His main research concerns Immunology, Immune system, Cholera toxin, Adjuvant and Antigen. In the subject of general Immunology, his work in Antibody, Germinal center, Inflammation and Immunoglobulin A is often linked to Lamina propria, thereby combining diverse domains of study. His work is dedicated to discovering how Immune system, Nasal administration are connected with Immunogen and Viral matrix protein and other disciplines.
His Cholera toxin research is multidisciplinary, relying on both T cell, Antigen presentation, Molecular biology and Intestinal permeability. His Adjuvant research is multidisciplinary, incorporating elements of Acquired immune system, Mechanism of action, Influenza vaccine, Epitope and Keyhole limpet hemocyanin. Many of his studies on Antigen involve topics that are commonly interrelated, such as Microbiology.
His primary areas of study are Immunology, Immune system, Adjuvant, Cholera toxin and Antigen. His Immunology study is mostly concerned with Immunity, Germinal center, Antibody, Immunization and T cell. His research in Immune system focuses on subjects like Inflammation, which are connected to Arthritis and Gastritis.
He focuses mostly in the field of Adjuvant, narrowing it down to matters related to Virology and, in some cases, Chlamydia. Nils Lycke combines subjects such as CD86, Adjuvanticity, Fusion protein, Keyhole limpet hemocyanin and CD80 with his study of Cholera toxin. His research in Antigen intersects with topics in Molecular biology, Antigen presentation and Microbiology.
His primary areas of investigation include Immunology, Immune system, Antigen, Adjuvant and Antibody. His Immunology research incorporates elements of Cholera toxin and Virology. His study in the field of Priming and T cell is also linked to topics like CXCL13 and CD11c.
His Antigen research integrates issues from Adoptive cell transfer, FOXP3, Microbiology and Nasal administration. His work deals with themes such as Toxin, Liposome, Immunogenicity and Vaccination, which intersect with Adjuvant. His Antibody research includes elements of Virus, Molecular biology and Connective tissue.
Nils Lycke focuses on Immunology, Adjuvant, Antibody, Immunity and Cholera toxin. His study brings together the fields of Virology and Immunology. In his research on the topic of Adjuvant, Chlamydia is strongly related with Vaccination.
His work in Immunity covers topics such as Antigen which are related to areas like Nasal administration, Liposome and Adoptive cell transfer. His Cholera toxin research is multidisciplinary, incorporating perspectives in Mechanism of action, Interleukin 12, Integrin alpha M and Enterotoxin. His Immune system study combines topics in areas such as Epitope and Cytotoxic T cell.
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Recent progress in mucosal vaccine development: potential and limitations
Nils Lycke.
Nature Reviews Immunology (2012)
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens
N Lycke;J Holmgren.
Immunology (1986)
Cholera toxin and cholera B subunit as oral—mucosal adjuvant and antigen vector systems
Jan Holmgren;Nils Lycke;Cecil Czerkinsky.
Vaccine (1993)
Murine CD4 T-cell response to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load.
Marjan Mohammadi;John Nedrud;Ray Redline;Nils Lycke.
Gastroenterology (1997)
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity.
Nils Lycke;Takao Tsuji;Jan Holmgren.
European Journal of Immunology (1992)
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues.
C Czerkinsky;M W Russell;N Lycke;M Lindblad.
Infection and Immunity (1989)
Impaired mucosal immune responses in interleukin 4-targeted mice.
M Vajdy;M H Kosco-Vilbois;M Kopf;G Köhler.
Journal of Experimental Medicine (1995)
Mucosal Immunity: Implications for Vaccine Development
Jan Holmgren;Cecil Czerkinsky;Nils Lycke;Ann-Mari Svennerholm.
Immunobiology (1992)
Isolation of mouse small intestinal intraepithelial lymphocytes, Peyer's patch, and lamina propria cells.
Leo Lefrançois;Nils Lycke.
Current protocols in immunology (2001)
Protection against Helicobacter pylori infection following immunization is IL-12-dependent and mediated by Th1 cells.
Ali A. Akhiani;Jacques Pappo;Zita Kabok;Karin Schön.
Journal of Immunology (2002)
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