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Immunology

D-Index
63
Citations
20129
World Ranking
2987
National Ranking
265

Research.com Recognitions

  • 2016 - Fellow of the Royal Society of Edinburgh

Overview

Allan McI. Mowat is affiliated with the University of Glasgow in the United Kingdom. The focus of their research lies primarily within the fields of immunology and microbiology, with substantial contributions to biochemistry, genetics, and molecular biology. Their work also spans several subfields including immunology, molecular biology, genetics, oncology, and biotechnology.

Their main research topics encompass immune cell function and interaction, immunotherapy and immune responses, T-cell and B-cell immunology, gut microbiota and health, immune cells in cancer, cancer cells and metastasis, as well as single-cell and spatial transcriptomics.

Significant recent publications include:

  • The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease, 2021, Scientific Reports
  • Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3 + CD8 + T regs, 2021, Science Immunology
  • IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage, 2022, Immunity
  • The small and large intestine contain related mesenchymal subsets that derive from embryonic Gli1+ precursors, 2023, Nature Communications
  • Immunological roles of intestinal mesenchymal cells, 2020, Immunology

Frequent co-authors in their publications include William W. Agace, Simon Milling, Calum C. Bain, Julien Vandamme, and Line Wulff.

The scientist has published multiple articles in high-profile venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Reviews Immunology, Mucosal Immunology, Science Immunology, and Scientific Reports. The highest number of publications have appeared in bioRxiv and Nature Reviews Immunology.

In recognition of their contributions, Allan McI. Mowat was named a Fellow of the Royal Society of Edinburgh in 2016.

Best Publications

  • Anatomical basis of tolerance and immunity to intestinal antigens

    Allan McI. Mowat

  • Regional specialization within the intestinal immune system

    Allan M. Mowat;William Winston Agace

  • Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

    Calum C Bain;Alberto Bravo-Blas;Charlotte L Scott;Elisa Gomez Perdiguero

  • Oral tolerance to food protein

    O Pabst;A M Mowat

  • The anatomical basis of intestinal immunity.

    Allan McI. Mowat;Joanne L. Viney

  • Macrophages in intestinal homeostasis and inflammation

    Calum C Bain;Allan McI Mowat

  • Immune responses to dietary antigens: oral tolerance

    Stephan Strobel;Allan McI Mowat

  • Unravelling mononuclear phagocyte heterogeneity

    Frédéric Geissmann;Siamon Gordon;David A Hume;Allan M Mowat

  • Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

    Calum C. Bain;Catherine A. Hawley;Hannah Garner;Charlotte L. Scott

  • CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

    Samira Tamoutounour;Samira Tamoutounour;Samira Tamoutounour;Sandrine Henri;Sandrine Henri;Sandrine Henri;Hugues Lelouard;Hugues Lelouard;Hugues Lelouard;Béatrice de Bovis;Béatrice de Bovis;Béatrice de Bovis

  • Intestinal CD103+ dendritic cells: master regulators of tolerance?

    Charlotte L. Scott;Aude M. Aumeunier;Allan McI. Mowat

  • Expanding Dendritic Cells In Vivo Enhances the Induction of Oral Tolerance

    Joanne L. Viney;Allan M. Mowat;Jamie M. O’Malley;Eilidh Williamson

  • Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

    V. Cerovic;S. A. Houston;Charlotte Scott;A. Aumeunier

  • Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

    Nicholas A. Scott;Nicholas A. Scott;Anna Andrusaite;Peter Andersen;Melissa Lawson

  • Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles.

    K J Maloy;A M Donachie;D T O'Hagan;A M Mowat

  • Immunomodulatory dendritic cells in intestinal lamina propria

    Fernando G. Chirdo;Fernando G. Chirdo;Owain R. Millington;Helen Beacock-Sharp;Allan McI. Mowat

  • Mucosal Macrophages in Intestinal Homeostasis and Inflammation

    Allan McI Mowat;Calum C. Bain

  • Intestinal macrophages and dendritic cells: what's the difference?

    Vuk Cerovic;Calum C. Bain;Allan McI. Mowat;Simon W. F. Milling

  • Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route.

    A M Mowat;A M Donachie;G Reid;O Jarrett

  • Antibodies to IFN-gamma prevent immunologically mediated intestinal damage in murine graft-versus-host reaction.

    A M Mowat

Frequent Co-Authors

Paul Garside
Paul Garside University of Glasgow
Kevin J. Maloy
Kevin J. Maloy University of Oxford
Bernard Malissen
Bernard Malissen Aix-Marseille University
William W. Agace
William W. Agace University of Copenhagen
Sandrine Henri
Sandrine Henri Centre d’Immunologie de Marseille-Luminy
Martin Guilliams
Martin Guilliams Ghent University
Nils Lycke
Nils Lycke University of Gothenburg
Frederic Geissmann
Frederic Geissmann Memorial Sloan Kettering Cancer Center
Margaret M. Harnett
Margaret M. Harnett University of Glasgow
Daniel A. Peterson
Daniel A. Peterson Rosalind Franklin University of Medicine and Science

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