Germline Mutations in CIDEB and Protection against Liver Disease (2022, New England Journal of Medicine)

Best Publications

  • Syndecans: multifunctional cell-surface co-receptors.

    David J. Carey

  • Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

    Frederick E Dewey;Viktoria Gusarova;Richard L Dunbar;Colm T O'Dushlaine

  • Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

    S Shah;A Henry;C Roselli;H Lin

  • A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

    Noura S. Abul-Husn;Xiping Cheng;Alexander H. Li;Yurong Xin

  • Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

    Jonas B. Nielsen;Rosa B. Thorolfsdottir;Rosa B. Thorolfsdottir;Lars G. Fritsche;Wei Zhou

  • Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

    Derek Klarin;Derek Klarin;Scott M Damrauer;Scott M Damrauer;Kelly Cho;Yan V Sun

  • The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

    Omri Gottesman;Helena Kuivaniemi;Gerard Tromp;W. Andrew Faucett

  • Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

    Frederick E. Dewey;Viktoria Gusarova;Colm O'Dushlaine;Omri Gottesman

  • Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

    Frederick E. Dewey;Michael F. Murray;John D. Overton;Lukas Habegger

  • In vivo and in vitro observations on laminin production by Schwann cells

    C J Cornbrooks;D J Carey;J A McDonald;R Timpl

  • Genetic identification of familial hypercholesterolemia within a single U.S. health care system

    Noura S. Abul-Husn;Kandamurugu Manickam;Laney K. Jones;Eric A. Wright

  • Exome sequencing and characterization of 49,960 individuals in the UK Biobank.

    Cristopher V Van Hout;Ioanna Tachmazidou;Ioanna Tachmazidou;Joshua D Backman;Joshua D Hoffman

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • The Geisinger MyCode community health initiative: an electronic health record-linked biobank for precision medicine research.

    David J. Carey;Samantha N. Fetterolf;F. Daniel Davis;William A. Faucett

  • Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3).

    Erkki Raulo;Michael Chernousov;David Carey;Riitta Nolo

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Louise V. Wain;Nick Shrine;María Soler Artigas;A. Mesut Erzurumluoglu

  • Molecular cloning and characterization of N-syndecan, a novel transmembrane heparan sulfate proteoglycan

    DJ Carey;DM Evans;RC Stahl;VK Asundi

  • Control of Growth and Differentiation of Vascular Cells by Extracellular Matrix Proteins

    David J. Carey

  • Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

    Solveig Gretarsdottir;Annette F. Baas;Gudmar Thorleifsson;Hilma Holm

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Nick Shrine;Maria Soler Artigas;A. Mesut Erzurumluoglu

Frequent Co-Authors

Gerard Tromp
Gerard Tromp Stellenbosch University
Marylyn D. Ritchie
Marylyn D. Ritchie University of Pennsylvania
Helena Kuivaniemi
Helena Kuivaniemi Stellenbosch University
H. Lester Kirchner
H. Lester Kirchner Geisinger Health System
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Colm O'Dushlaine
Colm O'Dushlaine insitro Inc.
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Unnur Thorsteinsdottir
Unnur Thorsteinsdottir deCODE Genetics (Iceland)
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Jeffrey G. Reid
Jeffrey G. Reid Regeneron (United States)

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